http://www.modernmedicine.com/modernmedicine/Corneal+Disease/Article/list/46496 Visit ModernMedicine.com, a medical resource for physicians, to find coding and formulary tools, free CME, patient education, medical news and articles, and more. 2009-11-21T22:27:46Z http://www.modernmedicine.com/modernmedicine/Retinal+Disease/Cataract-Surgery-Unlikely-to-Affect-the-Progressio/ArticleNewsFeed/Article/detail/642025?contextCategoryId=46496&ref=25 In patients with non-neovascular age-related macular degeneration (AMD), cataract surgery is not associated with an increased risk of AMD progression. In addition, dietary fats may have differential effects on the risk of AMD, according to two studies in the November issue of the Archives of Ophthalmology. 2009-11-16T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/472009/642025/SS36006.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/472009/642025null XML http://www.modernmedicine.com/modernmedicine/Clinical+News/FDA-approves-Sirions-NDA-for-ganciclovir-015-for-h/ArticleStandard/Article/detail/631228?contextCategoryId=46496&ref=25 The FDA has approved a new drug application (NDA) for ganciclovir ophthalmic gel 0.15% (Zirgan, Sirion Therapeutics) as a treatment for acute herpetic keratitis (dendritic ulcers), the company announced. 2009-10-02T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/412009/631228null HTML http://www.modernmedicine.com/modernmedicine/Nursing/Childhood-Nephrotic-Syndrome-Can-Cause-Lifelong-Il/ArticleNewsFeed/Article/detail/629418?contextCategoryId=46496&ref=25 Children with minimal-change nephrotic syndrome are at increased risk for osteoporosis, hypertension, sperm abnormalities and cataracts if the condition persists beyond puberty, according to a study published online Sept. 24 in the Clinical Journal of the American Society of Nephrology. 2009-09-25T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/392009/629418/kidney2.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/392009/629418null XML http://www.modernmedicine.com/modernmedicine/Clinical+News/DSEK-shown-to-be-safe-effective-therapy-according-/ArticleStandard/Article/detail/624925?contextCategoryId=46496&ref=25 Descemet's stripping endothelial Keratoplasty (DSEK) was shown to be a safe and effective treatment for corneal endothelial diseases, according to a 2009 review by the cornea panel of the American Academy of Ophthalmology's (AAO) Ophthalmic Technology Assessment Committee, led by W. Barry Lee, MD. 2009-09-08T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/372009/624925null HTML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Study-Sodium-hyaluronate-solution-safe-effective/ArticleStandard/Article/detail/627671?contextCategoryId=46496&ref=25 An investigational compound for the treatment of dry eye disease consisting of a proprietary formulation of sodium hyaluronate ophthalmic solution 0.18% (Vismed, Lantibio Inc.) was shown to be safe and effective in a multicenter phase III trial conducted in the United States. A new drug application has been filed for the solution, which is already marketed in parts of Europe and Asia as a viscoelastic lubricant eye drop. 2009-09-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/382009/627671null XML http://www.modernmedicine.com/modernmedicine/Endocrinology/Cataract-Surgery-Associated-With-Diabetic-Eye-Prob/ArticleNewsFeed/Article/detail/617424?contextCategoryId=46496&ref=25 Phacoemulsification surgery for cataracts in patients with diabetes is associated with higher rates of new or progressing diabetic retinopathy in the following year, according to research published in the August issue of Ophthalmology. 2009-08-06T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/322009/617424/eyechart_59082.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/322009/617424null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Low-IOP-is-measured-with-great-accuracy-using-non-/ArticleStandard/Article/detail/617069?contextCategoryId=46496&ref=25 A non-contact applanation tonometer (Ocular Response Analyzer, Reichert) appears to be more effective than the Goldmann applanation tonometer (GAT) in assessing very low and negative IOP values using the non-contact applanation tonometer's corneal-compensated IOP (IOPcc) parameter. The GAT may be the long-accepted gold standard, but the more accurate assessment of IOP using the non-contact applanation tonometer challenges this gold standard and raises questions as to which of the two techniques is optimal in measuring IOP. 2009-08-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/322009/617069null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Antihypertensive-Drugs-Associated-With-Cataracts/ArticleNewsFeed/Article/detail/613458?contextCategoryId=46496&ref=25 Patients treated with beta blockers for hypertension are more likely than their counterparts not using the drugs to develop cataracts and require cataract surgery, according to a study published online July 23 in the British Journal of Ophthalmology. 2009-07-23T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/302009/613458/eye_SS36015.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/302009/613458null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Post-LASIK-healing-rate-may-be-increased-by-hyprom/ArticleStandard/Article/detail/610905?contextCategoryId=46496&ref=25 Hypromellose 0.3% gel (GenTeal Gel, Novartis Ophthalmics) may increase the rate of re-epithelialization of the gutter around LASIK flaps during the first postoperative week. 2009-07-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/292009/610905null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Patients-with-dry-eye-find-symptom-relief-quality-/ArticleStandard/Article/detail/610903?contextCategoryId=46496&ref=25 Use of a proprietary hydroxypropyl cellulose ophthalmic insert (Lacrisert, Aton Pharma) in patients with dry eye syndrome can improve dry eye symptoms and significantly improve the quality of life for these patients, according to a recent study. 