http://www.modernmedicine.com/modernmedicine/Acne/Article/list/44678 Are you searching for a complete health care information resource? Modern Medicine provides vital information to doctors and other medical professionals. 2009-11-21T23:04:51Z http://www.modernmedicine.com/modernmedicine/Dermatology/Weight-based-dosing-Extended-release-minocycline-e/ArticleStandard/Article/detail/625932?contextCategoryId=44678&ref=25 Las Vegas — Weight-based dosing with extended-release (ER) minocycline tablets allows patients with acne to achieve efficacy equivalent to that of 2 mg/kg or 3 mg/kg of body weight daily with just 1 mg/kg daily, says James Q. Del Rosso, D.O., dermatology residency director, Valley Hospital Medical Center, Las Vegas. 2009-09-11T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/372009/625932null HTML http://www.modernmedicine.com/modernmedicine/E-newsletter/FDA-warns-Allergan-on-Aczone-promotion/ArticleStandard/Article/detail/623207?contextCategoryId=44678&ref=25 Washington — An advertisement for Aczone (Allergan), a gel used to treat mild-to-moderate acne, "grossly overstates" the drug’s effectiveness, the Food and Drug Administration (FDA) stated in a letter released Aug. 21. 2009-09-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/362009/623207null HTML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Getting-to-the-root-Look-below-the-surface-for-cau/ArticleStandard/Article/detail/616232?contextCategoryId=44678&ref=25 When female patients present with a combination of hair loss, hirsutism and acne, physicians should check total testosterone levels. 2009-08-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/322009/616232null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Gaining-control-Birth-control-pills-spironolactone/ArticleStandard/Article/detail/616248?contextCategoryId=44678&ref=25 Women can achieve good control of adult or hormonal acne through spironolactone therapy alone or in conjunction with oral contraceptives. 2009-08-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/322009/616248null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Exit-Accutane-Derms-reactions-mixed-as-Roche-pulls/ArticleStandard/Article/detail/616238?contextCategoryId=44678&ref=25 Dermatologists' reactions to Hoffman-La Roche's decision to discontinue its once-popular acne drug Accutane (isotretinoin) run the gamut. Some express disappointment or surprise; others marvel that the drug survived as long as it did. 2009-08-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/322009/616238null XML http://www.modernmedicine.com/modernmedicine/E-newsletter/Roche-stops-selling-Accutane-cant-compete-with-gen/ArticleStandard/Article/detail/608534?contextCategoryId=44678&ref=25 Zurich, Switzerland - Swiss drugmaker Roche Holding AG has decided to stop selling Accutane (isotretinoin), as it has reached the end of its life cycle and cannot compete with generic alternatives, Reuters reports. 2009-07-07T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/272009/608534null HTML http://www.modernmedicine.com/modernmedicine/Acne/BPO-gel-versus-wash-One-product-combination-has-qu/ArticleStandard/Article/detail/599872?contextCategoryId=44678&ref=25 A study comparing the safety and efficacy of two acne combination therapies containing clindamycin, benzoyl peroxide and tretinoin showed that the regimen delivered in gel vehicles worked faster than the regimen that included a benzoyl peroxide wash, the study's author says. 2009-06-02T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/222009/599872null HTML http://www.modernmedicine.com/modernmedicine/Acne/Smoke-and-mirrors-Study-shows-relationship-between/ArticleStandard/Article/detail/599853?contextCategoryId=44678&ref=25 Cigarette smokers are more likely to have severe acne when compared to non-smokers, according to the results of a recent study. Furthermore, abstinence from smoking may lead to significant improvements of acne lesions. 2009-06-02T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/222009/599853null HTML http://www.modernmedicine.com/modernmedicine/Acne/Blue-light-special-ALA-PDT-safe-effective-tool-for/ArticleStandard/Article/detail/599842?contextCategoryId=44678&ref=25 A recent study shows that ALA-PDT can be effective in the treatment of acne and particularly beneficial for inflammatory lesions. This treatment modality offers clinicians a safe and effective tool in treating acne lesions without the worries associated with long-term antibiotic therapy and isotretinoin therapy. 2009-06-02T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/222009/599842null HTML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Acne-treatments-New-options-tackle-clinical-compli/ArticleStandard/Article/detail/602139?contextCategoryId=44678&ref=25 Most of the significant recent advances in acne treatment involve changes in vehicle formulation that may improve medications' tolerability, efficacy or both, a leading clinician and researcher says. For treating tough acne cases, another expert adds, dermatologists must use simpler, more patient-friendly regimens. 