Retinal Disease

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Anti-vascular endothelial growth factor monotherapy useful option in patients with retinal angiomatous proliferation, study finds

Anti-vascular endothelial growth factor monotherapy appears to be an effective treatment for retinal angiomatous proliferation, according to results of a small, retrospective chart review. Although the results indicate that in most cases repeated injections would be needed to achieve improvement or stable vision, treatment based on ocular coherence tomography-confirmed presence of fluid could achieve outcomes similar to monthly injections.

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Diabetic macular edema responds to ranibizumab in study

Diabetic macular edema responds to treatment with ranibizumab (Lucentis, Genentech), according to results of the RESOLVE study. The patient responses to the drug in the changes in the visual acuity and central macular thickness were significantly better in the groups treated with two concentrations of ranibizumab compared with the sham-treated group.

Anti-vascular endothelial growth factor monotherapy useful option in patients with retinal angiomatous proliferation, study finds

E10030, ranibizumab have biologic activity against choroidal neovascularization in wet age-related macular degeneration, results show

In a phase I study, E10030 (Ophthotech) combined with ranibizumab (Lucentis, Genentech) in patients with subfoveal neovascular age-related macular degeneration was well tolerated and seemed to have biologic activity against choroidal neovascularization, according to one ophthalmologist.

When treating diabetic macular edema, focal/grid photocoagulation more effective than intravitreal triamcinolone, results show

Intravitreal triamcinolone (IVTA) for treating diabetic macular edema (DME) does not seem to be beneficial over the long term compared with focal/grid photocoagulation, and treatment with IVTA results in a higher chance of developing a cataract compared with treatment with the laser, according to a 3-year comparison study. Focal/grid photocoagulation, therefore, remains the most effective treatment for DME, according to one ophthalmologist.

Oral fenretinide may slow, halt geographic atrophy in those with age-related macular degeneration

Oral fenretinide given once daily may slow the progression of geographic atrophy in patients with age-related macular degeneration, according to an interim analysis.