2009-07-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/292009/610903null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/When-using-punctal-plugs-for-dry-eye-surgeon-favor/ArticleStandard/Article/detail/610889?contextCategoryId=46496&ref=25 When faced with a decision about which type of punctal plug to use in the management of dry eye, one oculofacial plastic surgeon said she turns to traditional occluders made of silicone because they have a long track record and are easily visualized for removal, if necessary. She has not used intracanalicular plugs made of polyglycolic acid or hydrogel but said they seem promising. 2009-07-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/292009/610889null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Osmometer-comparison-shows-newer-technology-allows/ArticleStandard/Article/detail/610893?contextCategoryId=46496&ref=25 A head-to-head comparison of an older nanoliter osmometer (Clifton Technical Physics) and a newer osmometer (OcuSense) shows that both devices are effective in measuring tear osmolarity and produce comparable measurements. The newer device has great potential for office clinical use, because readings can be taken very easily and quickly by a non-trained individual, according to one doctor. 2009-07-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/292009/610893null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Artificial-tear-product-improves-functional-visual/ArticleStandard/Article/detail/610896?contextCategoryId=46496&ref=25 An evaluation of functional visual performance of two currently marketed artificial tear products using the interblink interval visual acuity decay method showed that a tear with a polyethylene glycol/propylene glycol (PEG/PG)-based formulation (Systane Ultra, Alcon Laboratories) resulted in a statistically significant increase in the length of time within one line of best-corrected visual acuity (BCVA) within an interblink period at 90 minutes after instillation of a single drop. The drop was compared with a carboxymethylcellulose/glycerin-based tear (Optive, Allergan). Median times to one-line loss of BCVA were not statistically different at the timepoints of 15 or 45 minutes post-instillation. 2009-07-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/292009/610896null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Eye-drop-formulation-found-effective-for-post-LASI/ArticleStandard/Article/detail/610897?contextCategoryId=46496&ref=25 Optive Sensitive (Allergan) was safe and effective for the management of dry eye signs and symptoms after LASIK surgery and may have some incremental benefits over standard tear management. 2009-07-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/292009/610897null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Intraductal-meibomian-gland-probing-reduces-inflam/ArticleStandard/Article/detail/610890?contextCategoryId=46496&ref=25 A new technique of intraductal meibomian gland probing using disposable cannulas of various lengths appears highly effective in providing quick and lasting relief from inflammatory symptoms of obstructive meibomian gland disease. 2009-07-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/292009/610890null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/PostLASIK-dry-eye-treatment-using-sodium-hyalurona/ArticleStandard/Article/detail/610904?contextCategoryId=46496&ref=25 The benefits of two artificial tear products were compared in a head-to-head, randomized, contralateral eye-controlled study enrolling 40 patients undergoing bilateral LASIK. Wavefront analysis was used for the primary outcome assessment of quality of vision and favored use of a sodium hyaluronate-based product (Blink Tears, Abbott Medical Optics). 2009-07-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/292009/610904null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Lid-wiper-epitheliopathy-Oil-in-water-emulsion-mai/ArticleStandard/Article/detail/610906?contextCategoryId=46496&ref=25 An oil-in-water emulsion and a corticosteroid both were effective in eliminating the signs and symptoms of lid wiper epitheliopathy after a 1-month active treatment phase in a recent study. 2009-07-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/292009/610906null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Allergic-conjunctivitis-efficacy-of-olopatadine-02/ArticleStandard/Article/detail/610894?contextCategoryId=46496&ref=25 Olopatadine hydrochloride 0.2% ophthalmic solution (Pataday, Alcon Laboratories), an antihistamine/mast cell stabilizer, is highly effective for treating allergic conjunctivitis, according to two clinicians who spoke with Ophthalmology Times. 2009-07-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/292009/610894null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Epinastine-HCl-shows-utility-in-dry-eye-allergy/ArticleStandard/Article/detail/610895?contextCategoryId=46496&ref=25 Dry eye disease is a common concomitant finding in patients with allergic conjunctivitis. Treatment selection can be challenging because some anti-allergy agents with antihistaminic activity can cause ocular surface drying. 