2009-06-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/242009/602139null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Living-antibiotic-free-New-acne-fighting-combinati/ArticleStandard/Article/detail/602140?contextCategoryId=44678&ref=25 A newly approved acne medication that combines adapalene and benzoyl peroxide has shown safety and efficacy with daily use for up to one year and does not contribute to antibiotic resistance, a researcher says. 2009-06-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/242009/602140null XML http://www.modernmedicine.com/modernmedicine/E-newsletter/AARS-announces-Acne-Awareness-Month/ArticleStandard/Article/detail/600518?contextCategoryId=44678&ref=25 Hampton, N.H. ? The American Acne & Rosacea Society (AARS) has designated June 2009 as National Acne Awareness Month. The society hopes to educate healthcare providers about the treatment of acne through a series of live Webinars, according to a press release. 2009-06-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/222009/600518null HTML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/ALA-PDT-team-up-Combination-laser-therapy-proves-e/ArticleStandard/Article/detail/602138?contextCategoryId=44678&ref=25 A novel treatment approach using ALA-PDT in combination with standard topical therapies proves to be very effective in treating mild-to-severe acne lesions. According to one expert, this combination approach can achieve a high clearance of acne lesions and may be a solution for treating acne lesions long term. 2009-06-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/242009/602138null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Ganging-up-on-acne-Clindamycin-benzoyl-peroxide-co/ArticleStandard/Article/detail/602141?contextCategoryId=44678&ref=25 A gel combining benzoyl peroxide and clindamycin appears to reduce noninflammatory lesion counts more quickly than adapalene does for patients with mild to moderate acne, an expert says. 2009-06-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/242009/602141null XML http://www.modernmedicine.com/modernmedicine/E-newsletter/AARS-offers-CME-acne-Webinar/ArticleStandard/Article/detail/596676?contextCategoryId=44678&ref=25 National report ? The American Acne & Rosacea Society (AARS) is offering a CME Webinar for dermatologists nationwide this June in conjunction with the first annual National Acne Awareness Month, according to a Society press release. 2009-05-05T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/192009/596676null HTML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Whats-old-is-new-Topical-formulation-brings-dapson/ArticleStandard/Article/detail/596298?contextCategoryId=44678&ref=25 With oral dapsone plagued by concerns of hematological side effects, a topical formulation has given dapsone a safer, new role in treating some dermatologic conditions. 2009-05-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/182009/596298null XML http://www.modernmedicine.com/modernmedicine/Acne/Isotretinoin-and-suicide-Epidemiological-study-sho/ArticleStandard/Article/detail/595931?contextCategoryId=44678&ref=25 A new study involving cross-sectional samples of the U.S. population reveals no association between isotretinoin and suicidality, the study—s author says. 2009-04-30T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/182009/595931null HTML http://www.modernmedicine.com/modernmedicine/Acne/Antimicrobial-peptide-attacks-acne/ArticleStandard/Article/detail/595950?contextCategoryId=44678&ref=25 A new peptide has performed well in preclinical testing and could provide a potent antimicrobial punch against acne and, one day, methicillin-resistant Staphylococcus aureus, an expert says. 2009-04-30T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/182009/595950null HTML http://www.modernmedicine.com/modernmedicine/Acne/Tretinoin-gel-microsphere-less-irritating-than-ada/ArticleStandard/Article/detail/595953?contextCategoryId=44678&ref=25 Tretinoin gel microsphere 0.04 percent technology causes less facial skin irritation than does adapalene 0.3 percent, according to a recent study. 2009-04-30T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/182009/595953null HTML http://www.modernmedicine.com/modernmedicine/Psoriasis+Top+Story/Medical-advances-New-research-promises-novel-thera/ArticleStandard/Article/detail/592572?contextCategoryId=44678&ref=25 Advances in pediatric inflammatory skin diseases, such as psoriasis, acne and atopic dermatitis, have led to new therapies and better understanding of the underlying disease processes. 2009-04-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/152009/592572/84438806_flash.jpg XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/iPLEDGE-update-Program-has-improved-reporting-of-p/ArticleStandard/Article/detail/592558?contextCategoryId=44678&ref=25 As iPLEDGE begins its fourth year, dermatologists say they and their patients have accepted it despite occasional problems. 2009-04-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/152009/592558null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Population-control-New-combination-treatments-redu/ArticleStandard/Article/detail/585620?contextCategoryId=44678&ref=25 Combination treatment for acne continues to evolve, helping doctors address the sometimes tough-to-tackle condition. 2009-03-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/102009/585620null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Bumpy-Boy/ArticleStandard/Article/detail/587079?contextCategoryId=44678&ref=25 A 4-year-old is brought in to doctor's office due to monomorphous bumps that appeared two months earlier 2009-03-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/contpeds/112009/587079null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/New-help-for-acne-Large-study-shows-new-combinatio/ArticleStandard/Article/detail/585618?contextCategoryId=44678&ref=25 A single product that combines a retinoid and benzoyl peroxide is showing promise against acne. The new gel is not only safe and effective, but fast-acting, too. 2009-03-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/102009/585618null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/An-unwelcome-eruption-periorificial-dermatitis/ArticleStandard/Article/detail/581804?contextCategoryId=44678&ref=25 An 11-year-old comes into the office with an asymptomatic slowly progressive eruption that began 3 years prior. The problem is finally resolved with topical and/or systemic treatment. 