A 59-year-old otherwise healthy man presented with an acute-onset diffuse rash involving over 90% of his body surface area, including oral, genital, and ocular mucosal involvement. Initial ophthalmic examination was notable for development of extensive corneal epithelial defects in both eyes as well as conjunctival sloughing and pseudomembrane formation.
Isolated Bowman layer transplantation can reduce and stabilize corneal ectasia in eyes with progressive advanced keratoconus, researchers said. “It flattens the cornea into a more normal position,” said Jack Parker, MD, a researcher at the Netherlands Institute for Innovative Ocular Surgery (NIIOS) in Rotterdam, The Netherlands. “It doesn’t give them perfect vision, but it keeps them from getting worse. It lets them to continue wearing their contact lenses.”
Analyses of data from 293 eyes undergoing uncomplicated Descemet membrane endothelial keratoplasty (DMEK) show that endothelial cell loss is greater in eyes that undergo a single re-bubbling for graft separation. The study, however, does not establish a causal association.
Results from the Phase 3 OPUS-3 trial provide evidence confirming a benefit of lifitegrast ophthalmic solution 5.0% (Xiidra, Shire) for significantly improving dry eye disease-related symptoms, as measured by Eye Dryness Score.
Under the best of circumstances—meaning when cataract surgery is performed in an eye with a normal cornea by expert hands and with use of an advanced IOL power calculation formula—the achieved refractive outcome will be more than 0.5 D off target in 1 out of every 11 eyes.