2009-07-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/292009/610895null XML http://www.modernmedicine.com/modernmedicine/Industry+News/Dr-Alfonso-named-chairman-at-Bascom-Palmer/ArticleStandard/Article/detail/610826?contextCategoryId=46496&ref=25 Eduardo C. Alfonso, MD, has been named chairman of the Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, according to a prepared statement. 2009-07-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/292009/610826null HTML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Dry-eye-progression-prevented-by-cyclosporine/ArticleStandard/Article/detail/610891?contextCategoryId=46496&ref=25 A recent study showed that moderate to severe dry eye disease can be best treated with anti-inflammatory medications such as topical cyclosporine. According to one ophthalmologist, cyclosporine can significantly limit progression of dry eye disease and should be considered a "go-to" therapy in this patient population. 2009-07-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/292009/610891null XML http://www.modernmedicine.com/modernmedicine/Cornea/Bascom-Palmer-names-Eduardo-C-Alfonso-MD-its-new-c/ArticleStandard/Article/detail/608859?contextCategoryId=46496&ref=25 Eduardo C. Alfonso, MD, is the new chairman of the Bascom Palmer Eye Institute, University of Miami Miller School of Medicine. Dr. Alfonso is the fifth chairman to be named in the institute's 47-year history. 2009-07-06T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/282009/608859null HTML http://www.modernmedicine.com/modernmedicine/Clinical+News/Corneal-edema-patients-at-higher-risk-for-transpla/ArticleStandard/Article/detail/601688?contextCategoryId=46496&ref=25 The corneal transplant failure rate was four times higher in patients diagnosed with corneal edema associated with either IOL implants or no natural lens following cataract removal, than in patients diagnosed with Fuchs' dystrophy, according to a study. 2009-06-04T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/232009/601688null HTML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Besifloxacin-effective-against-corneal-bacteria/ArticleStandard/Article/detail/603258?contextCategoryId=46496&ref=25 Besifloxacin (Optura, Bausch & Lomb) was found to be more effective than gatifloxacin and moxifloxacin in reducing the number of methicillin-resistant Staphylococcus aureus organisms in the cornea when applied topically 10 to 18 hours after infection. 2009-06-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/242009/603258null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Tonometry-measurements-characterize-changes-in-ker/ArticleStandard/Article/detail/597247?contextCategoryId=46496&ref=25 Results of a study using a non-contact applanation tonometer (Ocular Response Analyzer, Reichert) to evaluate keratoconic eyes during and after corneal collagen crosslinking demonstrate changes in tonometer measurements that are consistent with changes in corneal thickness, hydration, and regularity. 2009-04-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/192009/597247null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Donor-death-surgery-interval-may-affect-DSAEK-outc/ArticleStandard/Article/detail/597244?contextCategoryId=46496&ref=25 Data analyzed from a total of 568 eyes included in a prospective study of Descemet's stripping automated endothelial keratoplasty indicate that the time from donor death to surgery affects endothelial cell density loss and risk of graft dislocation, but more data are needed to understand possible associations better. 2009-04-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/192009/597244null XML http://www.modernmedicine.com/modernmedicine/Clinical+News/ASCRS-Scheimpflug-device-ultrasound-pachymetry-bot/ArticleStandard/Article/detail/591753?contextCategoryId=46496&ref=25 San Francisco—Both ultrasound pachymetry and a proprietary Scheimpflug imaging device (Galilei Dual Scheimpflug Analyzer, Ziemer Ophthalmic Systems) produced excellent repeatability of central corneal thickness (CCT) measurements, and the repeatability was strong for both "virgin" and post-refractive eyes, according to Mitchell P. Weikert, MD, MS, assistant professor of ophthalmology, Baylor College of Medicine, Houston. 2009-04-05T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/152009/591753null HTML http://www.modernmedicine.com/modernmedicine/Clinical+News/ASCRS-Novel-pachymetric-map-analysis-detects-kerat/ArticleStandard/Article/detail/591754?contextCategoryId=46496&ref=25 San Francisco—Gaussian fitting on inverse normalized pachymetry maps enables quantification of the depth and width of focal thinning associated with keratoconus and is showing promise as a new method for diagnosing this corneal ectatic disease, said David Huang, MD, PhD, of the University of Southern California, Los Angeles. 2009-04-05T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/152009/591754null HTML http://www.modernmedicine.com/modernmedicine/Clinical+News/ASCRS-Air-bubble-injection-may-be-a-source-of-endo/ArticleStandard/Article/detail/591749?contextCategoryId=46496&ref=25 San Francisco—Results of a study using an ex vivo model suggest a possible role for air bubble-induced trauma in loss of endothelial cell density after Descemet's stripping automated endothelial keratoplasty (DSAEK), said Anna Hong, MD, a resident at the Duke University Eye Center, Durham, NC. 2009-04-05T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/152009/591749null HTML http://www.modernmedicine.com/modernmedicine/Clinical+News/ASCRS-FDA-trial-data-positive-for-corneal-collagen/ArticleStandard/Article/detail/591528?contextCategoryId=46496&ref=25 San Francisco—An interim analysis of data from an ongoing U.S. clinical trial shows corneal collagen crosslinking using riboflavin and ultraviolet A (UVA) light has promising efficacy and safety for the treatment of progressive keratoconus and postLASIK ectasia, said R. Doyle Stulting, MD, PhD, professor of ophthalmology, Emory University, Atlanta. 