2009-02-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/contpeds/082009/581804null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Anti-acne-peel-Innovative-topical-therapy-effectiv/ArticleStandard/Article/detail/578201?contextCategoryId=44678&ref=25 A novel peel is proving to be very effective in the treatment of comedonic as well as mild-to-moderate acne lesions. This approach could spare acne patients from repeated antibiotic therapies for considerably benign cosmetic lesions. 2009-02-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/052009/578201null XML http://dermatologytimes.modernmedicine.com/dermatologytimes/Modern+Medicine+Conference+News/Conference-News-Acne-armamentarium/ArticleStandard/Article/detail/576221?contextCategoryId=44678&ref=25 Kohala Coast, HI — Recent approvals are further expanding the armamentarium of topical agents for the treatment of acne, as well as providing practitioners with the advantages of having more options to choose from in managing this common dermatologic disease, said James Q. Del Rosso, D.O., at the Winter Clinical Dermatology Conference. 2009-01-19T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/042009/576221null HTML http://dermatologytimes.modernmedicine.com/dermatologytimes/Modern+Medicine+Conference+News/Conference-News-Systemic-therapy-for-acne/ArticleStandard/Article/detail/576009?contextCategoryId=44678&ref=25 Kohala Coast, HI — Newer oral antibiotics have a reduced side-effect profile and increased efficacy in the treatment of acne, said Hilary Baldwin, M.D., at the Winter Clinical Dermatology Conference. 2009-01-18T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/042009/576009null HTML http://dermatologytimes.modernmedicine.com/dermatologytimes/E-newsletter/Conference-News-Topical-therapy-update/ArticleStandard/Article/detail/575998?contextCategoryId=44678&ref=25 Kohala Coast, HI — Topical therapy continues to be a mainstay in dermatologic therapy, and innovative products and therapeutic approaches are needed because compliance with traditional topical regimens is poor, said Alan B. Fleischer, Jr, MD, at this year's Winter Clinical Dermatology Conference. 2009-01-17T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/032009/575998null HTML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Rosacea-Lasers-lights-play-role-in-treatment-of-so/ArticleStandard/Article/detail/573436?contextCategoryId=44678&ref=25 Rosacea is a common skin disorder that affects 14 million Americans. Though the condition is sometimes mild in nature, many patients with rosacea have lower self-esteem and tend to avoid public contact or cancel social engagements. 2009-01-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/012008/573436null XML http://www.modernmedicine.com/modernmedicine/E-newsletter/Acne-cream-recalled-from-Wal-Mart-Kroger-Dollar-Ge/ArticleStandard/Article/detail/568504?contextCategoryId=44678&ref=25 National report ? CSI, USA has issued a recall for all 1 ounce tubes of 10 percent benzoyl peroxide acne cream, which were sold under different names at Kroger, Wal-Mart and Dollar General, due to possible contamination with Burkholderia Cepacia bacteria, AboutLawsuits.com reports. 2008-12-02T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/482008/568504null HTML http://www.modernmedicine.com/modernmedicine/E-newsletter/FDA-approves-Acanya-Gel-for-the-treatment-of-acne/ArticleStandard/Article/detail/568502?contextCategoryId=44678&ref=25 Redwood City, Calif. ? Arcutis Pharmaceuticals announces the Food and Drug Administration (FDA) approval of Acanya Gel (clindamycin phosphate 1.2 percent and benzoyl peroxide 2.5 percent) for the once-daily treatment of acne vulgaris in patients 12 years and older, according to BusinessWire. 2008-12-02T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/482008/568502null HTML http://www.modernmedicine.com/modernmedicine/Laser+%26+Light+Technology+in+Dermatology+Top+Story/Light-intensifier-LED-combo-treats-rosacea-erythem/ArticleStandard/Article/detail/570108?contextCategoryId=44678&ref=25 Combining LED therapy with laser or intense pulsed light can effectively treat rosacea and subsequent erythema, an expert says. 2008-12-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/492008/570108null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Delving-deeper-Rosacea-peptide-research-focuses-on/ArticleStandard/Article/detail/563252?contextCategoryId=44678&ref=25 Cathelicidins appear to have dual roles in the skin, working not just as antimicrobials that act as natural antibiotics but also as proponents of healing. Researchers are looking into the underlying workings of antimicrobial cathelicidins with the hope of better understanding their role in osacea. Factors such as toll-like receptors and vitamin D3 appear to be part of the equation. 