Edward J. Holland, MD

Non-invasive punctal plug delivery system offers a host of positive performance characteristics
Non-invasive punctal plug delivery system offers a host of positive performance characteristicsA silicone punctal plug-based delivery system for ophthalmic medications (Evolute, Mati Therapeutics) provides precisely controlled medication release into the tear film and has been associated with positive results in initial clinical testing.
New dry eye treatment demonstrates rapid onset symptomatic reliefResults from the Phase 3 OPUS-3 trial provide evidence confirming a benefit of lifitegrast ophthalmic solution 5.0% (Xiidra, Shire) for significantly improving dry eye disease-related symptoms, as measured by Eye Dryness Score.
Vectored thermal pulsation delivers long-lasting MGD improvementFollow-up from a study enrolling 200 patients with meibomian gland dysfuction showed a single treatment with vectored thermal pulsation afforded improvements in symptoms and meibomian gland function.
Semifluorinated alkane technology brings advantages for topical therapySemifluorinated alkane technology has novel physicochemical properties that explain its benefits as an ocular lubricant and support its use for developing a well-tolerated, preservative-free, multidose preparation of cyclosporine.
Limbal stem cell deficiency: Which procedure, whenCornea experts discuss the roles of ocular surface transplantation and keratoprosthesis implantation in the management of eyes with severe limbal stem cell deficiency.