2009-04-03T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/142009/591528null HTML http://www.modernmedicine.com/modernmedicine/Clinical+News/ASCRS-Femtosecond-laser-enables-PKP-but-not-all-ey/ArticleStandard/Article/detail/591527?contextCategoryId=46496&ref=25 San Francisco—Femtosecond laser-assisted penetrating keratoplasty (PKP) has potential advantages over conventional PKP performed with manual corneal trephination. 2009-04-03T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/142009/591527null HTML http://www.modernmedicine.com/modernmedicine/Clinical+News/ASCRS-Efficacy-safety-data-support-recommendation-/ArticleStandard/Article/detail/591526?contextCategoryId=46496&ref=25 San Francisco—In eyes with normal endothelium requiring corneal transplantation, deep anterior lamellar keratoplasty (DALK) using Anwar's big-bubble technique can result in visual acuity outcomes that are at least as good as those experienced after penetrating keratoplasty (PKP) and with the advantage of causing fewer complications than the full thickness procedure, said Donald H. Tan, MD, deputy director and head, corneal service, Singapore National Eye Centre, and head and professor of ophthalmology, National University of Singapore. 2009-04-03T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/142009/591526null HTML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Inhaled-and-Oral-Corticosteroid-Link-to-Cataracts-/ArticleNewsFeed/Article/detail/591521?contextCategoryId=46496&ref=25 Individuals who use both inhaled and oral corticosteroids may face increased long-term risks of posterior subcapsular cataracts and nuclear cataracts, according to research published in the April issue of Ophthalmology. 2009-04-03T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/142009/591521/eyechart.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/142009/591521null XML http://www.modernmedicine.com/modernmedicine/Clinical+News/ASCRS-Multiple-routes-of-administration-viable-for/ArticleStandard/Article/detail/591529?contextCategoryId=46496&ref=25 San Francisco—Although the debate continues regarding the pros and cons of different approaches to antibiotic prophylaxis for postoperative endophthalmitis, available data are clear in demonstrating that it is critical to assure an effective concentration is present at the time of surgery and maintained in the early postoperative period, said Randall J. Olson, MD, John A. Moran Presidential Professor and chairman of the Department of Ophthalmology and Visual Sciences, University of Utah School of Medicine, Salt Lake City. 2009-04-03T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/142009/591529null HTML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Most-recent-fluoroquinolones-bolster-antimicrobial/ArticleStandard/Article/detail/593676?contextCategoryId=46496&ref=25 Although the newest fluoroquinolones increasingly are used as the antimicrobial of choice for prophylaxis and treatment of serious ocular infections, they should not be relied on to treat established infections caused by methicillin-resistant Staphylococcus aureus, fluoroquinolone-resistant bacteria, or atypical Mycobacteria. Treatment of fungal ocular infections continues to be a challenge. 2009-04-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/162009/593676null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/RGN-259-promotes-healing-in-patients-with-non-heal/ArticleStandard/Article/detail/589243?contextCategoryId=46496&ref=25 An ophthalmic drug candidate based on the naturally occurring peptide thymosin beta 4 has been used to treat several patients with neurotrophic keratitis and non-healing ulcers under a compassionate use investigational new drug application. All of the ulcers healed completely or demonstrated significant improvement. The experimental drug, RGN-259 (RegeneRx Biopharmaceuticals Inc.), also could have potential in treating corneal wounds and related disorders. 2009-03-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/132009/589243null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Corneal-topography-stability-after-crosslinking-is/ArticleStandard/Article/detail/585650?contextCategoryId=46496&ref=25 Results from visual acuity testing, refraction, and corneal topography analysis using Scheimpflug imaging (Pentacam, Oculus) in a series of 48 eyes with progressive keratoconus demonstrate the benefits of corneal collagen crosslinking for halting keratoconus progression. More research is needed to provide answers to questions about the long-term stability of collagen corneal crosslinking and to refine its indications and contraindications. 2009-03-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/102009/585650null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/For-dry-eye-patients-punctal-plugs-offer-flow-cont/ArticleStandard/Article/detail/585651?contextCategoryId=46496&ref=25 Soft Plug Flow Control Silicone Plugs (Oasis Medical) provide partial occlusion of the puncta with limited tear drainage for patients with moderate and severe dry eye. These plugs eliminate epiphora in patients for whom total occlusion is excessive. 