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Childbearing Shown to Increase Risk of Metabolic Syndrome Publish date: Aug 17, 2009  MONDAY, Aug. 17 (HealthDay News) -- Childbearing increases the likelihood of developing the metabolic syndrome, regardless
of whether women develop gestational diabetes mellitus (GDM), according to a study in the August issue of the American
Journal of Obstetrics & Gynecology. Erica P. Gunderson, Ph.D., from Kaiser Permanente Northern California in Oakland, and colleagues studied 1,451 women (18
to 30 years old) who had never given birth and followed them for 20 years. Women were classified based on whether they developed
GDM: 0 births, 1 non-GDM birth, 2+ non-GDM births, or 1+ GDM births. The researchers identified 259 incident cases of the metabolic syndrome. Compared with no births, increasing numbers of
births were associated with a higher risk of developing the metabolic syndrome. The adjusted relative hazard ratios were 1.33
for 1 non-GDM birth, 1.62 for 2+ non-GDM births, and 2.43 for 1+ GDM births. "Our findings suggest that childbearing contributes to development of the metabolic syndrome and that the association is
partially mediated through weight gain and lack of physical activity," Gunderson and colleagues conclude. "Although women
with GDM had the highest relative risk, those with non-GDM pregnancies had a greater absolute risk, contributing four times
as many cases as GDM pregnancies (40 versus 9 percent metabolic syndrome cases)." Copyright © 2009 ScoutNews, LLC. All rights reserved. | Featured Jobs Practice Tools Coding Counselor Simple and accurate ICD-9 code search. Start Here  Patient Education Print customized patient education handouts. Start Here  Dermatology Diagnosis Identify skin diseases by age, gender, location. Start Here  AHRQ Clinical Guidelines Objective findings on medical interventions. Start Here     |
