Erythema and ecchymosis after newborn’s phototherapyA male infant is born and delivery is remarkable for yellow amniotic fluid and a jaundiced infant. Following delivery he is given intensive phototherapy and then develops erythema, which later becomes ecchymosis. What's the diagnosis?
Psoriasis and skin cancerCyclosporine and PUVA clearly increase the risk of squamous cell carcinomas, and there is evidence that TNF blockers and methotrexate may do so to a lesser degree. UVB phototherapy has not been shown to cause skin cancer. Acitretin offers protection against the development of basal cell and squamous cell carcinomas.
Phototherapy could be associated with neonatal cancerAlthough phototherapy is an established and valuable treatment for infants with neonatal hyperbilirubinemia, some investigations have raised concerns that the treatment is associated with cancer.
FDA approves ixekizumab for plaque psoriasisThe FDA approved Taltz (ixekizumab, Eli Lilly and Company) injection 80 mg/mL March 22 for treatment of moderate-to-severe plaque psoriasis in adult patients who are candidates for systemic therapy or phototherapy. Learn more
Managing progressive keratoconus with the triple procedureFindings from a study undertaken at Dr Lovisolo’s practice indicate that in carefully-selected patients, a triple procedure, comprising Keraring implantation followed by accelerated CXL and topo-guided ablation can provide significant functional improvement in cases of progressive keratoconus.
Combination therapy outpaces monotherapy in vitiligo trialA new study suggests the combination therapy of afamelanotide implant and narrowband ultraviolet B (NB-UVB) phototherapy is more effective than NB-UVB therapy alone in treating vitiligo.
Delayed clamping won’t harm mothers, benefits infantsThe common practice of clamping an umbilical cord within a minute of birth to reduce the possibility of maternal hemorrhaging may need to be revised, according to a new paper published in The Cochrane Database of Systematic Reviews. The study authors searched the Cochrane Pregnancy and Childbirth Group’s Trials Register to find 15 trials involving a total of 3911 mother and infant pairs. The risk of bias in the trials was considered by the paper’s authors to be moderate in nature.