2009-03-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/102009/585651null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Meibomian-gland-disease-therapy-eased-by-kit/ArticleStandard/Article/detail/582494?contextCategoryId=46496&ref=25 A new product (NutriDox Convenience Kit, Advanced Vision Research) is designed to make the treatment of meibomitis, posterior blepharitis, and meibomian gland disease more convenient for patients and clinicians. The prescription-only system includes an antibiotic, nutrition therapy, and a lid-cleansing component. 2009-02-15T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/082009/582494null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Resident-Writers-Award-Femtosecond-laser-assisted-/ArticleStandard/Article/detail/577636?contextCategoryId=46496&ref=25 The femtosecond laser may be useful in the treatment of advanced fungal keratitis, according to this case presentation. 2009-01-15T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/052009/577636null XML http://www.modernmedicine.com/modernmedicine/Cornea+News/Eye-and-cornea-research-made-easier-by-two-antibod/ArticleStandard/Article/detail/571959?contextCategoryId=46496&ref=25 A global biotechnology company focused in inflammation and neurology research, announced the launch of two monoclonal antibodies (Lumican and Keratocan, MD Biosciences). 2008-12-16T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/512008/571959null HTML http://www.modernmedicine.com/modernmedicine/2008+AAO+News/AAO-Fellow-eye-study-finds-efficacy-and-benefits-f/ArticleStandard/Article/detail/564731?contextCategoryId=46496&ref=25 Results from a study evaluating the first photochromic IOL (Aurium, Medennium) indicate that it provides stable and effective pseudophakic correction and outperforms a yellow IOL under mesopic conditions, said David Mendez Noble, MD, Mexicali, Mexico. 2008-11-09T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/462008/564731null HTML http://www.modernmedicine.com/modernmedicine/Clinical+News/AAO-Next-generation-calcineurin-inhibitor-in-pivot/ArticleStandard/Article/detail/564674?contextCategoryId=46496&ref=25 Enrollment has been completed in a series of phase III studies investigating voclosporin (Lumeniq, Lux Biosciences) as a steroid-sparing agent for the treatment of noninfectious uveitis, according to Quan Dong Nguyen, MD, assistant professor of ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore. 2008-11-08T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/452008/564674null HTML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Web-links-pediatric-eye-conditions/ArticleStandard/Article/detail/564364?contextCategoryId=46496&ref=25 Links to useful Web sites about pediatric eye conditions. 2008-11-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/contpeds/452008/564364null XML http://www.modernmedicine.com/modernmedicine/Cornea+Feature/Intracameral-triamcinolone-may-be-viable-PKP-treat/ArticleStandard/Article/detail/560435?contextCategoryId=46496&ref=25 Topical, periocular, and/or systemic corticosteroids typically are used to treat corneal endothelial graft rejection. When those modalities fail, experience in a series of five eyes suggests intracameral triamcinolone acetonide may be worth considering. 2008-11-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/432008/560435null XML http://www.modernmedicine.com/modernmedicine/Cornea+Feature/Dry-eye-a-serious-public-health-problem/ArticleStandard/Article/detail/559861?contextCategoryId=46496&ref=25 Considerable progress has been made in recent years in the understanding of the epidemiology of dry eye disease. Here, two doctors discuss some of the studies that have helped ophthalmologists understand the prevalence, burden, and risk factors of dry eye disease. They also highlight how improved diagnosis will have a significant effect on the quality of life of patients with dry eye. 2008-10-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/432008/559861null XML http://www.modernmedicine.com/modernmedicine/Cornea+Feature/Artificial-cornea-useful-in-patients-with-multiple/ArticleStandard/Article/detail/556874?contextCategoryId=46496&ref=25 In patients who have suffered multiple immunologic graft rejections, the chance of providing good-quality vision is dramatically increased with a keratoprosthesis than another transplant. Patients who receive a keratoprosthesis have rapid visual return, a good quality of vision, and a high rate of graft survival. 2008-10-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/412008/556874null XML http://www.modernmedicine.com/modernmedicine/Clinical+News/ESCRS-Cross-linking-stability-remarkable/ArticleStandard/Article/detail/549900?contextCategoryId=46496&ref=25 Corneal crosslinking showed remarkable stability in a recent rabbit study, Dr Gregor Wollensak told delegates during the session on New Surgical Approaches to Keratoconus. 2008-09-13T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/382008/549900null HTML http://www.modernmedicine.com/modernmedicine/Corneal+Disease+Top+Story/Permanent-and-temporary-keratoprostheses-save-sigh/ArticleStandard/Article/detail/547264?contextCategoryId=46496&ref=25 Severely traumatized eyes may be salvaged with use of either a permanent or temporary keratoprosthesis. 2008-09-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/362008/547264null HTML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/sponsored-multimediaHigh-Performance-Dry-Eye-Thera/ArticleStandard/Article/detail/546382?contextCategoryId=46496&ref=25 2008-08-29T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/352008/546382null HTML http://www.modernmedicine.com/modernmedicine/Cornea+Feature/Riboflavin-and-UV-treatment-promotes-collagen-cros/ArticleStandard/Article/detail/544831?contextCategoryId=46496&ref=25 The combination of ultraviolet radiation and riboflavin treatment to achieve collagen cross-linking may be beneficial in biomechanical stabilization of ectasia, according to an expert who says the combined procedure has reduced the need for penetrating keratoplasty in his practice by 70%. 