Psoriasis - ModernMedicine

Psoriasis

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Treatment Found to Reduce Depression in Psoriasis
Treating psoriasis patients with adalimumab is associated with reduced depression and improved quality of life compared to placebo, according to research published in the May issue of the Journal of the American Academy of Dermatology.
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Biologic agents relieve chronic skin conditions where other treatments fail
Biologic therapies can help patients with dermatologic conditions, providing anti-inflammatory benefits without significant effects on other organ systems, says Steven R. Feldman, M.D., Ph.D., professor of dermatology, pathology and public health sciences, Wake Forest Baptist Medical Center, Winston-Salem, N.C.
Safety profile of biologics evolves, but long-term risk concerns remain
New safety profile data continues to emerge on biologics used in psoriasis. Among the findings: Today's biologics do not appear to increase serious infection risk; the drugs' short-term cancer risk profile is promising; but concerns remain about long-term cancer risk with all biologics and cardiovascular risk with interleukin-12/23, ustekinumab (Stelara, Janssen Biotech).
Clinicians concerned about safety, efficacy of biosimilar drugs
Biosimilars are designed to mimic biologic agents, but they are not precise duplicates of these drugs. Biosimilars may prove useful for treating skin conditions such as psoriasis, but clinicians are waiting for guidance on the drugs from the Food and Drug Administration, which was still pending at press time.
Harvard derm delves into origin of pruritus, adding to long list of accomplishments
Born into an accomplished dermatology family, Ethan Lerner, M.D., has had to ask himself if he had any choice but to join the specialty. His father, the late Aaron B. Lerner, M.D., former professor and chairman of the Yale University dermatology department, discovered melatonin and developed transplantation therapy for vitiligo.
Biologics' potential for side effects calls for thorough patient medical history, prescreening
Biologics may provide excellent relief from psoriasis, but that relief comes with the potential for serious side effects, mainly associated with an altered immune system. As a result, Kevin Cooper, M.D., emphasizes the importance of making sure patients are physically and mentally prepared for undergoing biologic therapies.
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