melanoma

New target could predict melanomaNew information could eventually help identify a high-risk population before they get cancer — even prevent skin cancer’s onset.
Dermoscopy can enhance your diagnostic ability and accuracyThe role of dermoscopy has expanded beyond melanoma detection. Experts offer best practices and explain how to embrace and use this powerful tool to get more complete and accurate diagnoses.
Hyperpigmentation around a teen’s eyeAn adolescent girl is referred by her pediatrician to dermatology for evaluation of a birthmark on her face.
Scientists gain new insight into UV-exposure geneticsXeroderma pigmentosum is a rare disease that leads to early skin cancer. New insights may lead to better prevention and survival for patients, as well as point to ways that UV-resistant gene functions could be used for skin cancer prevention and treatment.
Gene tests predicts melanoma stagingA gene expression profile test rivals sentinel node biopsy in predicting distant metastasis in stage 1 and stage 2 melanoma, according to results from a new multicenter performance study.
Melanoma subtypes have different evolutionary pathsRecent research supports UV radiation as the major driving force in the initiation and progression of melanoma, and the same investigation demonstrated different paths of evolution for various melanoma subtypes.
Genetic tests guide cancer therapy, improve efficacyAt the ASCO 2016 Annual Meeting, an expert from the Moffitt Cancer Center will discuss use of genetics to guide targeted-therapies and immunotherapies.
Diagnostic techniques for desmoplastic melanomaDiagnosing challenging melanocytic lesions typically requires combining immunostains—such as S100 and P16—with the dermatopathologist's subjective judgment, says an expert. Adjunctive genetic tests and morphologic analysis can provide further clues, though neither method is infallible.
How to identify ocular cancerOptometrists in a practice unaffiliated with a tertiary care center will rarely see patients ocular cancer, a disease that is both sight threatening and life threatening. Because it’s impossible to predict who will walk through your door, it’s necessary to remain vigilant for signs of ocular melanoma, basal cell carcinoma, ocular lymphoma and leukemia, as well as cancers that have metastasized to the eye.
New compounds may block melanoma tumor growthEarly study results indicate the potential for a new class of inhibitory compounds to enhance the effect of anti-tumor drugs in melanoma treatment. What the future may hold.