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Sulcus-to-sulcus suture technique offers solution for silicone oil use in aphakic eyes with iris loss

Retention sutures placed sulcus-to-sulcus in the iris plane are effective for keeping the silicone oil out of the anterior chamber.

Retina Treatments

Squalamine for AMD ‘robust’ in eyes containing CNV lesionsCombination treatment with squalamine lactate ophthalmic solution 0.2% and ranibizumab PRN resulted in improved visual function in patients with neovascular age-related macular degeneration compared with treatment with ranibizumab alone.
Trophic factor replacement targets most debilitating effects of RPDegeneration of rods in eyes with RP leads to night vision problems and loss of rod-derived cone viability factor (RdCVF) that is necessary for cone survival. Replacing RdCVF may prevent cone degeneration and loss of central vision.
Novel anti-VEGF agent may provide important advancement in AMD treatmentA novel anti-vascular endothelial growth factor agent, RTH258, produced rapid and sustained improvements in visual acuity and central subfield thickness and was non-inferior to aflibercept in a phase II trial.
Bone marrow cells show promise in degenerative, ischemic retinal diseasesThe safety and feasibility of intravitreal autologous CD34+ bone marrow cells as a potential therapy for retinal disease were evaluated in a pilot study. Preliminary findings demonstrated the treatment was feasible and researchers intend to pursue a larger, prospective study with longer follow-up.
Subretinal implant yields meaningful benefits for retinitis pigmentosaOne-year outcomes with a subretinal implant for patients blinded by retinitis pigmentosa demonstrated a marked improvement in visual capabilities.
Pars plana vitrectomy makes paradigm shift for retinal surgery in EuropeEuropean retinal surgeons have been shifting to the use of pars plana vitrectomy for the repair of rhegmatogenous retinal detachment, but scleral buckle surgery is still a viable choice in young and uncomplicated cases.
Integrin peptide trials continue for wet AMD, DME, other pathologiesThe first drug in the new class integrin peptide therapy continues to show continued efficacy and safety in various clinical trials.
Intravitreal bevacizumab: Improved vascular pattern after treatment in ROPAfter intravitreal bevacizumab injection in eyes with treatment requiring-retinopathy of prematurity, there was growth and maturation of retinal vessels, although certain abnormalities remained.
Ranibizumab achieves higher BCVA gains for BRVO in COMRADE-BIn this article, Dr Simon Taylor discusses results of the key studies for both the ranibizumab anti-VEGF injection and the dexamethasone implant, including the higher BCVA gains achieved for BRVO with ranibizumab in COMRADE-B.
Lasting effects of anti-VEGF/photodynamic therapy for AMDThe authors present results from a retrospective chart review demonstrating effective management of exudative AMD using anti-VEGF/photodynamic combination therapy. Possible implications of these findings for clinical practice are also discussed.