sickle cell disease

How to diagnose angioid streaks
How to diagnose angioid streaksAngioid streaks are a rare but potentially visually debilitating condition that present a unique challenge to the average eyecare provider. Learning to recognize its clinical presentation is just a start in an often difficult diagnosis to differentiate it from other similar retinal presentations. Ultimately understanding its association with a variety of systemic diseases is essential in successfully identifying and mitigating its link to vision loss.
FDA Approves First Drug for Sickle Cell in 20 YearsEndari is only the second FDA-approved sickle cell disease drug.
Crizanlizumab helps prevent pain crises in sickle cell diseaseIn patients with sickle cell disease, therapy with crizanlizumab, an antibody against the adhesion molecule P-selectin, resulted in a significantly lower rate of sickle cell-related pain crises than placebo, a trial in 198 patients aged from 16 to 65 years showed.
Gene therapy could be ‘ultimate solution’ for sickle cell diseaseInvestigational gene therapies might reduce the suffering and death caused by this genetic disease.
Readers note inconsistencies in Puzzler caseReaders discuss some inconsistencies that they discovered in the February Puzzler, and the authors respond.
FDA drug approvals-April 2015FDA actions in brief, priority review, breakthrough therapy designation, fast-track designations, orphan drug designations, first-time generic approvals
Legally Speaking: Tubal ligation failure results in wrongful pregnancy claim
Legally Speaking: Tubal ligation failure results in wrongful pregnancy claimSix months after a tubal ligation, a woman became pregnant. She gave birth by cesarean to a child who was diagnosed with sickle cell disease.
Choking and cyanosis in an infant with sickle cell diseaseA 2-month-old African American girl who presented to the emergency department with 2 episodes of apnea or gasping respirations associated with feeds is admitted by your general inpatient pediatric service.
Sickle cell disease in pregnancy
Sickle cell disease in pregnancyPregnancy is risky for women with sickle cell disease. This overview examines concerns for the mother and fetus to help you manage the risks.
New treatment guidelines for sickle cell diseaseExpand treatment of sickle cell disease with 2 “underused” preventive therapies to reduce painful flare-ups, an expert panel convened by the National Heart, Lung, and Blood Institute urges in new management guidelines.