http://www.modernmedicine.com/modernmedicine/Epilepsy/Article/list/41815 The Epilepsy Condition Center is a section on Modern Medicine that provides news, clinical articles and CME activities about epilepsy. Clinical articles cover diagnosis and seizure control using anti-epileptic drugs (AED). Epileptic seizures result from electrical hypersynchronization of neuronal networks in the cerebral cortex. Epilepsy is characterized by recurrent epileptic seizures due to a genetically determined or acquired brain disorder. Visit this section and learn more about current medical information about epilepsy and anti-convulsive drugs. 2009-11-21T20:52:16Z http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Smoking-Linked-to-Higher-Seizure-Risk-in-Women/ArticleNewsFeed/Article/detail/642974?contextCategoryId=41815&ref=25 Women who smoke have a higher risk of seizure, while past smokers have a modestly increased risk of epilepsy, according to a study published in Epilepsia. 2009-11-19T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/472009/642974/SS42028.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/472009/642974null XML http://www.modernmedicine.com/modernmedicine/CME+Showcase/Hot-Topics-In-Neuropathic-Pain-Progress-and-Possib/CME/Article/detail/639280?contextCategoryId=41815&ref=25 In the United States, 2% to 3% of the population is affected by neuropathic pain, with postherpetic neuralgia and diabetic peripheral neuropathic pain being the most common. Symptoms include allodynia, paresthesia, and hyperalgesia, as well as partial or complete loss of sensation and muscle weakness. The impact of neuropathic pain on a patient's quality of life is overwhelmingly negative. 2009-11-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/cme/modernmedicine/452009/639280null REMOTE http://www.modernmedicine.com/modernmedicine/Endocrinology/Study-Evaluates-Hospital-Quality-and-Mortality-Rat/ArticleNewsFeed/Article/detail/633747?contextCategoryId=41815&ref=25 Hospital mortality rates in the United States have improved, although major differences in quality still exist between the best and worst hospitals, according to a report published Oct. 13 by HealthGrades. 2009-10-13T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/422009/633747/hospitalsign_18169.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/422009/633747null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/New-Microcephaly-Evaluation-Guidelines-Issued/ArticleNewsFeed/Article/detail/626619?contextCategoryId=41815&ref=25 Because microcephaly is associated with developmental delays, learning disorders and neurologic conditions, children with microcephaly should be screened for such problems, according to a special article published in the Sept. 15 issue of Neurology. 2009-09-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/382009/626619/SS36032.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/382009/626619null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Antipyretics-Not-Found-to-Stop-Recurrent-Febrile-S/ArticleNewsFeed/Article/detail/625105?contextCategoryId=41815&ref=25 Antipyretic agents cannot prevent the recurrence of febrile seizures, although they can lower temperature in non-seizure febrile episodes, according to a study in the September issue of the Archives of Pediatrics & Adolescent Medicine. 2009-09-09T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/372009/625105/thermometer_59113.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/372009/625105null XML http://www.modernmedicine.com/modernmedicine/Medical+Economics+CME/First-seizures/CME/Article/detail/619888?contextCategoryId=41815&ref=25 2009-08-21T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/cme/memag/342009/619888null REMOTE http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Seizures-Uncommon-in-Alzheimers-Disease-Patients/ArticleNewsFeed/Article/detail/620717?contextCategoryId=41815&ref=25 Seizures appear uncommon in patients with Alzheimer's disease, but they may be more likely to occur in younger patients, according to research published in the August issue of the Archives of Neurology. 2009-08-20T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/342009/620717/BRAIN.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/342009/620717null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/First-Epileptic-Seizure-Linked-to-Cognitive-Defici/ArticleNewsFeed/Article/detail/618956?contextCategoryId=41815&ref=25 Intellectually normal children with a first recognized epileptic seizure are significantly more likely than their healthy siblings to exhibit neuropsychological deficits, which suggests there is a window of opportunity for treatment that could reduce subsequent effects on academic performance, according to a study published online Aug. 12 in Neurology. 2009-08-13T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/332009/618956/brainepilepsy.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/332009/618956null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Uncontrolled-Seizures-Impact-Pregnancy-Outcomes/ArticleNewsFeed/Article/detail/618534?contextCategoryId=41815&ref=25 Seizure prevention is essential for pregnant women with epilepsy to reduce adverse outcomes associated with uncontrolled disease, according to a study published in the August issue of the Archives of Neurology. 