2008-11-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/452008/563252null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Special-considerations-Exacerbating-factors-mandat/ArticleStandard/Article/detail/562925?contextCategoryId=44678&ref=25 Topical retinoid treatment is the mainstay of acne management in ethnic skin, as it is in fairer individuals. However, additional considerations are needed to address the unique postinflammatory sequelæ in dark skin and precipitating factors for acne eruptions. 2008-11-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/452008/562925null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Off-site-rosacea-Presentation-on-scalp-back-chest-/ArticleStandard/Article/detail/563253?contextCategoryId=44678&ref=25 A classic 1-2-3 approach to treating rosacea of the body and scalp is effective, an expert says. 2008-11-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/452008/563253null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/3-D-technology-State-of-the-art-imaging-system-inc/ArticleStandard/Article/detail/562922?contextCategoryId=44678&ref=25 The state-of-the-art 3-D imaging system known as Lifeviz raises the bar in the management of acne and rosacea lesions by allowing the clinician to visualize much more accurately lesion images and, therefore, better follow the treatment progress of patients. 2008-11-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/452008/562922null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Photodynamic-therapy-MAL-PDT-improves-inflammatory/ArticleStandard/Article/detail/562921?contextCategoryId=44678&ref=25 Photodynamic therapy with methyl aminolevulinate cream and red light is associated with marked and relatively durable reductions in inflammatory lesion counts in patients with moderate inflammatory acne, an expert says. 2008-11-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/452008/562921/male_acne_flash.jpg XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Natural-niche-Cosmeceuticals-play-role-in-rosacea-/ArticleStandard/Article/detail/563250?contextCategoryId=44678&ref=25 Cosmeceuticals such as Kinerase (Valeant), niacinamide and a combination of methylsulfonylmethane and silymarin can have a place in treating rosacea, particularly when there is a reason why pharmacological therapies can be used. However, as the number of treatments claiming to help with skin redness grows, physicians shouldwarn patients that just because something can treat redness, that doesn't necessarily mean it can treat rosacea. 2008-11-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/452008/563250null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Synergistic-effect-Combining-LED-devices-with-PDL-/ArticleStandard/Article/detail/563248?contextCategoryId=44678&ref=25 Combining laser and light-based treatments for rosacea have a synergistic effect, and the combination works better than each does separately, an expert says. 2008-11-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/452008/563248null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Now-on-trial-New-rosacea-medications-hold-promise-/ArticleStandard/Article/detail/563251?contextCategoryId=44678&ref=25 Several new compounds are currently being tested for safety and efficacy in treating rosacea. These medications may make treatment easier for patients, an expert says. 2008-11-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/452008/563251null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Study-Minocycline-associated-with-autoimmunity/ArticleStandard/Article/detail/564369?contextCategoryId=44678&ref=25 Minocycline may induce potentially serious autoimmune phenomena in children with acne. 2008-11-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/contpeds/452008/564369null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Acne-pathogenesis-Researchers-focus-on-elucidating/ArticleStandard/Article/detail/562923?contextCategoryId=44678&ref=25 Tissue necrosis factor-alpha (TNF-alpha) is a pivotal cytokine in inflammatory pathways, but its role in acne has not been characterized. Studies under way at the University of Miami Miller School of Medicine aim to elucidate more information with the ultimate goal of identifying potential new therapeutic targets for acne. 2008-11-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/452008/562923null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Skin-of-color-Studies-lacking-on-rosacea-in-ethnic/ArticleStandard/Article/detail/563249?contextCategoryId=44678&ref=25 Although there is a lot of ongoing research into rosacea and a number of FDA-approved medications, very little of either have to do with skin of color. Research protocols have not included ethnic skin, and medications were approved before the FDA required the inclusion of ethnic subjects. 2008-11-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/452008/563249/DT11803rosaceaBLACKEYES_rev_flash.jpg XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Photopneumatic-therapy-Vacuum-assisted-pulsed-ligh/ArticleStandard/Article/detail/562920?contextCategoryId=44678&ref=25 Patients with acne that is unresponsive to traditional therapies were enrolled in a multicenter study evaluating photopneumatic therapy with a vacuum-assisted pulsed light device (Isolaz, æsthera). The treatment was easy to deliver and well-tolerated. 2008-11-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/452008/562920null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/New-developments-in-acne-treatment-Novel-topical-o/ArticleStandard/Article/detail/562924?contextCategoryId=44678&ref=25 Dapsone gel, Oracea capsules and modified photodynamic therapy are three brand-new approaches to acne therapy, all of which may change current acne treatment and management. 