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Clinical Pharmacology

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Erectile dysfunction and premature ejaculation: underlying causes and available treatments
This review examines the underlying causes associated with ED and PE and evaluates currently available treatment options and those under investigation.
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Golimumab shows robust effect for inhibiting arthritic joint damage
The first data from radiologic analyses in the phase 3 clinical trial of golimumab (Simponi, Centocor Ortho Biotech) for treatment of active psoriatic arthritis demonstrate the benefit of this new anti-TNF-alpha agent for inhibiting joint damage.
Erectile dysfunction and premature ejaculation: underlying causes and available treatments
This review examines the underlying causes associated with ED and PE and evaluates currently available treatment options and those under investigation.
Roflumilast: A new phosphodiesterase 4 inhibitor for chronic obstructive pulmonary disease
Roflumilast is a novel, orally active phosphodiesterase 4 inhibitor currently under review by FDA for the treatment of patients with moderate-to-severe COPD.
Diclofenac sodium topical solution (Pennsaid): Nonsteroidal anti-inflammatory topical solution approved for chronic management of knee osteoarthritis
New formulation: Diclofenac sodium topical solution (Pennsaid) was approved on November 5, 2009, to treat the signs and symptoms of osteoarthritis of the knee.
Pralatrexate injection (Folotyn): Folate analogue metabolic inhibitor approved for treatment of relapsed or refractory peripheral T-cell lymphoma
New molecular entity: Pralatrexate injection (Folotyn) was approved on September 24, 2009, for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma.
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