http://www.modernmedicine.com/modernmedicine/Multiple+Sclerosis/Article/list/41155 Modern Medicine is a healthcare professional resource dedicated to providing information about Multiple Sclerosis, and other medical conditions. 2009-11-21T20:54:05Z http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/MRI-Found-to-Be-Useful-in-Predicting-Multiple-Scle/ArticleNewsFeed/Article/detail/641147?contextCategoryId=41155&ref=25 In patients with a clinically isolated syndrome treated with interferon beta-1b, the modified Barkhof criteria may provide some value in predicting conversion to clinically definite multiple sclerosis, according to a multicenter, randomized study published in the November issue of the Archives of Neurology. 2009-11-11T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/462009/641147/BRAIN.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/462009/641147null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Adolescent-Obesity-Linked-to-MS-Risk-in-Women/ArticleNewsFeed/Article/detail/640676?contextCategoryId=41155&ref=25 Women who were obese in adolescence are at higher risk of multiple sclerosis as adults, according to a study in the Nov. 10 issue of Neurology. 2009-11-10T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/462009/640676/teen_girl.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/462009/640676null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Early-MS-Relapses-Linked-to-Short-Term-Risk-of-Pro/ArticleNewsFeed/Article/detail/639704?contextCategoryId=41155&ref=25 Early relapses of multiple sclerosis pose more short-term risk of disease progression than long-term consequences, according to a Canadian retrospective review published online Nov. 4 in Neurology. 2009-11-05T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/452009/639704/cane_SS36051.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/452009/639704null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Interferon-Beta-Effects-Explored-in-Multiple-Scler/ArticleNewsFeed/Article/detail/634418?contextCategoryId=41155&ref=25 The effects of interferon beta on chemokine receptor genes and chemokine expression in peripheral immune cells may provide the therapeutic effect seen in multiple sclerosis treatment, according to a German study in the October issue of the Archives of Neurology. 2009-10-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/422009/634418/mic027.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/422009/634418null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Glatiramer-Acetate-May-Delay-Multiple-Sclerosis-On/ArticleNewsFeed/Article/detail/632908?contextCategoryId=41155&ref=25 Early treatment with glatiramer acetate may delay the start of clinically definite multiple sclerosis, according to the PreCISe study published online Oct. 7 in The Lancet. 2009-10-08T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/412009/632908/40265.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/412009/632908null XML http://www.modernmedicine.com/modernmedicine/Pathology/Viruria-Could-Help-Predict-Rare-Condition-in-Multi/ArticleNewsFeed/Article/detail/625286?contextCategoryId=41155&ref=25 Analyzing the urine of multiple sclerosis patients for JC virus could help identify those at risk of developing another rare demyelinating disease after natalizumab (Tysabri) treatment, according to a study in the Sept. 10 issue of the New England Journal of Medicine. 2009-09-09T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/372009/625286/33082.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/372009/625286null XML http://www.modernmedicine.com/modernmedicine/CME+Showcase/Multiple-Sclerosis-Case-3-Ms-LD-a-24-Year-Old-Woma/CME/Article/detail/638988?contextCategoryId=41155&ref=25 Multiple sclerosis (MS) is a severely disabling, chronic condition that often strikes adults in the prime of their lives. Those suffering from MS may require permanent and continual therapy to maintain or optimize their functional capacities. Research has shown that early therapeutic intervention and maintenance of long-term medical treatment helps slow the disease, which typically progresses even during asymptomatic periods if left untreated. 2009-09-09T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/cme/modernmedicine/452009/638988null REMOTE http://www.modernmedicine.com/modernmedicine/CME+Showcase/Multiple-Sclerosis-Case-1-Mrs-TM-a-40-Year-Old-Wom/CME/Article/detail/638978?contextCategoryId=41155&ref=25 Multiple sclerosis (MS) is a severely disabling, chronic condition that often strikes adults in the prime of their lives. Those suffering from MS may require permanent and continual therapy to maintain or optimize their functional capacities. 2009-09-09T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/cme/modernmedicine/452009/638978null REMOTE http://www.modernmedicine.com/modernmedicine/CME+Showcase/Multiple-Sclerosis-Case-1-Mrs-TM-a-40-Year-Old-Wom/CME/Article/detail/640912?contextCategoryId=41155&ref=25 Those suffering from MS may require permanent and continual therapy to maintain or optimize their functional capacities. Research has shown that early therapeutic intervention and maintenance of long-term medical treatment helps slow the disease, which typically progresses even during asymptomatic periods if left untreated. 