2008-08-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/352008/544831null XML http://www.modernmedicine.com/modernmedicine/Cornea/Vaccines-may-have-future-in-ocular-HZV-and-HPV/ArticleStandard/Article/detail/543117?contextCategoryId=46496&ref=25 Vaccines may have a role in corneal and external ocular disease, specifically for herpes zoster virus and human papilloma virus infections, because of the successes of the vaccines in preventing systemic diseases. 2008-08-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/342008/543117null HTML http://www.modernmedicine.com/modernmedicine/Cornea+Feature/Optical-coherence-tomography-a-useful-addition-to-/ArticleStandard/Article/detail/544820?contextCategoryId=46496&ref=25 A proprietary device for optical coherence tomography (Visante, Carl Zeiss Meditec) seems to be a highly useful addition to clinical practice. The instrument, according to one physician, may be the best resource thus far to evaluate placement of intracorneal segments, femtosecond laser-enabled keratoplasty, and penetrating keratoplasty. 2008-08-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/352008/544820null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/font-size-2sponsored-multimediafontbr-Allegretto-W/ArticleStandard/Article/detail/525199?contextCategoryId=46496&ref=25 2008-06-20T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/252008/525199null HTML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/font-size-2sponsored-multimediafontbr-Sub-Bowmans-/ArticleStandard/Article/detail/525203?contextCategoryId=46496&ref=25 2008-06-20T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/252008/525203null HTML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/font-size-2sponsored-multimediafontbr-Allegretto-W/ArticleStandard/Article/detail/525208?contextCategoryId=46496&ref=25 2008-06-20T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/252008/525208null HTML http://www.modernmedicine.com/modernmedicine/Cornea/Levofloxacin-15-safe-for-corneal-endothelium/ArticleStandard/Article/detail/522105?contextCategoryId=46496&ref=25 Levofloxacin ophthalmic solution 1.5% (Iquix, Vistakon Pharmaceuticals), used to treat bacterial keratitis, has no adverse effects on the corneal endothelium after 2 weeks of intensive dosing for a total of 224 doses of the drug. 2008-06-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/232008/522105null XML http://www.modernmedicine.com/modernmedicine/Cornea/New-artificial-cornea-research-could-promise-incre/ArticleStandard/Article/detail/519446?contextCategoryId=46496&ref=25 In an effort to make corneal transplants more available, researchers have designed an artificial cornea made from a water-filled polymer that resembles the eye's natural cornea. 2008-05-28T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/222008/519446null HTML http://www.modernmedicine.com/modernmedicine/Industry+News/UV-rays-dont-just-damage-skin/ArticleStandard/Article/detail/513870?contextCategoryId=46496&ref=25 Prevent Blindness has dedicated May as UV Awareness Month in an effort to educate the public on the best way to protect their eyes. 2008-05-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/182008/513870null HTML http://www.modernmedicine.com/modernmedicine/Cornea/Cyclosporine-beneficial-for-treating-patients-with/ArticleStandard/Article/detail/516488?contextCategoryId=46496&ref=25 Cyclosporine 0.05% ophthalmic emulsion (Restasis, Allergan) is beneficial for treating patients with dry eye because it increases goblet cell density and production of transforming growth factor ?2, an immunoregulatory factor, compared with artificial tear formulations, which do not. 2008-05-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/202008/516488null XML http://www.modernmedicine.com/modernmedicine/Cornea/Eye-drops-restore-and-maintain-ocular-surface-heal/ArticleStandard/Article/detail/516485?contextCategoryId=46496&ref=25 Multiple studies evaluating the effects of treatment with Systane Lubricant Eye Drops (Alcon Laboratories) on corneal staining in patients with dry eye disease demonstrate this novel artificial tear has benefits for improving ocular surface health. 2008-05-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/202008/516485null XML http://www.modernmedicine.com/modernmedicine/Cornea/Once-daily-insert-designed-to-provide-lasting-dry-/ArticleStandard/Article/detail/516487?contextCategoryId=46496&ref=25 A hydroxypropyl cellulose ophthalmic insert (Lacrisert, Aton Pharma) is a preservative-free product recommended for once-daily insertion in the inferior cul-de-sac. Its convenience, efficacy, and safety make it a valuable option for the management of dry eye disease. 2008-05-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/202008/516487null XML http://www.modernmedicine.com/modernmedicine/Cataract+News/IOL-technology-focuses-on-implant-orientation-rota/ArticleStandard/Article/detail/514663?contextCategoryId=46496&ref=25 A retrospective study of eyes with a spherical IOL implanted found the lens haptics maintained a stable position in most eyes, but significant rotation was observed in a small proportion. This information is important to consider when implanting toric IOLs where orientation and rotation can affect vision outcomes. 