2008-11-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/452008/562924null XML http://www.modernmedicine.com/modernmedicine/Acne/Making-the-grade-New-acne-severity-index-helps-doc/ArticleStandard/Article/detail/556561?contextCategoryId=44678&ref=25 The new Bikowski Acne Severity Index (BASI) effectively combines common medical jargon for describing acne lesions, which helps physicians grade these lesions more accurately. 2008-10-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/412008/556561null XML http://www.modernmedicine.com/modernmedicine/Acne/iPLEDGE-compliance-Program-protects-patient-prescr/ArticleStandard/Article/detail/547625?contextCategoryId=44678&ref=25 The iPLEDGE program is excellent for protecting the prescriber, so that he or she can continue to practice medicine and responsibly care for patients with severe acne, one dermatologist says. However, the issue of compliance remains a major hurdle. 2008-09-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/362008/547625null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Steroid-Doping-Can-Cause-Severe-Acne-Conglobata/ArticleNewsFeed/Article/detail/543865?contextCategoryId=44678&ref=25 Doping with anabolic steroids -- a common practice in professional and amateur sports -- can cause severe skin lesions that result in permanent scarring, according to an article published in the Aug. 23 issue of The Lancet. 2008-08-22T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/312009/543865/109081.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/312009/543865null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Adolescents-Prefer-Total-Acne-Clearance-Strategy/ArticleNewsFeed/Article/detail/543306?contextCategoryId=44678&ref=25 Adolescent acne patients prefer a treatment strategy that would offer 100 percent acne clearance without scarring, and would be willing to pay more money to achieve this outcome, according to a study published in the August issue of the Archives of Dermatology. 2008-08-19T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/342008/543306/teengirls.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/342008/543306null XML http://www.modernmedicine.com/modernmedicine/Acne/Taking-the-red-out-of-rosacea-Topical-alpha-1-adre/ArticleStandard/Article/detail/535065?contextCategoryId=44678&ref=25 Topical treatment with a 0.05 percent solution of oxymetazoline in a small series of patients with erythematotelangiectatic rosacea has been associated with encouraging efficacy for reducing erythema and preventing erythematous flares. Aspect Pharmaceuticals is planning a clinical trial of a formula optimized for dermatologic use. 2008-08-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/332008/535065null XML http://www.modernmedicine.com/modernmedicine/Special+Report%3A+Athletes+%26+Skin+Disease/Athletes-and-acne-mechanica-Look-to-nonporous-mate/ArticleStandard/Article/detail/535072?contextCategoryId=44678&ref=25 Physicians who work with teens, athletes or even musicians are likely to encounter acne mechanica. Characterized by small red bumps, acne mechanica typically occurs when nonporous material, such as a strap or helmet, is in regular contact with the skin. 2008-08-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/332008/535072null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/New-Laser-Technique-May-Reduce-Acne-Scars/ArticleNewsFeed/Article/detail/531732?contextCategoryId=44678&ref=25 In patients with acne scars, ablative fractional resurfacing with a novel 30-watt laser that combines carbon dioxide ablation with a fractional photothermolysis system may significantly improve facial appearance with minimal side effects, according to study findings published in the August issue of Lasers in Surgery and Medicine. 2008-07-24T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/302008/531732/Fac075ml.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/302008/531732null XML http://www.modernmedicine.com/modernmedicine/E-newsletter/NRS-survey-suggests-links-between-rosacea-and-gene/ArticleStandard/Article/detail/526025?contextCategoryId=44678&ref=25 Barrington, Ill. — Results of a recently released survey indicate that rosacea may be genetic, the National Rosacea Society (NRS) reports. 2008-07-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/262008/526025null HTML http://www.modernmedicine.com/modernmedicine/E-newsletter/Obagi-reports-positive-results-in-testing-of-acne-/ArticleStandard/Article/detail/526027?contextCategoryId=44678&ref=25 Long Beach, Calif. — Obagi Medical Products, based here, has released results of a study on its solubilized 5 percent benzoyl peroxide (BPO) gel treatment for acne, Business Wire reports. 2008-07-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/262008/526027null HTML http://www.modernmedicine.com/modernmedicine/E-newsletter/Isotretinoin-use-increases-risk-of-depression-stud/ArticleStandard/Article/detail/520217?contextCategoryId=44678&ref=25 Montreal — Isotretinoin, the active ingredient in the acne drug Accutane (Roche Laboratories), could more than double the risk of depression, according to results of a study reported by Reuters Health. 