in vitro fertilization

Elective single-embryo transfer: No longer elective
Elective single-embryo transfer: No longer electiveThe large body of evidence citing the effectiveness of IVF and recent advances promoting the safety of ART, including the widespread adoption of SET, have established IVF as a reasonable first-line alternative for many infertile couples rather than the treatment of last resort it was once regarded.
Meta-analysis on oocyte donation and perinatal outcomesA systematic review and meta-analysis suggests that in pregnancies conceived via assisted reproduction, risk of adverse perinatal outcomes may be higher with donated than with autologous oocytes. Plus: Do post-cesarean antibiotics reduce infections in obese women? Also: Researchers believe they have identified the genes associated with preterm delivery.
Fertility services can be attractive benefitTwo fertility experts detail the pros and cons of a fertility benefit plan.
UK approves three-parent fertility treatments and more researchA form of assisted reproductive technology that could make it possible for women with mutations in mitochondrial DNA to give birth to children free of mitochondrial disease has been approved by UK’s House of Commons. A Food and Drug Administration (FDA) committee is considering granting similar approval for use of the technique—known as oocyte modification or three-parent gene therapy—in the United States.
Use of ICSI on rise, but are outcomes better?
Use of ICSI on rise, but are outcomes better?Results of a retrospective cohort study show that use of intracytoplasmic sperm injection is on the rise but cast doubt on whether the technology is improving reproductive outcomes. Brian Levine, MD, MS provides commentary.
ICSI use doubles despite lack of improved outcomesThe analysis looked at intracytoplasmic sperm injection use and reproductive outcomes between 1996 and 2012. fertilization. Learn why
Does cryopreservation of embryos increase risk of placenta accreta?A small study by investigators from Harvard University suggests that cryopreserved embryo transfer (CET) is a strong independent risk factor for placenta accreta in women undergoing in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI).
Is thyroid dysfunction more common in children conceived via IVF?First-trimester exposure to maternal estradiol may increase risk of thyroid dysfunction in offspring conceived via in vitro fertilization (IVF), according to a study in Fertility & Sterility.
Is vitamin D deficiency linked with infertility?A prospective Italian study published in The Journal of Clinical Endocrinology & Metabolism suggests that low levels of vitamin D [25(OH)D] may contribute to infertility. The finding, which the authors acknowledge does not confirm causality, could point to possible therapeutic benefits of the vitamin in women undergoing in vitro fertilization (IVF).
Poor response to IVF linked to higher miscarriage riskAccording to a recent study in Human Reproduction, women who produce a low number of oocytes during in vitro fertilization (IVF) seem to have an increased risk of miscarriage.