squamous cell carcinoma

Skin cancer advancesGenetic profiling is valuable in both diagnosis and prognosis of skin cancer. Hedgehog inhibitors and (superficial radiation therapy) SRT are strong contenders for treating nonmelanoma skin cancer. Advances in targeted therapies and biologics are part of the new wave of melanoma treatments.
Psoriasis and skin cancerCyclosporine and PUVA clearly increase the risk of squamous cell carcinomas, and there is evidence that TNF blockers and methotrexate may do so to a lesser degree. UVB phototherapy has not been shown to cause skin cancer. Acitretin offers protection against the development of basal cell and squamous cell carcinomas.
Improving accuracy in NMSC diagnosisThe trend toward smaller biopsies may compromise the accuracy of dermatopathologists' diagnoses.
GlobalMed Technologies acquires Omnilux MedicalGlobalMed has represented medical and aesthetic dermatology brands, including BMT, CoolTouch and Radiancy, since 1996. Omnilux noninvasively treats dermatologic conditions, including acne, fine lines and wrinkles and non-melanoma skin cancer.
Cutting edge techniques provide options for skin cancerNew technologies for managing skin cancer were a topic of discussion at a scientific session at the American Society for Dermatologic Surgery’s 2015 annual meeting in Chicago in October. Seaver L. Soon, M.D., division of dermatology and dermatologic surgery at Scripps Clinic, La Jolla, Calif., was one of the moderators for the scientific discussion titled, “The Cutting Edge: New Technologies for Managing Skin Cancer.” Learn more
High-risk skin cancer needs multidisciplinary management
High-risk skin cancer needs multidisciplinary managementImmunosuppressed patients have a greater risk for developing high-risk non-melanoma skin cancer, which can typically be more aggressive in this patient population. As such, a multidisciplinary approach is required when contemplating appropriate treatment and management of this patient population.
Compliance critical with at-home txDue to the complexities and follow-up requirements of nonsurgical treatments for skin cancer, patient selection is critical. Expert offers tips for using various noninvasive treatment options for BCC, SCC, and melanoma.
Evidence-based guidelines for managing challenging NMSCOngoing research is trying to identify strategies for overcoming resistance of advanced basal cell carcinoma to targeted therapy with a Hedgehog inhibitor. High level evidence to support adjuvant radiotherapy for high-risk non-melanoma skin cancers is lacking, but certain patients warrant evaluation by a multidisciplinary tumor board and treatment with adjuvant radiotherapy based on their risk for recurrence.
Hh inhibitors a less invasive tx for BCCAdvances in research have led to the emergence of medical therapies for BCCs; more research is needed to develop systemic therapies to treat SCCs.
Two TKIs go head-to-head in squamous cell carcinoma of the lung studyIn patients with advanced squamous cell carcinoma (SCC), afatinib significantly improved overall survival (OS) compared to erlotinib, according to data presented at the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago.