inflammation

Substance P: Dry eye and allergy’s mixed signal or missing link?Inflammation may lead to heightened peripheral sensitization and stimulation through a developing concept in which neuroimmune cross-talk causes the confounding interplay of both signs and symptoms in dry eye and allergic disease.
Understanding the role of inflammation in dry eye
Understanding the role of inflammation in dry eyeOptometry Times Editorial Advisory Board members Leslie E. O’Dell. OD, FAAO, and Scott Hauswirth, OD, FAAO, discuss their recent lecture on inflammation and the role it plays in ocular surface diseases at the American Optometric Association’s Optometry’s Meeting in Washington, DC.
Limiting inflammation may decrease nerve damage, preserve cell functionEvidence supports the involvement of an important pathway in retinal ganglion cell dysfunction and death in traumatic optic neuropathy.
Asthma and kidney stones linked in childrenChildren with asthma are 4 times more likely to have kidney stones than those without asthma, and vice versa, according to a study published online in the medical journal PLoS One.
Factoring the metabolic X syndrome
Factoring the metabolic X syndromeAlthough there is debate surrounding the definition of metabolic X syndrome in pediatrics and there are few long-term studies of outcomes in children with metabolic syndrome, pediatric metabolic syndrome needs to be on the radar of all pediatricians interested in ensuring a healthy adult life for their patients.
Getting beyond the surface in ocular surface diseaseOcular surface disease (OSD) is a prevalent, chronic, and progressive condition with an often multifactorial etiology. A comprehensive approach to detection, treatment, and monitoring is required.
Diagnosing and treating Sjögren's syndrome
Diagnosing and treating Sjögren's syndromeSjögren’s syndrome is underdiagnosed and seriously impacts the ocular surface and quality of life and places the patient at risk for multisystem involvement. Optometry’s role in identification, diagnosis and collaborative long-term management is an important one. Earlier attention to symptoms leading to diagnosis and collaboration with other health professionals will ensure better quality of life for our patients.
Inflammasomes role in acne solidifiesExperts discuss association between inflammasomes and acne that may lead to treatments stopping acne before clinical signs emerge.
Exploring balance of controlling inflammation, IOP in uveitisClinicians need to weigh such factors as inflammation and IOP in determining when steroid therapy is beneficial in uveitic glaucoma.
Sustained-release formula may obviate need for post-cataract steroid therapyTwo phase III trials evaluated sustained-release dexamethasone for the treatment of inflammation and pain after cataract surgery.