2009-08-12T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/332009/618534/40279.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/332009/618534null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Potassium-Citrate-May-Prevent-Stones-in-Ketogenic-/ArticleNewsFeed/Article/detail/610738?contextCategoryId=41815&ref=25 An oral potassium citrate supplement, Polycitra K, can prevent the formation of kidney stones in children put on a ketogenic diet for intractable epilepsy, according to a study published online July 13 in Pediatrics. 2009-07-13T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/292009/610738/15339.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/292009/610738null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Continuous-EEG-Spots-Hidden-Brain-Injury-in-Critic/ArticleNewsFeed/Article/detail/605193?contextCategoryId=41815&ref=25 Continuous electroencephalography may help to identify patients with otherwise undetectable seizures, according to a study published in the June issue of Critical Care Medicine, while a study published online April 13 in the Annals of Neurology found that intracortical EEG is better than scalp EEG for detection of secondary neuronal injury. 2009-06-19T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/312009/605193/BRAINsmall.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/312009/605193null XML http://www.modernmedicine.com/modernmedicine/Pathology/Mouse-Model-Sheds-Light-on-iARXi-Infantile-Spasms/ArticleNewsFeed/Article/detail/604208?contextCategoryId=41815&ref=25 A mouse model of pediatric epilepsy with features of infantile spasms, along with new findings in families with gene mutations linked to infantile spasms, could change the counseling given to families of children with such mutations, according to research published in the June issue of Brain. 2009-06-16T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/252009/604208/mouse.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/252009/604208null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/AAN-Pregnancy-Is-Usually-Safe-for-Epileptics/ArticleNewsFeed/Article/detail/595327?contextCategoryId=41815&ref=25 Female epileptics of childbearing age can expect good pregnancy outcomes if they avoid valproate during pregnancy and take other precautions, according to new guidelines presented at the 61st annual meeting of the American Academy of Neurology held April 25 to May 2 in Seattle and published online April 27 in Neurology. 2009-04-28T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/182009/595327/46131.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/182009/595327null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Valproate-in-Pregnancy-Linked-to-Lower-IQ-in-Child/ArticleNewsFeed/Article/detail/593637?contextCategoryId=41815&ref=25 The use of valproate in pregnant women with epilepsy is associated with a higher risk of impaired cognitive function in their children at the age of 3, according to research published in the April 16 issue of the New England Journal of Medicine. 2009-04-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/162009/593637/10049.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/162009/593637null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Benefits-Seen-From-Early-Epilepsy-Surgery/ArticleNewsFeed/Article/detail/591445?contextCategoryId=41815&ref=25 Surgery to treat epilepsy in young children appears generally safe and effective, according to research published online ahead of print Jan. 21 in Epilepsia. 2009-04-03T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/142009/591445/brainepilepsy.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/142009/591445null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Switching-Anticonvulsant-Drugs-Cuts-Cardiovascular/ArticleNewsFeed/Article/detail/589054?contextCategoryId=41815&ref=25 Switching to anticonvulsant drugs that don't activate cytochrome P450 enzymes can improve blood cholesterol levels and lower cardiovascular risk in epilepsy patients, according to research published online March 18 in the Annals of Neurology. 2009-03-24T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/132009/589054/prescription_18142.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/132009/589054null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Long-Term-Epilepsy-Risk-High-After-Traumatic-Brain/ArticleNewsFeed/Article/detail/583033?contextCategoryId=41815&ref=25 In children and young adults with traumatic brain injury, the risk of epilepsy persists for 10 years or longer, according to a report published online Feb. 23 in The Lancet. 2009-02-23T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092009/583033/skullxray_SS36090.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092009/583033null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Brain-Surgery-Shows-Benefit-in-Pediatric-Stroke-Pa/ArticleNewsFeed/Article/detail/582950?contextCategoryId=41815&ref=25 Periinsular hemispherotomy may be useful in treating stroke-induced refractory epilepsy in children, according to research published in the February issue of the Journal of Neurosurgery: Pediatrics. 2009-02-23T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092009/582950/brainepilepsy.