| Aspirin should be used to treat patients with acute MI and continued indefinitely to reduce vascular death, nonfatal MI, and nonfatal stroke. Clopidogrel added to aspirin is beneficial in the treatment of patients with acute ST-elevation MI. Patients with unstable angina or non-ST-elevation MI should be treated with aspirin plus clopidogrel for at least 9 months to reduce the risk of vascular death, nonfatal MI, and nonfatal stroke. Patients with prior MI should be treated indefinitely with aspirin. If aspirin is contraindicated, patients with prior MI should be treated indefinitely with clopidogrel. Patients with ischemic stroke should be treated with either aspirin or clopidogrel indefinitely. Extended-release dipyridamole plus low-dose aspirin is more efficacious than low-dose aspirin alone for stroke reduction but is associated with an insignificant increase in nonfatal MI and vascular death compared with low-dose aspirin. Clopidogrel is more effective than aspirin in reducing the risk of vascular.. |
Stroke
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