Eye drops and ointments are prescribed by doctors to treat acute or long-term ocular conditions. Drops and ointments are administered directly in the site of action and are therefore very effective in treating the diagnosed condition.
In a recent wave of drug price increases that can only be explained by pharmaceutical manufacturers’ desire for profit maximization and which doctors and patients may call price gouging, the drug price war has been brought to the doorsteps of many eyecare providers. As optometrists are increasing their practice of medical optometry, patients are now calling their doctors about prior authorizations and unaffordable drug copays.
While no new drug shook up the world of glaucoma in 2015, a variety of promising agents made incremental advances toward the market with their true potential as yet unproven. Manufacturers have continued to refine approaches to existing drugs.
The lipid layer prevents evaporation of aqueous tears and prevents drying. Lipid deficiency due to meibomian gland dysfunction (MGD) is the most common cause of symptoms associated with dry eye disease.
This review presents a therapeutic nanowafer as an alternative to eye drops for dry eye disease, designed to enhance efficacy and improve patient compliance to treatment. In an experimental animal study, the novel dexamethasone nanowafer drug delivery system was comparable in efficacy to twice-daily dexamethasone eye drop treatment and has the potential to minimise risk of cataract formation and glaucoma.
Allergan recently issued a voluntary U.S. recall of its Refresh Lacri-Lube, Refresh P.M., FML (fluorometholone ophthalmic ointment) 0.1%, and Blephamide (sulfacetamide sodium and prednisolone acetate ophthalmic ointment) 10%/0.2% due to customer complaints of small black particles at the time of use.
Switching from brand to generic eye drops for surgical prophylaxis following cataract surgery caused no difference in endophthalmitis rates and resulted in substantial cost savings in a single-center comparison.