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092009/582950null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Better-Visual-Field-Sight-with-Vigabatrin-During-I/ArticleNewsFeed/Article/detail/580874?contextCategoryId=41815&ref=25 Administration of the anti-epileptic drug vigabatrin during infancy compared with later ages may reduce the risk of vigabatrin-attributed visual field loss, according to research published in the February issue of Epilepsia. 2009-02-11T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/072009/580874/babyface_SS36035.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/072009/580874null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Study-Examines-Factors-Related-to-Post-Traumatic-E/ArticleNewsFeed/Article/detail/580744?contextCategoryId=41815&ref=25 Long-term outcome of post-traumatic epilepsy following war-related brain injury, including persistence of seizures, is significantly impacted by whether or not a sphincter disturbance occurred during injury and the number of shrapnel pieces involved in the injury, according to research published in the February issue of the Journal of Neurosurgery. 2009-02-10T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/072009/580744/brainepilepsy.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/072009/580744null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Gene-Appears-to-Play-Role-in-Epilepsy-EEG-Trait/ArticleNewsFeed/Article/detail/578289?contextCategoryId=41815&ref=25 A mutation in a non-coding region of the Elongator Protein Complex 4 ELP4 gene appears to be associated with rolandic epilepsy, which is marked by nocturnal seizures that begin in childhood and remit in adolescence, according to research published online Jan. 28 in the European Journal of Human Genetics. 2009-01-29T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/052009/578289/brainepilepsy.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/052009/578289null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Possible-Link-Between-Epilepsy-Drug-and-Autism-Exa/ArticleNewsFeed/Article/detail/569749?contextCategoryId=41815&ref=25 Children born to mothers who took the epilepsy drug valproate during pregnancy may have an up to sevenfold increased risk of developing autism spectrum disorder compared to children who were not exposed to epilepsy drugs in utero, according to a report published in the Dec. 2 issue of Neurology. 2008-12-04T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/492008/569749/46072.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/492008/569749null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Surgery-Offers-Some-Epileptics-Life-Expectancy-Gai/ArticleNewsFeed/Article/detail/569166?contextCategoryId=41815&ref=25 Anterior temporal lobe resection can give patients with pharmacoresistant temporal lobe epilepsy longer life expectancy and better quality of life, provided they meet the criteria for surgery, researchers report in the Dec. 3 issue of the Journal of the American Medical Association. 2008-12-02T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/492008/569166/BRAIN.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/492008/569166null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Vimpat-lacosamide-Antiepileptic-drug-approved-as-a/ArticleStandard/Article/detail/569885?contextCategoryId=41815&ref=25 New molecular entity: Lacosamide (Vimpat), an antiepileptic drug, was approved on October 28, 2008, as adjunctive therapy in the treatment of partial-onset seizures in patients with epilepsy aged 17 years or older 2008-12-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/formulary/492008/569885null XML http://www.modernmedicine.com/modernmedicine/CME+Showcase/Differential-Diagnosis-and-Management-of-Bipolar-D/CME/Article/detail/639279?contextCategoryId=41815&ref=25 The goal of this educational activity is to improve recognition of bipolar disorder, particularly bipolar depression, in order to optimize pharmacologic and psychosocial treatment. 2008-12-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/cme/modernmedicine/452009/639279null REMOTE http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Brain-Immune-Interactions-Important-in-Epilepsy/ArticleNewsFeed/Article/detail/568104?contextCategoryId=41815&ref=25 Interactions between immune cells and blood vessels in the brain contribute to the pathogenesis of epilepsy, and inhibiting these interactions can reduce or prevent seizures, according to research published online Nov. 23 in Nature Medicine. 2008-11-24T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/482008/568104/brainepilepsy.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/482008/568104null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Perilesional-Brain-Edema-Associated-with-Seizures/ArticleNewsFeed/Article/detail/564066?contextCategoryId=41815&ref=25 Perilesional edema is a common occurrence associated with episodic seizures in patients with calcified neurocysticercosis, an infection with the larval form of Taenia solium, according to a report published online Nov. 4 in The Lancet Neurology. 2008-11-06T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/452008/564066/brainepilepsy.