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Testosterone Therapy and Cardiovascular Risk

Dr. Abraham Morgentaler, an Associate Clinical Professor of Urology at Harvard Medical School, explores and clarify in the February 2015 issue of Mayo Clinic Proceedings, the value of testosterone therapy in men, and in particular the issue of cardiovascular risk.

The Lowdown on Low T

FDA panel’s vote on TRT draws reaction from urologists
FDA panel’s vote on TRT draws reaction from urologistsAn FDA advisory committee has voted to restrict indications for testosterone replacement therapy and require additional clinical trials to test the safety of the drugs, decisions that have drawn mixed reactions from urologists.
Data fail to support concerns over T therapy, CV risk
Data fail to support concerns over T therapy, CV riskAll treatments entail some risk, including T therapy. At this point, there are no compelling data to support the notion that T therapy is associated with CV risks, and there is suggestive evidence it may even be helpful.
FDA approves another testosterone replacement gel
FDA approves another testosterone replacement gelThe FDA has approved a new testosterone gel formulation, marking the agency’s second approval of a testosterone replacement therapy in the course of a week.
Blood test poor diagnostic tool for hypogonadism
Blood test poor diagnostic tool for hypogonadismRelying on blood test results alone is insufficient for diagnosing hypogonadism, according to a recent study.
FDA approves injectable agent for hypogonadism
FDA approves injectable agent for hypogonadismThe FDA has approved testosterone undecanoate (AVEED) injection for treatment of men with hypogonadism.
Large-scale studies of testosterone therapy risks needed
Large-scale studies of testosterone therapy risks neededLarge-scale randomized, controlled trials are needed to determine the true risks and benefits of testosterone therapy in older men, the Endocrine Society said.
FDA investigating safety of testosterone products
FDA investigating safety of testosterone productsThe FDA said it is investigating the risk of stroke, heart attack, and death in men taking FDA-approved testosterone products.
Testosterone adversely affects fertility in some men
Testosterone adversely affects fertility in some menA recently published study found that a small percentage of men who seek infertility treatment are potentially hurting their ability to have children by taking testosterone supplements.
Testosterone often used without clear indicationAlthough testosterone use has increased significantly among older men in the past decade, many patients appear to have normal testosterone levels and do not meet the clinical guidelines for treatment, according to new research.
High T linked to poor response to flu vaccineResearchers say they have linked high testosterone levels in men to a poor immune response to an influenza vaccine.