Riboflavin

Collagen corneal cross-linking for keratoconusThe recently approved procedure will help many with this progressive disease
Clinical implications of corneal cross-linkingNow that we have CXL , it is imperative for clinicians to incorporate new technologies that can help us achieve disease detection at the earliest clinical stage prior to onset of visual symptoms.
Impact of nutritional deficiencies on migrainesNutritional deficiencies may play a role in the development and/or perpetuation of migraines in children, according to a new study, but further research is needed to determine if supplementation would help.
Photoactivation holds promise for keratitis treatment
Photoactivation holds promise for keratitis treatmentThe same photoactivation process used in collagen cross-linking for keratoconus can kill bacteria without the need for the oxygen responsible for the biomechanical effects, potentially pointing toward better treatments for keratitis, according to Olivier Richoz, MD, PhD.
A closer look at riboflavin application for corneal collagen crosslinkingCorneal collagen crosslinking with riboflavin works well but requires further exploration to identify the best approach for various types of patients.
Riboflavin delivery methods advance as techniques evolveTechniques for performing corneal collagen crosslink (CXL) are being evaluated and adapted, and at the same time, new applications are being developed.
Examining advances in EPI-ON CXL for keratoconusEpithelial-on crosslinking seems to be effective and safe for treating keratoconus as the result of the combination of a new formulation of riboflavin with a higher level of ultraviolet light. This technique resulted in improvements in corneal shape, uncorrected visual acuity, and best spectacle-corrected visual acuity.
Study: Ionotophoresis efficient, effective for riboflavin deliveryResults from preclinical studies and early clinical experience show that iontophoresis is an efficient and effective method for delivering riboflavin into the cornea, while CXL performed after the procedure is associated with good results in early follow-up.
Corneal collagen crosslinking indications expandingIndications for riboflavin ultraviolet crosslinking have been expanding. As such, the technology may be useful for more than just treating keratoconus—by filling a gap in which other surface therapies sometimes cannot be effective.
Seeking alternatives to CXL protocol for stromal saturationChemical enhancements to riboflavin solution aim to overcome need for epithelial debridement