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/452008/564066null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/CHEST-2008-Anti-Seizure-Drug-Increases-Death-Risk/ArticleNewsFeed/Article/detail/561710?contextCategoryId=41815&ref=25 In patients with refractory status epilepticus, treatment with the anti-seizure drug propofol may significantly increase the risk of mortality and morbidity, according to research presented this week at CHEST 2008, the 74th annual international scientific assembly of the American College of Chest Physicians, in Philadelphia. 2008-10-28T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/442008/561710/IV_59158.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/442008/561710null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Surgery-May-Benefit-Some-Epileptic-Children/ArticleNewsFeed/Article/detail/550329?contextCategoryId=41815&ref=25 Up to 30 percent of epileptic children have medically refractory epilepsy and may benefit from surgery, according to a review published in the September issue of Neurosurgical Focus. 2008-09-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/382008/550329/pediatrician_18031.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/382008/550329null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/3-T-MRI-Holds-Advantage-in-Epilepsy-Assessment/ArticleNewsFeed/Article/detail/549587?contextCategoryId=41815&ref=25 MRI at 3 T was associated with better rates of lesion detection and accurate assessment of lesions than 1.5-T MRI in evaluating epilepsy, according to research published in the September issue of the American Journal of Roentgenology. 2008-09-12T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/372008/549587/MIC090.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/372008/549587null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Epilepsy-Patients-at-Significant-Risk-of-Drowning/ArticleNewsFeed/Article/detail/543474?contextCategoryId=41815&ref=25 Epilepsy increases drowning risk by 15- to 19-fold compared with risk among those in the general population, according to the results of a study published in the Aug. 19 issue of Neurology. 2008-08-20T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/342008/543474/45239.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/342008/543474null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Nearly-1-Percent-of-US-Adults-Have-Active-Epilepsy/ArticleNewsFeed/Article/detail/535208?contextCategoryId=41815&ref=25 Nearly one in every 100 American adults has active epilepsy, and more than one-third of them are not receiving adequate treatment, according to a report from the U.S. Centers for Disease Control and Prevention published in the Aug. 8 issue of the Morbidity and Mortality Weekly Report. 2008-08-11T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/332008/535208/brainepilepsy.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/332008/535208null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Children-Face-Higher-Mortality-After-Febrile-Seizu/ArticleNewsFeed/Article/detail/534827?contextCategoryId=41815&ref=25 Children may face an increased risk of death in the two years following some febrile seizures, researchers report in the Aug. 9 issue of The Lancet. 2008-08-08T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/322008/534827/temperature_40027.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/322008/534827null XML http://www.modernmedicine.com/modernmedicine/Locum+Tenens/Generic-Depakote-approved/ArticleStandard/Article/detail/534610?contextCategoryId=41815&ref=25 Last month, the FDA passed the first generic forms of Depakote (divalproex solidum. 2008-08-07T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/locumlife/322008/534610null HTML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Topiramate-Therapy-During-Pregnancy-Raises-Concern/ArticleNewsFeed/Article/detail/531181?contextCategoryId=41815&ref=25 The use of topiramate as monotherapy or as an adjunct to other treatment for epilepsy during pregnancy raises some concerns about the increased risk of congenital malformation, according to a report published in the July 22 issue of Neurology. 2008-07-22T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/302008/531181/pregnant_SS36033.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/302008/531181null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Non-Adherence-Raises-Mortality-Risk-for-Epilepsy-P/ArticleNewsFeed/Article/detail/525066?contextCategoryId=41815&ref=25 Epilepsy patients who regularly fail to take their anti-epileptic drugs have increased risks of mortality and serious clinical events, according to a study published online June 18 in Neurology. 2008-06-19T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/252008/525066/elderlypatient_18265.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/252008/525066null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/ASIC1a-May-Have-Role-in-Stopping-Seizures/ArticleNewsFeed/Article/detail/523306?contextCategoryId=41815&ref=25 Adding to previous discoveries linking acidosis with seizure inhibition, investigations with mice found that acid-sensing ion channel 1a (ASIC1a) may mediate the seizure-terminating effects when brain pH falls, according to research published online June 8 in Nature Neuroscience. 2008-06-11T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/242008/523306/mouse.