2008-06-03T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/222008/520217null HTML http://www.modernmedicine.com/modernmedicine/Editorial/Commentary-Dealing-with-teen-patients-that-are-plu/ArticleStandard/Article/detail/521325?contextCategoryId=44678&ref=25 Have you ever met anybody who is plugged in and tuned out? How about the acne patient who is listening to an ipod when you enter the room and continues to listen despite your greeting? How about the acne patient and their parent who are both listening to their own separate ipods and continuing to listen despite your greeting? What should you do? 2008-06-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/232008/521325null XML http://www.modernmedicine.com/modernmedicine/Special+Report%3A+Pigmentary+Problems/Hyperpigmentation-and-skin-disease-Problem-exacerb/ArticleStandard/Article/detail/521341?contextCategoryId=44678&ref=25 Acne, eczema, psoriasis, are all skin conditions that can cause discomfort and embarrassment. But for many patients, the worst part of these and a number of other skin ailments may be the residual pigmentation left behind even when the conditions are successfully treated. 2008-06-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/232008/521341null XML http://www.modernmedicine.com/modernmedicine/News/Drug-safety-Isotretinoin-makers-to-comply-with-new/ArticleStandard/Article/detail/515828?contextCategoryId=44678&ref=25 Manufacturers of isotretinoin are awaiting more information to determine whether iPLEDGE — the mandatory federal drug registry already in place — will meet the Food and Drug Administration's new safety plan requirements. 2008-05-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/192008/515828null XML http://www.modernmedicine.com/modernmedicine/News/Decoding-isotretinoin-Understanding-mechanism-of-a/ArticleStandard/Article/detail/515835?contextCategoryId=44678&ref=25 Isotretinoin is a potent therapy for treating acne, but the associated side effects and regulatory hurdles leave dermatologists increasingly reluctant to use it. 2008-05-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/192008/515835null XML http://www.modernmedicine.com/modernmedicine/Acne/Oral-Contraceptive-Use-May-Increase-in-Acne-Treatm/ArticleNewsFeed/Article/detail/512212?contextCategoryId=44678&ref=25 Recently changed guideline stating that physicians no longer need to perform a pelvic examination and Papanicolaou smear before prescribing oral contraceptive pills may encourage more dermatologists to prescribe the pills as an acne treatment for women of childbearing age, according to an article published in the May issue of the Journal of the American Academy of Dermatology. 2008-04-24T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/172008/512212/59256.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/172008/512212null XML http://www.modernmedicine.com/modernmedicine/Acne/Skim-Milk-Linked-to-Acne-in-Teenage-Boys/ArticleNewsFeed/Article/detail/511849?contextCategoryId=44678&ref=25 In teenage boys, high consumption of skim milk is positively associated with acne, according to a study published in the May issue of the Journal of the American Academy of Dermatology. 2008-04-23T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/172008/511849/67091.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/172008/511849null XML http://www.modernmedicine.com/modernmedicine/Dermatology/Acne/CustomizableHandout/Article/detail/554935?contextCategoryId=44678&ref=25 Acne is a skin condition characterized by whiteheads, blackheads, and inflamed red pimples or "zits." 2008-04-14T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/customizablehandout/modernmedicine/402008/554935null XML http://www.modernmedicine.com/modernmedicine/Research+Briefs/FDA-gives-Portrait-R-Plasma-clearance-to-treat-acn/ArticleStandard/Article/detail/507440?contextCategoryId=44678&ref=25 Waltham, Mass. — The Food and Drug Administration (FDA) has approved the Portrait (R) Plasma (Rhytec) for the treatments of acne scars, PRNewswire reports. 2008-04-03T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/142008/507440null HTML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/New-Photopneumatic-Therapy-to-Treat-Acne/ArticleNewsFeed/Article/detail/499995?contextCategoryId=44678&ref=25 A novel device using a vacuum and a broadband light source can safely and effectively treat mild to severe acne vulgaris, according to a report published in the February issue of the Journal of Drugs in Dermatology. 2008-03-03T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/362009/499995/46100.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/362009/499995null XML http://www.modernmedicine.com/modernmedicine/Acne/New-acne-drug-formulation-offers-improved-tolerabi/ArticleStandard/Article/detail/500774?contextCategoryId=44678&ref=25 A new acne drug, Atralin, works comparably to tretinoin alternatives, but offers better tolerability due to formulation including hyaluronic acid, collagen and glycerin, according to a 12-week, multi-site, blinded, randomized study. 2008-03-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/102008/500774null XML http://www.modernmedicine.com/modernmedicine/Dermatology/Adolescent-Acne-Education-Materials-Compared/ArticleNewsFeed/Article/detail/492640?contextCategoryId=44678&ref=25 Printed educational materials and brief audiovisual presentations are both effective in increasing adolescents' knowledge about acne, researchers report in the February issue of the Archives of Dermatology. 2008-02-19T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/082008/492640/teen_girl.