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Sulcus-to-sulcus suture technique offers solution for silicone oil use in aphakic eyes with iris loss

Retention sutures placed sulcus-to-sulcus in the iris plane are effective for keeping the silicone oil out of the anterior chamber.

Retina Treatments

The AAO's preferred practice patterns for AMDHigh-level evidence supports the use of anti-vascular endothelial growth factor (VEGF) therapy for neovascular age-related macular degeneration (AMD), but falls short of recommending any one agent over another in terms of efficacy or safety, said Paul Sternberg Jr., MD.
Lesion size plays key role in squalamine eye drops therapySqualamine lactate—when combined with ranibizumab for treating neovascular age-related macular degeneration—achieved improved visual function when compared with the results achieved with ranibizumab treatment alone.
Surgical gene therapy study for wet AMD yields mixed resultsIn a phase IIa study of patients with neovascular age-related macular degeneration, a single subretinal injection of rAAV.sFlt-1 gene therapy demonstrated acceptable safety, but not a complete or durable anti-VEGF response. Additional preclinical research is under way.
Steroids may be preferable to anti-VEGF for DME in certain casesTwo-year study results highlight some advantages of steroid treatment for DME.
New instruments, devices improve safety and speed in vitreoretinal surgeryDavid R. Chow, MD, provides an overview of new technological advancements for the vitreoretinal surgeon.
Investigational pipeline for DME looks promisingPharmacotherapy research for diabetic macular edema is looking at targets other than VEGF inhibition to develop treatments that can be used as standalone intervention or may be complementary to current options.
Gene therapy for wet AMD shows promising long-term resultsThree-year follow-up from the phase I/IIa trial of rAAV.sFlt-1 subretinal injection is encouraging for gene therapy for exudative age-related macular degeneration.
Entry wound complications: Unexpected entry site hemorrhage proved difficult to manageUsing valved cannulas during phacovitrectomy is highly recommended when an unexpected site hemorrhage becomes difficult to manage.
Year brings advances in retinal imaging, screening, and gene/drug therapiesThe topics of special interest to retina specialists during 2015 include optical coherence tomography angiography (OCTA) and screening for retinopathy of prematurity (ROP). Important research is taking place to determine the etiology of angiogenesis, possibly leading to targeting therapies in age-related macular degeneration (AMD), ROP, and diabetic retinopathy.
DRCR.net retinal treatment results take center stage in 2015Studies of the efficacy of anti-vascular endothelial growth factor (VEGF), gene therapies, and slow-release drug delivery systems took center stage among treatments for retinal disorders in 2015. In addition to studies already under way, others are about to begin.