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/242008/523306null XML http://www.modernmedicine.com/modernmedicine/Neurology/Researchers-Find-Childhood-Epilepsy-Genetic-Link/ArticleNewsFeed/Article/detail/522013?contextCategoryId=41815&ref=25 Mutations in the GABAA receptor β3 subunit gene (GABRB3) are implicated in childhood absence epilepsy, according to research published online May 29 in the American Journal of Human Genetics. 2008-06-05T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/232008/522013/brainepilepsy.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/232008/522013null XML http://www.modernmedicine.com/modernmedicine/Neurology/Epilepsy/CustomizableHandout/Article/detail/554744?contextCategoryId=41815&ref=25 Epilepsy is a brain disorder involving repeated spontaneous seizures of any type. 2008-05-29T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/customizablehandout/modernmedicine/402008/554744null XML http://www.modernmedicine.com/modernmedicine/Neurology/Ketogenic-Diet-May-Reduce-Seizures-in-Epileptic-Ch/ArticleNewsFeed/Article/detail/514715?contextCategoryId=41815&ref=25 A ketogenic diet high in fat and low in carbohydrates reduces seizures in epileptic children with daily seizures who have failed other treatments, according to research published online May 3 in The Lancet Neurology. 2008-05-05T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/192008/514715/13520038.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/192008/514715null XML http://www.modernmedicine.com/modernmedicine/Primary+Care+Medicine/Prenatal-Exposure-to-Illness-May-Raise-Epilepsy-Ri/ArticleNewsFeed/Article/detail/514577?contextCategoryId=41815&ref=25 Prenatal exposure to a range of maternal infections, including vaginal yeast infections, cystitis, pyelonephritis, diarrhea and cough, is associated with an increased risk for epilepsy, according to the results of a study published in the May issue of Pediatrics. 2008-05-05T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/192008/514577/40274.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/192008/514577null XML http://www.modernmedicine.com/modernmedicine/Orthopedics/Phenytoin-Accelerates-Bone-Loss-in-Premenopausal-W/ArticleNewsFeed/Article/detail/512992?contextCategoryId=41815&ref=25 In premenopausal women with epilepsy, phenytoin monotherapy is associated with a significant loss of bone mineral density over a one-year period, according to the results of a study published in the April 29 issue of Neurology. 2008-04-29T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/182008/512992/OSTEO.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/182008/512992null XML http://www.modernmedicine.com/modernmedicine/Geriatrics/Epilepsys-Effect-on-Brain-Aging-Poorly-Understood/ArticleNewsFeed/Article/detail/511491?contextCategoryId=41815&ref=25 Although there is a paucity of data examining the effect of chronic epilepsy on cognitive and brain aging, available evidence suggests that individuals with chronic epilepsy may be at increased risk for dementia, according to an article published in the current issue of Epilepsia. 2008-04-21T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/172008/511491/brainepilepsy.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/172008/511491null XML http://www.modernmedicine.com/modernmedicine/Treatment+Areas/Mandatory-generic-substitution-continues-to-be-que/ArticleStandard/Article/detail/500078?contextCategoryId=41815&ref=25 More bills are being proposed that bar pharmacists from substituting antiepileptic drugs and immunosuppressants. 2008-03-10T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/drugtopics/102008/500078null XML http://www.modernmedicine.com/modernmedicine/Treatment+Areas/FDA-Antiepileptics-are-linked-to-increased-risk-of/ArticleStandard/Article/detail/488909?contextCategoryId=41815&ref=25 FDA finds increased risk of suicide in patients taking seizure drugs 2008-02-04T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/drugtopics/062008/488909null HTML http://www.modernmedicine.com/modernmedicine/Pediatrics/Episodic-pain-in-a-school-aged-child/ArticleStandard/Article/detail/479776?contextCategoryId=41815&ref=25 A 5-year-old presents with a history of episodic abdominal pain that is diagnosed as abdominal epilepsy stemming from a right temporal ganglioglioma. 2007-12-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/contpeds/512007/479776null XML http://www.modernmedicine.com/modernmedicine/Neurology/Multiple-Aura-Seizures-Signal-Surgical-Candidates/ArticleStandard/Article/detail/539502?contextCategoryId=41815&ref=25 CLEVELAND -- If patients experience different types of auras during a seizure, their epilepsy may arise from a single region of the brain, making them good candidates for surgery, researchers here said. 2007-08-21T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/332008/539502null XML http://www.modernmedicine.com/modernmedicine/Neurology/Seizures/CustomizableHandout/Article/detail/551362?contextCategoryId=41815&ref=25 A seizure is a sudden change in behavior due to an excessive electrical activity in the brain. 