2008-05-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/192008/514663null HTML http://www.modernmedicine.com/modernmedicine/Cornea/Nanoparticle-offers-promise-for-treating-glaucoma/ArticleStandard/Article/detail/516482?contextCategoryId=46496&ref=25 A cerium oxide nanoparticle bound to a human carbonic anhydrase inhibitor (hCAII) has shown promise as a drug-delivery device for treating glaucoma. In a series of experiments, investigators attached hCAII to the nanoparticle and also attached a fluorophore so that they could confirm the attachment and track the particle's inhibitory effects. 2008-05-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/202008/516482null XML http://www.modernmedicine.com/modernmedicine/Cornea/New-tear-formulation-provides-additional-option-fo/ArticleStandard/Article/detail/516484?contextCategoryId=46496&ref=25 Carboxymethylcellulose 0.5% with compatible solutes (CMC-solutes) (Optive, Allergan), a new artificial tear formulation, when used with topical cyclosporine 0.05% (Restasis, Allergan) in patients with ocular surface disease, improved the objective signs and subjective symptoms of the disease when compared with the patients' previously used artificial tears. 2008-05-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/202008/516484null XML http://www.modernmedicine.com/modernmedicine/Cornea/Testing-platform-yields-point-of-care-osmolarity-m/ArticleStandard/Article/detail/516489?contextCategoryId=46496&ref=25 A tear-testing platform under development could revolutionize osmolarity testing by making it possible to conduct tests quickly and accurately in the practice setting using a small volume of tears. 2008-05-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/202008/516489null XML http://www.modernmedicine.com/modernmedicine/Cornea/Loteprednol-etabonate-provides-multiple-benefits-f/ArticleStandard/Article/detail/516486?contextCategoryId=46496&ref=25 When initiating treatment with topical cyclosporine ophthalmic emulsion 0.05% (Restasis, Allergan), adjunctive use of loteprednol etabonate ophthalmic suspension 0.5% (Lotemax, Bausch & Lomb) hastens and increases relief of dry eye signs and symptoms and reduces cyclosporine-associated burning and stinging without adding safety concerns, according to the results of a multicenter, randomized, controlled, masked trial comparing the combination regimen with cyclosporine plus artificial tears. 2008-05-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/202008/516486null XML http://www.modernmedicine.com/modernmedicine/Clinical+News/Old-and-young-cornea-donor-tissue-equally-effectiv/ArticleStandard/Article/detail/509405?contextCategoryId=46496&ref=25 University of Rochester researchers recently put to test the bias against corneas from older donors. 2008-04-10T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/152008/509405null HTML http://www.modernmedicine.com/modernmedicine/Cornea/Deep-anterior-lamellar-keratoplasty-yields-satisfa/ArticleStandard/Article/detail/506542?contextCategoryId=46496&ref=25 Deep anterior lamellar keratoplasty resulted in satisfactory best spectacle-corrected visual acuity levels after 18 months follow-up. The rate of graft clarity was almost 90% and the rate of stromal rejection was low. However, the rate of endothelial cell loss at 18 months postoperatively was high. 2008-04-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/142008/506542null XML http://www.modernmedicine.com/modernmedicine/Industry+News/Corneal-implants-okayed-for-use-in-Canada/ArticleStandard/Article/detail/506488?contextCategoryId=46496&ref=25 Addition Technology has received regulatory clearance from Health Canada to market its corneal implants (Intacs) for keratoconus and myopia indications. 2008-04-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/142008/506488null XML http://www.modernmedicine.com/modernmedicine/Cataract/Complication-risks-must-be-discussed-with-RLE-pati/ArticleStandard/Article/detail/505799?contextCategoryId=46496&ref=25 The informed consent for refractive lens exchange must apprise patients about the risks of endophthalmitis and rhegmatogenous retinal detachment. Data on these issues, which are mostly derived from the cataract surgery literature, are reviewed. 2008-03-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/132008/505799null XML http://www.modernmedicine.com/modernmedicine/Cataract/Accommodating-IOLs-new-design-shows-benefits/ArticleStandard/Article/detail/503975?contextCategoryId=46496&ref=25 Results of a multicenter FDA clinical trial of a fourth-generation version of an accommodating IOL (crystalens HD-100, eyeonics/Bausch & Lomb) demonstrate that the lens provides excellent uncorrected visual acuity at all distances that exceeds those of previous versions and without causing loss of contrast sensitivity. 2008-03-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/122008/503975null XML http://www.modernmedicine.com/modernmedicine/Cornea/Calculating-corneal-SA-can-influence-IOL-selection/ArticleStandard/Article/detail/503972?contextCategoryId=46496&ref=25 Calculating corneal spherical aberration—especially in eyes with extreme ranges of corneal spherical wavefront aberrations—by using the recorder function of a diagnostic system with analytical software may be beneficial when choosing an IOL that has positive, neutral, or negative SA to reduce postoperative SA in the whole eye. 2008-03-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/122008/503972null XML http://www.modernmedicine.com/modernmedicine/Cornea/SF6-associated-with-good-results-after-DSEK/ArticleStandard/Article/detail/504003?contextCategoryId=46496&ref=25 Sutureless Descemet's stripping with endothelial keratoplasty may be a reliable method of endothelial keratoplasty with the use of sulfur hexafluoride in place of filtered air. 2008-03-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/122008/504003null XML http://www.modernmedicine.com/modernmedicine/Cornea/Ocular-itching-drugs-are-numerous-in-the-pipeline/ArticleStandard/Article/detail/498980?contextCategoryId=46496&ref=25 To treat the ocular discomfort associated with allergic conjunctivitis several medications are in the pipeline. 