Pseudoexfoliation syndrome

Cataract surgery for patients with PXFMom has pseudoexfoliation syndrome (PXF) clinically visible in both eyes. She experiences pops of elevated intraocular pressure (IOP) in one eye and uses glaucoma medications.
Roles of Klotho and Endothelin-1 in pseudoexfoliationSerum and aqueous levels of Klotho levels are reduced in pseudoexfoliation syndrome (PXF) and pseudoexfoliative glaucoma (PEG) while Endothelin-1 (ET-1) is increased, researchers say.
Cataract surgery cuts glaucoma risk in eyes with pseudoexfoliationCataract surgery appears to reduce the risk of glaucoma in eyes with pseudoexfoliation (PEX) syndrome, researchers said.
Pseudoexfoliation may play greater role in late IOL subluxation/dislocationHistopathologic analysis of 53 consecutive IOL-capsular bag specimens explanted after late in-the-bag IOL subluxation/dislocation identified pseudoexfoliation in 33(62%) of cases—less than half of which had a clinical diagnosis of pseudoexfoliation.
CTR does not avert spontaneous IOL dislocation
CTR does not avert spontaneous IOL dislocationIn what is believed to be the largest reported series of spontaneous in-the-bag IOL dislocation, investigators analyze presenting characteristics and outcomes for 21 eyes with a capsular tension ring (CTR) and 84 eyes without one.
Postop considerations for pseudoexfoliation after cataract surgery
Postop considerations for pseudoexfoliation after cataract surgeryPostoperative patients with PXF pose both short- and long-term concerns due to the underlying pathological changes that occur from the fibrillar deposition with some complications arising years after the surgery.
Pseudoexfoliation syndrome not yet ready for genetic testingAlthough the LOXL1 gene may increase the risk for pseudoexfoliation syndrome, currently available genetic testing does not effectively predict who will develop disease.
Preoperative considerations in patients with cataracts and pseudoexfoliation syndromePreoperative evaluation of patients with pseudoexfoliation (PXF) syndrome is essential in preparing for and potentially preventing complications during phacoemulsification. Patients with PXF have been documented to have an accelerated rate of cataracts, both nuclear and subcapsular.
PEX associated with CVD, CVA in meta-analysisPseudoexfoliation syndrome (PEX) appears to be significantly associated with both cardiovascular (CVD) and cerebrovascular disease (CVA), according to a new meta-analysis, said Helen Chung, MD.