2007-08-06T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/customizablehandout/modernmedicine/382008/551362null XML http://www.modernmedicine.com/modernmedicine/Clinical+News/Lamotrigine-valproate-emerge-as-superior-epilepsy-/ArticleStandard/Article/detail/449553?contextCategoryId=41815&ref=25 The results of the Standard and New Antiepileptic Drugs (SANAD) trial, an unblinded, randomized, controlled, 2-arm study comparing the efficacy of various epilepsy drugs showed that for treatment of patients with partial seizures, lamotrigine demonstrated superior efficacy. 2007-08-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/formulary/332007/449553null XML http://www.modernmedicine.com/modernmedicine/CME+Showcase/Epilepsy-American-College-of-Physicians-PIER-CME/CME/Article/detail/619705?contextCategoryId=41815&ref=25 2007-07-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/cme/modernmedicine/342009/619705null REMOTE http://www.modernmedicine.com/modernmedicine/CME+Showcase/Febrile-Seizures-Pediatrics-American-College-of-Ph/CME/Article/detail/619740?contextCategoryId=41815&ref=25 2007-07-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/cme/modernmedicine/342009/619740null REMOTE http://www.modernmedicine.com/modernmedicine/Neurology/Single-Neonatal-Seizure-May-Have-Long-Term-Effects/ArticleNewsFeed/Article/detail/427945?contextCategoryId=41815&ref=25 Neonatal seizures can have long-lasting negative consequences on memory, according to the results of a study in rats published in the May issue of the Annals of Neurology. 2007-05-18T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/202007/427945/BRAINsmall.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/202007/427945null XML http://www.modernmedicine.com/modernmedicine/Neurology/Genes-Linked-to-Childhood-Febrile-Seizures/ArticleNewsFeed/Article/detail/422043?contextCategoryId=41815&ref=25 Genes located on chromosomes 3 and 18 are associated with childhood febrile seizures and epilepsy, according to the results of a study of a large French family published in the April 24 issue of Neurology. 2007-04-24T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/172007/422043/girlsick_18196.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/172007/422043null XML http://www.modernmedicine.com/modernmedicine/Neurology/Sodium-Butyrate-Stops-Seizures-in-Child-With-GPI-D/ArticleNewsFeed/Article/detail/421133?contextCategoryId=41815&ref=25 Sodium butyrate can stimulate expression of the PIGM gene and may cause complete cessation of intractable seizures in patients with inherited glycosylphosphatidylinositol (GPI) deficiencies, according to a pediatric case study in the April 19 issue of the New England Journal of Medicine. 2007-04-19T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/162007/421133/genetics_59175.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/162007/421133null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Which-Hormonal-Contraceptive-for-a-Patient-Taking-/ArticleStandard/Article/detail/541609?contextCategoryId=41815&ref=25 My 32-year-old patient has a seizure disorder that is treated with phenytoin. She wants to use hormonal contraception. Which agents will not interact with phenytoin? 2007-04-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/332008/541609null XML http://www.modernmedicine.com/modernmedicine/Treatment+Areas/Latebreakers-Keppra-gets-another-epilepsy-indicati/ArticleStandard/Article/detail/415067?contextCategoryId=41815&ref=25 Patients six years of age and older with primary generalized tonic-clonic seizures can now use levetiracetam (Keppra, UCB) as an adjunctive therapy to treat their epilepsy. 2007-04-02T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/drugtopics/132007/415067null XML http://www.modernmedicine.com/modernmedicine/Adolescent+Medicine/Web-links-Pediatric-seizure-info/ArticleStandard/Article/detail/421811?contextCategoryId=41815&ref=25 Not every child who has a first or second seizure will have a third, but some some will. These sites will hopefully help an epileptic child grow up to be the next Socrates, Van Gogh, or Dostoyevsky–all of who had epilepsy as well 2007-04-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/contpeds/172007/421811null XML http://www.modernmedicine.com/modernmedicine/Neurology/Study-Suggests-Lamotrigine-Is-Drug-of-Choice-for-E/ArticleNewsFeed/Article/detail/413908?contextCategoryId=41815&ref=25 Lamotrigine is a better, cost-effective alternative to the standard drug treatment for partial-onset epilepsy, carbamazepine, according to the results of a randomized trial of five different medications published in the March 24 issue of The Lancet. 2007-03-23T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/122007/413908/pills_18145.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/122007/413908null XML http://www.modernmedicine.com/modernmedicine/Neurology/Convulsions/CustomizableHandout/Article/detail/544677?contextCategoryId=41815&ref=25 Convulsions are when a person's body shakes rapidly and uncontrollably. During convulsions, the person's muscles contract and relax repeatedly. 2007-01-16T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/customizablehandout/modernmedicine/352008/544677null XML http://www.modernmedicine.com/modernmedicine/Neurology/Generalized-tonic-clonic-seizure/CustomizableHandout/Article/detail/554745?contextCategoryId=41815&ref=25 A generalized tonic-clonic seizure is a seizure involving the entire body, which usually involves muscle rigidity, violent muscle contractions, and loss of consciousness. 