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/082008/492640null XML http://www.modernmedicine.com/modernmedicine/Acne/Rosacea/CustomizableHandout/Article/detail/554941?contextCategoryId=44678&ref=25 Rosacea is a chronic skin condition involving inflammation of the cheeks, nose, chin, forehead, or eyelids. It may appear as redness, prominent spider-like blood vessels, swelling, or skin eruptions similar to acne. 2008-02-05T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/customizablehandout/modernmedicine/402008/554941null XML http://www.modernmedicine.com/modernmedicine/Acne/Combination-product-offers-stability-flexibility-i/ArticleStandard/Article/detail/492799?contextCategoryId=44678&ref=25 Results from a series of in vitro studies show a new combination clindamycin/tretinoin product (Zianis, Medicis) may potentially be applied sequentially with benzoyl peroxide without concern about loss of activity from tretinoin degradation. 2008-02-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/082008/492799null XML http://www.modernmedicine.com/modernmedicine/Acne/Maximizing-acne-treatment/ArticleStandard/Article/detail/492808?contextCategoryId=44678&ref=25 Effective combination therapy for acne requires addressing all four of this condition's causes while avoiding bothersome side effects and minimizing antibiotic resistance, according to an expert. 2008-02-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/082008/492808null XML http://www.modernmedicine.com/modernmedicine/Adolescent+Medicine/Contemporary-acne-treatment-options-Achieving-opti/ArticleStandard/Article/detail/448723?contextCategoryId=44678&ref=25 Acne affects almost all adolescents and adults at some point in their lives but is highly treatable with topical retinoids and antibacterials. The type and severity of acne guide early intervention, which can prevent disfigurement and its psychosocial sequelæ. 2007-08-18T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/patcare/322007/448723null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Milia/ArticleStandard/Article/detail/539317?contextCategoryId=44678&ref=25 2007-04-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/332008/539317null XML http://www.modernmedicine.com/modernmedicine/Acne/Teenagers-and-acne-medicine/CustomizableHandout/Article/detail/545973?contextCategoryId=44678&ref=25 Acne and teenagers 2006-12-18T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/customizablehandout/modernmedicine/352008/545973null XML http://www.modernmedicine.com/modernmedicine/Acne/Acne-trials-explore-variety-of-treatment-safety-ef/ArticleStandard/Article/detail/383311?contextCategoryId=44678&ref=25 The topical retinoid was significantly superior to vehicle control for maintaining disease improvement. 2006-11-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/442006/383311null XML http://www.modernmedicine.com/modernmedicine/Acne/PDT-effective-for-acne/ArticleStandard/Article/detail/383313?contextCategoryId=44678&ref=25 As heightened regulations put greater limitations than ever on prescribing isotretinoin, photodynamic light therapy is gaining more attention as an effective alternative for acne treatment, says Arielle Kauvar, M.D., associate director at the Laser and Skin Surgery Center of New York, and clinical associate professor of dermatology, New York University School of Medicine, New York. 2006-11-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/442006/383313null XML http://www.modernmedicine.com/modernmedicine/isotretinoin/Isotretinoin-possibly-linked-to-IBD/ArticleStandard/Article/detail/375418?contextCategoryId=44678&ref=25 The first systematic review of inflammatory bowel disease (IBD) in isotretinoin users shows that this drug may trigger IBD in certain patients. While the Physician's Desk Reference lists IBD as a possible adverse event associated with use of isotretinoin, "Our goal was primarily to determine if this association was legitimate," and if so, what it means to physicians and patients, Corey A. Siegel, M.D., says. He is one of the review's authors and assistant professor of medicine and director of the Dartmouth-Hitchcock Inflammatory Bowel Disease Center in Lebanon, N.H. 2006-10-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/392006/375418null XML http://www.modernmedicine.com/modernmedicine/Cosmetic+Dermatology/Lasers-for-acne-Not-a-match-made-in-heaven-mdash-y/ArticleStandard/Article/detail/375443?contextCategoryId=44678&ref=25 Scottsdale, Ariz. — Lasers and light-based therapies are evolving with increasingly promising results for treatment of acne, but their place is still decidedly only as an adjunct therapy, according to doctors debating the topic at a recent meeting of the Skin Disease Education Foundation. 2006-10-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/392006/375443null XML http://www.modernmedicine.com/modernmedicine/Clinical+News/Isotretinoin-may-trigger-IBD-in-subgroup-of-patien/ArticleStandard/Article/detail/381304?contextCategoryId=44678&ref=25 A review of adverse event data associated with the synthetic vitamin A retinoid isotretinoin between 1997 and 2002 suggests that the acne treatment is a "probable" cause of inflammatory bowel disease (IBD) and may precipitate its presentation within a certain subset of patients who are either predisposed to the disease or have subclinical symptoms. 