ModernMedicine Resource Center More Topics


Sulcus-to-sulcus suture technique offers solution for silicone oil use in aphakic eyes with iris loss

Retention sutures placed sulcus-to-sulcus in the iris plane are effective for keeping the silicone oil out of the anterior chamber.

Retina Treatments

Integrin peptide trials continue for wet AMD, DME, other pathologiesThe first drug in the new class integrin peptide therapy continues to show continued efficacy and safety in various clinical trials.
Intravitreal bevacizumab: Improved vascular pattern after treatment in ROPAfter intravitreal bevacizumab injection in eyes with treatment requiring-retinopathy of prematurity, there was growth and maturation of retinal vessels, although certain abnormalities remained.
Ranibizumab achieves higher BCVA gains for BRVO in COMRADE-BIn this article, Dr Simon Taylor discusses results of the key studies for both the ranibizumab anti-VEGF injection and the dexamethasone implant, including the higher BCVA gains achieved for BRVO with ranibizumab in COMRADE-B.
Lasting effects of anti-VEGF/photodynamic therapy for AMDThe authors present results from a retrospective chart review demonstrating effective management of exudative AMD using anti-VEGF/photodynamic combination therapy. Possible implications of these findings for clinical practice are also discussed.
Real-world experience: Positive DME treatment outcomes observed with FAc implant at UK centreDr Mushtaq discusses one centre’s initial post-marketing experience with the fluocinolone acetonide intravitreal implant 0.19 mg. The implant demonstrated favourable outcomes and good patient acceptance.
Real-world experience: Case study shows maintained benefits with FAc in DME patientIn the case study discussed in this article, a patient who was treated for DME with a fluocinolone acetonide intravitreal implant reported improved vision-related quality of life and the ability to perform daily routines without problems. These benefits persisted 12-months after treatment.
Dexamethasone for DME shows stronger results compared with sham groupIn this article Dr Anat Lowenstein explains that the benefits of treatment with a dexamethasone intravitreal implant for DME were observed across a variety of demographic characteristics.
Optos’ next-generation UWF device expands imaging modalityOptos’ next-generation, ultra-widefield (UWF) imaging platform (California) provides greater imaging functionality and introduces the company’s newest imaging modality—indocyanine green angiography (ICG) while maintaining all current color imaging modalities, autofluorescence (AF) and fluorescein angiography (FA).
Retinal gene therapy advancing into clinical realityGene therapy can provide transformative disease-modifying effects, with potentially lifelong clinical benefits after a single therapeutic administration. The most advanced retinal gene therapy program in the United States is in phase III study.
Intravitreal sirolimus shows promise for noninfectious posterior segment uveitisSAKURA is a 24-month phase III study investigating the efficacy and safety of intravitreal sirolimus for treatment of noninfectious posterior segment uveitis. Data were reported from the primary endpoint visit at 5 months.