2006-11-21T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/customizablehandout/modernmedicine/402008/554745null XML http://www.modernmedicine.com/modernmedicine/Enews/Migraine-seizure-drug-may-increase-kidney-stone-ri/ArticleStandard/Article/detail/385985?contextCategoryId=41815&ref=25 Topiramate (Topamax), a drug commonly prescribed to treat seizures and migraines, can increase the propensity for calcium phosphate kidney stones, according to a study by researchers at the University of Texas Southwestern Medical Center in Dallas. 2006-11-16T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/urologytimes/462006/385985null HTML http://www.modernmedicine.com/modernmedicine/Neurology/Epilepsy---resources/CustomizableHandout/Article/detail/546271?contextCategoryId=41815&ref=25 Resources - epilepsy 2006-10-11T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/customizablehandout/modernmedicine/352008/546271null XML http://www.modernmedicine.com/modernmedicine/Ob%2FGyn+Surgery/New-momentum-on-building-a-medical-home-for-the-ch/ArticleStandard/Article/detail/378636?contextCategoryId=41815&ref=25 Care provided by a primary care practice that embraces the medical home model is better organized, more accessible, and less stressful to coordinate—so say parents of children who have special health-care needs. Here is a look at how you and your practice benefit from providing family-centered care within the medical home model. 2006-10-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/contpeds/412006/378636null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Epileptic-Emergencies-Early-Treatment-Can-Make-a-D/ArticleStandard/Article/detail/538364?contextCategoryId=41815&ref=25 Early acute treatment of epileptic emergencies may help prevent brain damage. The longer one waits to treat, the higher the chance for morbidity and mortality. 2006-09-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/332008/538364null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Epileptic-Emergencies-Early-Treatment-Can-Make-a-D/ArticleStandard/Article/detail/538291?contextCategoryId=41815&ref=25 2006-09-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/332008/538291null XML http://www.modernmedicine.com/modernmedicine/Patientcareonline.com+Exclusives/Convulsive-status-epilepticus-in-children/ArticleStandard/Article/detail/371892?contextCategoryId=41815&ref=25 2006-09-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/patcare/372006/371892null XML http://www.modernmedicine.com/modernmedicine/Neurology/Partial-focal-seizure/CustomizableHandout/Article/detail/554747?contextCategoryId=41815&ref=25 A partial seizure is an episode of abnormal electrical activity in one specific part of the brain. 2006-08-07T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/customizablehandout/modernmedicine/402008/554747null XML http://www.modernmedicine.com/modernmedicine/Neurology/Petit-mal-seizure/CustomizableHandout/Article/detail/554746?contextCategoryId=41815&ref=25 A petit mal seizure is a temporary disturbance of brain function caused by abnormal electrical activity in the brain and characterized by abrupt, short-term lack of conscious activity ("absence") or other abnormal change in behavior. 2006-08-07T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/customizablehandout/modernmedicine/402008/554746null XML http://www.modernmedicine.com/modernmedicine/Features/Whats-the-evidence-on-treating-disease-with-vitami/ArticleStandard/Article/detail/334359?contextCategoryId=41815&ref=25 The third of a four-part series on nutritional interventions examines vitamin C and megavitamin therapy. 2006-06-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/contpeds/242006/334359null XML http://www.modernmedicine.com/modernmedicine/Features/What-to-tell-parents-about-low-carbohydrate-dietin/ArticleStandard/Article/detail/318491?contextCategoryId=41815&ref=25 The first article of a four-part series on nutritional interventions examines evidence on the use, safety and efficacy of low-carbohydrate dieting for weight loss and intractable epilespy. 2006-04-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Puzzler/Swift-evolution-Ten-minutes-takes-a-boy-from-otiti/ArticleStandard/Article/detail/312581?contextCategoryId=41815&ref=25 What caused a tonic-clonic seizure? 2006-03-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Obstetrics/CRITICAL-CARE-in-OB-PART-2-Managing-an-eclamptic-s/ArticleStandard/Article/detail/312562?contextCategoryId=41815&ref=25 Few ob/gyns are prepared for the terrifying sight of a pregnant woman in the throes of an eclamptic convulsion. You can't predict which preeclamptic patients will go on to develop life-threatening eclampsia. But when they do, you can be ready to follow these seven important steps for stabilization and induction of labor within 24 hours. 