pruritus

Pruritic vesicles erupt on a boy’s legsA healthy 12-year-old boy with eczema shows up at the office with an incredibly itchy rash on his legs that has exploded over the last 48 hours. He has a history of dry skin to which his mother regularly applies various moisturizers, including calendula oil.
Open access journal Itch launchesItch publishes original scientific papers that contribute to the understanding of the basic mechanisms and clinical aspects of pruritus. Unlike a printed journal, Itch’s online format allows for papers to be published after they’ve been reviewed.
Study enrollment for prurigo nodular completeA phase 2/3 multi-center, randomized, double-blind, placebo-controlled, parallel, three-arm study looking at Nalbuphine ER for prurigo nodularis will evaluate safety and efficacy in 63 patients.
Oatmeal soothes, relieves, and inhibits viruses
Oatmeal soothes, relieves, and inhibits virusesGood for more than a morning meal, oatmeal soothes angry skin, relieves itching, and even has an antimicrobial effect.
Hope for butterfly children
Hope for butterfly childrenEpidermolysis bullosa (EB) is often described as ‘the worst disease you’ve never heard of,’ and the young sufferer of this condition are referred to as ‘butterfly children’ because their skin is said to be fragile as the wings of butterflies. A potential new topical treatment option, in phase 3 trials, could help to change the EB treatment landscape.
Four drug categories can help to better manage chronic itch
Four drug categories can help to better manage chronic itchSuccessful treatment of chronic pruritus requires recognizing that its origins might not be as clear-cut as formerly thought, an expert says.
Combination therapies useful for severe scabies casesDifferent agents have become available for scabies treatment, but topical permethrin cream 5 percent is still the go-to therapy, according to an expert. In combination with oral ivermectin, even the most challenging cases of scabies can be addressed effectively.
Alternative therapies may be necessary for chronic itchWhen presented with a patient suffering from itching, dermatologists should consider treatments other than topical and oral medications, according to an expert who spoke at the 72nd Annual Meeting of the American Academy of Dermatology.
Finding cause of chronic pruritus helps to narrow down treatment strategiesAn accurate assessment of the potential cause of chronic pruritus, coupled by a careful selection of current standard treatments as well as new and emerging therapies, can be instrumental in helping to quell the symptoms of this sometimes severely debilitating condition.
AAD work groups aim to facilitate research within the specialtyThe American Academy of Dermatology (AAD) Council on Science and Research’s Research Agenda work group has identified three keys areas — pruritus, cutaneous oncology and performance measurement and outcomes — to target in the future for continuing research in the dermatology specialty.