targeted therapy

Skin cancer advancesGenetic profiling is valuable in both diagnosis and prognosis of skin cancer. Hedgehog inhibitors and (superficial radiation therapy) SRT are strong contenders for treating nonmelanoma skin cancer. Advances in targeted therapies and biologics are part of the new wave of melanoma treatments.
Personalized strategies critical for childhood cancerNext-generation gene sequencing and other advanced technologies for personalized medicine may soon identify biomarkers that will improve treatment response and long-term toxicity risks for childhood cancer patients.
Quality of life impact of anticancer drugsThe development of novel targeted anticancer therapies are proving to have a significant impact in the treatment and management of cancer patients; however, these agents also are associated with a distinct set of cutaneous side effects. Learn more.
Targeted therapy and adoptive T-cell therapy offer alternatives to immunotherapyOther strategies such as adoptive T-cell therapy are initiated when immune therapies fail to stop disease progression in advanced melanoma.
Targeting your melanoma therapyMelanoma is a genetically heterogeneous condition that will likely result in more diversified clinical management in the future.
Cutaneous T-cell lymphoma: Poised for a new treatment paradigmResearchers are aiming to better understand the molecular signaling pathways and the immune microenvironment of cutaneous T-cell lymphoma. The use of targeted or mechanism-based therapies may lead to better-understood combinations, higher response rates and better survival.
Vismodegib effective for treating challenging basal cell carcinomasVismodegib (Erivedge, Genentech) is demonstrating effectiveness for the treatment of metastatic and locally advanced basal cell carcinoma (BCC), offering hope for patients with this notoriously challenging disease.