2006-03-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Neurology/Epilepsy-in-older-adults/ArticleStandard/Article/detail/256510?contextCategoryId=41815&ref=25 Given that that the average person has one chronic illness for each decade over age 50, one would expect that patients who develop seizures in late life would have associated medical and/or neurologic conditions. Cerebrovascular disease, hypertension, heart disease, diabetes mellitus, renal disease, and dementia all relate to epilepsy. Co-morbidities not only contribute to the causation and consequences of seizures, they also interfere with effective treatment and optimal functioning. Because seizures in older individuals can lead to serious consequences, safe and effective treatment is essential. Yet, antiepileptic drugs (AEDs) may cause adverse effects that may be worse in older patients when compared to younger patients. Multiple medications lead to a high probability that medically significant drug interactions may occur and must be monitored for in geriatric patients. 2005-12-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/In+This+Issue/Epilepsy-drug-treats-breast-cancer-related-hot-fla/ArticleStandard/Article/detail/254748?contextCategoryId=41815&ref=25 Gabapentin at a dosage of 900 mg/day, but not at 300 mg/day, provides effective relief of hot flashes in women with breast cancer. 2005-12-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/CME/Diagnosing-epilepsy-in-older-adults-What-does-it-m/ArticleStandard/Article/detail/184866?contextCategoryId=41815&ref=25 Acute and chronic seizures (epilepsy) occur frequently in older adults. However, despite its high prevalence, epilepsy is often overlooked or misdiagnosed because seizures mimic other common conditions in the aged. Recognizing and correctly diagnosing seizures can lead to a number of effective treatments. 2005-10-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/geriatrics/412005/184866/CME_Bug_thumbnail.jpg http://www.modernmedicine.com/modernmedicine/data/articlestandard/geriatrics/412005/184866/CME_Bug_main.jpg XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Skull-Depression/ArticleStandard/Article/detail/536462?contextCategoryId=41815&ref=25 A 5-month-old boy's head hit the floor after he tumbled from his mother's arms. 2005-09-14T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/332008/536462null XML http://www.modernmedicine.com/modernmedicine/Cardiovascular+disease/Syncope-in-the-elderly-patient-Common-and-uncommon/ArticleStandard/Article/detail/165984?contextCategoryId=41815&ref=25 Because the causes of syncope vary across age-groups, diagnostic testing should be guided by a differential focused on diseases common in the patient's group. 2005-06-01T04:00:00Z XML http://www.modernmedicine.com/modernmedicine/Neurologic+Disorders/Topics-in-Neurology-Advances-in-managing-epilepsy/ArticleStandard/Article/detail/147332?contextCategoryId=41815&ref=25 Even with newer medications and surgical options, the goal of optimal patient management remains the same: seizure free without side effects. 2005-02-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Patientcareonline.com+Exclusives/Focus-on-women-with-epilepsy/ArticleStandard/Article/detail/147341?contextCategoryId=41815&ref=25 Special issues for young women with epilepsy include contraception, pregnancy planning, teratogenicity, parenting, and breastfeeding. 2005-02-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Features/Severe-brain-injury-Helping-patient-and-family-on-/ArticleStandard/Article/detail/143316?contextCategoryId=41815&ref=25 Traumatic brain injury affects virtually every aspect of the patient's—and family's—life. Here's what to expect in the aftermath and how to help the family deal with the often overwhelming demands of rehabilitation and return to home and community. 2005-01-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Teratogens/Epilepsy-and-pregnancy-minimizing-the-risks/ArticleStandard/Article/detail/114166?contextCategoryId=41815&ref=25 Does maternal epilepsy increase the risk of congenital malformations, or are the antiepileptic drugs to blame? Either way, the primary goal of therapy during pregnancy is to control a woman's seizures while minimizing fetal exposure to anticonvulsive drugs. 2004-01-01T05:00:00Z HTML http://www.modernmedicine.com/modernmedicine/Endocrinology/Dupuytren-Disease/ArticleStandard/Article/detail/535769?contextCategoryId=41815&ref=25 For 3 years, a linear plaque had been slowly developing on the left palm of a 47-year-old woman who had difficulty in opening and closing her hand. There was no contributory family history. 2003-11-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/332008/535769null XML http://www.modernmedicine.com/modernmedicine/Hormones/Cover-Story-When-a-chronically-ill-patient-needs-c/ArticleStandard/Article/detail/114768?contextCategoryId=41815&ref=25 While some hormonal contraceptives are clearly contraindicated in specific chronic disorders, others pose little or no threat for the same condition. To provide practical guidelines on the subject, two experts review the "WHO Medical Eligibility Criteria for Contraceptive Use." 2003-10-01T04:00:00Z HTML http://www.modernmedicine.com/modernmedicine/Preeclampsia/A-role-for-expectant-management-in-severe-preeclam/ArticleStandard/Article/detail/139464?contextCategoryId=41815&ref=25 Although controversial, delivery is usually recommended for all women with severe preeclampsia--regardless of gestational age. But premature delivery can pose a major threat to the periviable fetus. When is it appropriate to expectantly manage severe preeclampsia? 2002-12-01T05:00:00Z HTML