2006-10-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/formulary/432006/381304null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Pediatric-Chest-Pain-Keys-to-the-Diagnosis/ArticleStandard/Article/detail/537750?contextCategoryId=44678&ref=25 Chest pain in children evokes anxiety in patients and their parents--and prompts frequent visits to the pediatrician's office, urgent care facility, or emergency department (ED). In a prospective study, Selbst and colleagues reported that chest pain accounted for 6 in 1000 visits to an urban pediatric ED. 2006-08-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/332008/537750null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Photoclinic-Neonatal-Acne/ArticleStandard/Article/detail/537349?contextCategoryId=44678&ref=25 The parents of a 3-week-old infant are concerned about the numerous small, erythematous papules and pustules on his cheeks. All the lesions were at a similar stage in development. The pregnancy was uneventful. 2006-04-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/332008/537349null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Can-You-Identify-The-Disorders-Pictured-Here/ArticleStandard/Article/detail/537228?contextCategoryId=44678&ref=25 A pruritic facial eruption; asymptomatic, erythematous lesions; a persistent papule--can you identify the disorders pictured here? 2006-02-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/332008/537228null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Refractory-Acne-Vulgaris/ArticleStandard/Article/detail/536900?contextCategoryId=44678&ref=25 For the past 3 years, comedones, papules, pustules, and nodules had been erupting on the face of a 16-year-old boy. 2005-09-14T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/332008/536900null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Steroid-Acne/ArticleStandard/Article/detail/536416?contextCategoryId=44678&ref=25 Five days after beginning aggressive treatment with intravenous corticosteroids for inflammatory bowel disease, this 26-year-old man noticed the sudden eruption of this mildly pruritic rash. 2005-09-14T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/332008/536416null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Acne-Estivalis/ArticleStandard/Article/detail/536960?contextCategoryId=44678&ref=25 The lesions seen here developed shortly after a 54-year-old woman started psoralen plus UVA (PUVA) therapy for psoriasis 2005-09-14T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/332008/536960null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Keloid/ArticleStandard/Article/detail/536389?contextCategoryId=44678&ref=25 During the last 3 months, scars had developed on the sternal area of a 25-year-old black woman. 2005-09-14T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/332008/536389null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Hidradenitis-Suppurativa/ArticleStandard/Article/detail/536051?contextCategoryId=44678&ref=25 Painful cysts on the sternal and left axillary regions that had worsened over the past 3 weeks prompted a 42-year-old man to seek medical care. He reported that similar lesions in the same distribution first arose when he was 25 years old, 2005-03-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/332008/536051null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/A-Photo-Quiz-to-Hone-Dermatologic-Skills/ArticleStandard/Article/detail/535792?contextCategoryId=44678&ref=25 A slightly pruritic, red, scaly rash on an 8-year-old boy’s hands has been progressively worsening since it appeared 4 months earlier. Nail pitting also was noted. There are no other rashes on his body. The patient is active in sports; denies any new exposure to soaps, clothing, or other contactants; and spends time in the homes of his recently divorced parents. 2003-08-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/332008/535792null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Lymphangioma-Circumscriptum/ArticleStandard/Article/detail/535770?contextCategoryId=44678&ref=25 For 10 years, a 22-year-old woman had had an erythematous, translucent patch of grouped blisters on her left thigh. A recent increase in the size of the patch prompted the patient to seek treatment. 2003-01-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/332008/535770null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/A-Photo-Quiz-to-Hone-Dermatologic-Skills/ArticleStandard/Article/detail/535592?contextCategoryId=44678&ref=25 A 37-year-old woman complains of “itchy bumps” that erupted just above her waist 2 or 3 days earlier. She denies having had this condition in the past. The patient is otherwise healthy and takes no medications. An avid gardener, she claims to be able to identify and avoid poisonous plants. 2002-09-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/332008/535592null XML http://www.modernmedicine.com/modernmedicine/Endocrinology/Refractory-Acne-Vulgaris/ArticleStandard/Article/detail/535652?contextCategoryId=44678&ref=25 For the past 3 years, comedones, papules, pustules, and nodules had been erupting on the face of a 16-year-old boy. Acne vulgaris had been diagnosed. Topical tetracycline cream and oral tetracycline were used without success. 2002-03-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/332008/535652null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Tinea-Versicolor-Case-6/ArticleStandard/Article/detail/535431?contextCategoryId=44678&ref=25 A 16-year-old black girl complained of a gradually worsening facial eruption. She had been assured by her family physician that this was caused by an allergy to soap; she applied over-the-counter 1% hydrocortisone cream daily. 1999-10-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/332008/535431null XML