How to use tear osmolarity to help treat dry eye disease For the patient, perhaps the most significant symptom of DED is fluctuating or reduced vision. The utility of normal tear osmolarity results Patient symptoms are not an effective method to diagnose dry eye, as they often overlap with other pathologies. Tear osmolarity results provide clues for alternative diagnoses. Getting beyond the surface in ocular surface disease September 01, 2016 By Laura M. Periman MD Ocular surface disease (OSD) is a prevalent, chronic, and progressive condition with an often multifactorial etiology. A comprehensive approach to detection, treatment, and monitoring is required. How punctal plugs may influence tear osmolarity and aid in dry eye therapies March 15, 2016 By Lynda Charters Tear osmolarity decreases with punctal plug insertion and serves as a leading indicator of therapeutic efficacy in dry eye disease. Natural oral omega-3 supplement improves dry eye parameters in 3 months The natural triglyceride form of omega-3 is an excellent treatment option for dry eye disease. Addressing punctal occlusion, tear osmolarity correlation Patients with elevated tear osmolarity who underwent punctal occlusion showed rapid improvement in tear osmolarity and other features of dry eye disease. Studies confirm tear osmolarity is central to OSD Doctors, researchers, and clinical studies have evaluated how tear osmolarity is impacted by a variety of conditions in vivo, in vitro, and in animal models. The conclusions show that tear osmolarity is an integral factor in the complex condition of ocular surface disease.