2017 American Academy of Ophthalmology meeting

Investigational IOL demonstrates true accommodationFindings from a pilot study show that a novel accommodative intraocular lens (AIOL, Lumina, Akkolens) provides a true accommodative response that is maintained for at least 2 years and preserved following Nd:YAG laser capsulotomy.
Plasma-free VEGF level decreases with aflibercept, bevacizumabCompared with intravitreous ranibizumab, the decreases in the plasma-free VEGF levels were greater with intravitreous aflibercept and bevacizumab in patients with diabetic macular edema.
Wider field of view does improve visualization of retinal vascular diseasesMost commercially available OCT and OCTA devices can provide widefield OCTA through a combination of faster speeds, tracking, and the ability to montage images. This may revolutionize clinicians’ ability to assess and quantify retinal vascular disease.
The time has come for gene therapy to treat retinal disease, AMDWith the first ocular gene therapy approved in the United States, Szilard Kiss, MD, points out that the gene therapy era for retinal disease has arrived, “and hopefully it will arrive for age-related macular degeneration.”
PALADIN subset finds improvement after 12 months with intravitreal implantAmong a subset of patients in the phase IV PALADIN study, there was improved visual acuity, improved macular thickness, and reduced treatment burden among patients treated with the intravitreal fluocinolone acetonide 0.2 µg (Iluvien implant) for DME.
Intraop wavefront aberrometry may enhance results in toric IOL surgeryFindings of a study determining the prediction error in the magnitude of residual astigmatism after cataract surgery with a toric intraocular lens (IOL) suggest that use of intraoperative wavefront aberrometry for toric power selection could enhance the refractive outcome in a large subset of eyes.
‘Hypersonic’ vitrectomy overcomes flaws of traditional systemsUsing ultrasonic power to actuate a vitrectomy probe (hypersonic vitrectomy) allows for a “smooth steady flow of vitreous into a port that is oscillating at 1.7 million cycles per minute,” according to Carl C. Awh, MD.
Drug delivery systems could improve poor adherenceJonathan S. Myers, MD, reports that intraocular drug delivery systems could help solve the problem of poor adherence in patients taking glaucoma medications. Implanted in the eye, the systems would allow for glaucoma drugs to gradually dissolve or elute medication.
Latest tonometry devices all have their pluses and minusesYvonne Buys, MD, says ophthalmologists can choose from a range of the latest devices for measuring IOP, each with its own strengths and weaknesses. While new technology continues to emerge, Dr. Buys provides an overview of tonometer technology.
Aflibercept shows macular perfusion gains in VISTA subanalysisThe use of aflibercept led to greater improvement in macular perfusion status in a phase III trial with DME patients. Those with baseline nonperfusion tended to have more advanced disease.