2008-02-15T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/092008/498980null XML http://www.modernmedicine.com/modernmedicine/Cornea/Pivotal-trial-results-for-vernal-conjunctivitis-dr/ArticleStandard/Article/detail/498983?contextCategoryId=46496&ref=25 Results of a pivotal phase III trial of a cyclosporine A product for the treatment of vernal conjunctivitis (VKC) in children showed that the drug improved symptoms and signs of the orphan disease, and tolerability was excellent, according to the manufacturer. 2008-02-15T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/092008/498983null XML http://www.modernmedicine.com/modernmedicine/Cornea/Donor-endothelial-cell-counts-do-not-determine-dis/ArticleStandard/Article/detail/498988?contextCategoryId=46496&ref=25 Preoperative donor endothelial cell count does not affect the rate of dislocation in endothelial keratoplasty. The surgical technique is likely the most important factor that drives the dislocation rate, primary graft failure rate, and long-term endothelial survival, according to one surgeon. 2008-02-15T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/092008/498988null XML http://www.modernmedicine.com/modernmedicine/Cornea/Olopatadine-beneficial-for-perennial-allergic-conj/ArticleStandard/Article/detail/498982?contextCategoryId=46496&ref=25 A pooled analysis of three randomized, double-masked, placebo-controlled, conjunctival allergen challenge trials demonstrates that once-daily treatment with olopatadine 0.2% (Pataday, Alcon Laboratories) is equally effective for improving ocular itching caused by exposure to indoor or outdoor allergens. 2008-02-15T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/092008/498982null XML http://www.modernmedicine.com/modernmedicine/Cornea/Absence-of-drying-effect-makes-epinastine-a-treatm/ArticleStandard/Article/detail/498981?contextCategoryId=46496&ref=25 Epinastine HCl 0.05% does not have a drying effect on the ocular surface and may be kinder to patients being treated for seasonal allergies and underlying dry eye disease. 2008-02-15T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/092008/498981null XML http://www.modernmedicine.com/modernmedicine/Cornea/Study-evaluates-biological-integrity-of-corneal-ep/ArticleStandard/Article/detail/490637?contextCategoryId=46496&ref=25 The use of chilled water and 0.1% hyaluronic acid during epi-LASIK improved the survival rate of corneal epithelial basal cells, according to one study. 2008-02-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/072008/490637null XML http://www.modernmedicine.com/modernmedicine/Corneal+Disease/Cloudy-cornea/CustomizableHandout/Article/detail/551463?contextCategoryId=46496&ref=25 A cloudy cornea is a loss of transparency of the cornea. 2007-11-13T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/customizablehandout/modernmedicine/382008/551463null XML http://www.modernmedicine.com/modernmedicine/Corneal+Disease/Corneal-surgery/CustomizableHandout/Article/detail/553148?contextCategoryId=46496&ref=25 Corneal surgery corrects mild to moderate nearsightedness so you no longer need to wear glasses or contacts. 2007-02-22T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/customizablehandout/modernmedicine/392008/553148null XML http://www.modernmedicine.com/modernmedicine/Surgery/Corneal-Transplant/CustomizableHandout/Article/detail/551288?contextCategoryId=46496&ref=25 A corneal transplant is surgery to replace the clear surface on the front of the eye (the cornea). 2007-02-22T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/customizablehandout/modernmedicine/382008/551288null XML http://www.modernmedicine.com/modernmedicine/Corneal+Disease/Interstitial-keratitis/CustomizableHandout/Article/detail/545862?contextCategoryId=46496&ref=25 Interstitial keratitis is the inflammation of the connective tissue of the cornea (the clear window on the front of the eye), which can lead to vision loss. 2006-09-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/customizablehandout/modernmedicine/352008/545862null XML http://www.modernmedicine.com/modernmedicine/Corneal+Disease/Corneal-injury/CustomizableHandout/Article/detail/555096?contextCategoryId=46496&ref=25 Corneal injury describes an injury to the curved, transparent covering on the front of the eye. See also corneal ulcers and infections. 2006-08-08T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/customizablehandout/modernmedicine/402008/555096null XML http://www.modernmedicine.com/modernmedicine/Corneal+Disease/Corneal-ulcers-and-infections/CustomizableHandout/Article/detail/544405?contextCategoryId=46496&ref=25 The cornea is the transparent area at the front of the eyeball. A corneal ulcer is an erosion or open sore in the outer layer of the cornea. It is associated with infection by a bacterium, virus, fungus, or parasite. See also corneal injury. 2006-01-09T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/customizablehandout/modernmedicine/352008/544405null XML