Ozurdex

Study finds no VA benefit by adding corticosteroid implant to anti-VEGF injections
NICE recommends dexamethasone adalimumab for uveitisThe UK’s National Institute for Health and Care Excellence (NICE) has given preliminary approval to dexamethasone 0.7 mg intravitreal implant (Ozurdex, Allergan) and adalimumab (Humira, AbbVie) for sight-threatening non-infectious posterior uveitis.
New paradigm shift in selecting a steroid course prior to FAc implantAs retinal specialists, we are truly fortunate to live in a time where we have several treatment options for patients with diabetic macular edema (DME). A fluocinolone acetonide (FAc) intravitreal implant 0.19 mg (Iluvien, Alimera Sciences) is indicated for the treatment of DME in patients who have been previously treated with a course of corticosteroids and did not have a clinically significant rise in IOP.
Study tracks clinical use of dexamethasone implant for DMEA 6-month analysis from the REINFORCE study of the dexamethasone intravitreal implant Ozurdex found an average of one- to two-line vision gains and no new safety concerns.
Dexamethasone for DME shows stronger results compared with sham groupIn this article Dr Anat Lowenstein explains that the benefits of treatment with a dexamethasone intravitreal implant for DME were observed across a variety of demographic characteristics.
[BLOG] Pipeline advancement responsible for upturn in global pharma R&DThe world’s leading 30 pharmaceutical companies spent a combined $112 billion on research and development (R&D) in 2013, an increase of $723 million over the previous year. According to our new Global Pharmaceutical Benchmark Report, Roche was the R&D spending leader, outlaying nearly $10 billion in 2013. Meanwhile, Novartis and Johnson & Johnson (J&J) increased their R&D spend the most between 2012 and 2013, with each adding around $500 million to their respective clinics. Novartis’ R&D spending grew by 5.6% to $9.8 billion, and J&J spent $8.2 billion, which was up by 6.8% from 2012.
DME treatment advancements on horizonThere has been considerable progress in treatment for diabetic macular edema (DME) in the last several years, but a look at the investigational pipeline indicates further advances are likely on the horizon, said Peter A. Campochiaro, MD.
Allergan treatment for DME extended in EUThe European Commission has extended the marketing authorization for Allergan’s dexamethasone 700-mcg intravitreal implant in applicator (Ozurdex) to treat adult patients with visual impairment due to diabetic macular edema (DME).
Future of uveitis therapy takes shape with new treatmentsPotentially effective new drugs are in the pipeline for treating uveitis, in addition to several promising formulations in clinical trials.
Dexamethasone for DME delivers long-term visual benefitsA dexamethasone implant provides long-term visual improvements in patients with diabetic macular edema treated with two doses of the drug.