2009-09-09T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/cme/modernmedicine/462009/640912null REMOTE http://www.modernmedicine.com/modernmedicine/CME+Showcase/Multiple-Sclerosis-Case-2-Ms-MW-a-38-Year-Old-Woma/CME/Article/detail/638984?contextCategoryId=41155&ref=25 Multiple sclerosis (MS) is a severely disabling, chronic condition that often strikes adults in the prime of their lives. Those suffering from MS may require permanent and continual therapy to maintain or optimize their functional capacities. 2009-09-09T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/cme/modernmedicine/452009/638984null REMOTE http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Smoking-Linked-to-Higher-Multiple-Sclerosis-Risk/ArticleNewsFeed/Article/detail/623692?contextCategoryId=41155&ref=25 Smokers may face a higher risk of developing multiple sclerosis, but the risk increase may not be due to nicotine, according to research published in the Sept. 1 issue of Neurology. 2009-09-02T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/362009/623692/BRAIN.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/362009/623692null XML http://www.modernmedicine.com/modernmedicine/CME+Showcase/Sound-Strategies-for-Multiple-Sclerosis-The-Longer/CME/Article/detail/638991?contextCategoryId=41155&ref=25 Those suffering from MS may require permanent and continual therapy to maintain or optimize their functional capacities. Research has shown that early therapeutic intervention and maintenance of long-term medical treatment helps slow the disease, which typically progresses even during asymptomatic periods if left untreated. 2009-09-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/cme/modernmedicine/452009/638991null REMOTE http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Breast-Feeding-May-Lower-Multiple-Sclerosis-Relaps/ArticleNewsFeed/Article/detail/620816?contextCategoryId=41155&ref=25 New mothers with multiple sclerosis who breast-feed exclusively may have a lower risk of postpartum MS relapses, according to research published in the August issue of the Archives of Neurology. 2009-08-21T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/342009/620816/46044.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/342009/620816null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Smoking-May-Increase-Brain-Injury-in-Multiple-Scle/ArticleNewsFeed/Article/detail/619795?contextCategoryId=41155&ref=25 In patients with multiple sclerosis, smokers are more likely to have increased blood-brain barrier disruption, lesion volumes and brain atrophy, according to a study in the Aug. 18 issue of Neurology. 2009-08-18T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/342009/619795/SS42028.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/342009/619795null XML http://contemporarypediatrics.modernmedicine.com/contpeds/Adolescent+Medicine+Top+Story/An-integrated-model-for-palliative-care/ArticleStandard/Article/detail/615278?contextCategoryId=41155&ref=25 The words "hospice" and "palliative care" have long made parents cringe -- and they might scare off some pediatricians, too. 2009-07-30T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/contpeds/312009/615278null HTML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Predictors-Identified-for-Progression-of-Benign-MS/ArticleNewsFeed/Article/detail/615288?contextCategoryId=41155&ref=25 Cognitive assessment tests and conventional magnetic resonance imaging can predict future disease progression in patients with benign multiple sclerosis, according to a study published online July 29 in Neurology. 2009-07-30T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/312009/615288/BRAIN.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/312009/615288null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Smoking-Linked-to-More-Rapid-Multiple-Sclerosis-Pr/ArticleNewsFeed/Article/detail/611376?contextCategoryId=41155&ref=25 Patients with multiple sclerosis who smoke have worse disease and develop progressive disease faster than nonsmokers, according to a study in the July issue of the Archives of Neurology. 2009-07-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/292009/611376/HCH053.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/292009/611376null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Breast-Feeding-May-Reduce-Risk-of-Multiple-Scleros/ArticleNewsFeed/Article/detail/602760?contextCategoryId=41155&ref=25 Exclusive breast-feeding and the delayed return of menstruation that comes with it can reduce the risk of postpartum relapse of multiple sclerosis, according to a study reported online June 8 in the Archives of Neurology. 2009-06-10T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/242009/602760/breastfeed.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/242009/602760null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/AAN-Multiple-Sclerosis-Drugs-Show-Harm-Benefit/ArticleNewsFeed/Article/detail/595978?contextCategoryId=41155&ref=25 In multiple sclerosis, mitoxantrone treatment is associated with a higher-than-expected risk of leukemia, but combined treatment with methylprednisolone and interferon-beta 1a is associated with more beneficial effects on disease activity than interferon alone, according to two studies presented at the annual meeting of the American Academy of Neurology, held April 25 to May 2 in Seattle, and a study published online April 30 in The Lancet Neurology. 2009-04-30T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/182009/595978/prescriptions_40050.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/182009/595978null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Stem-Cells-Offer-Potential-Multiple-Sclerosis-Trea/ArticleNewsFeed/Article/detail/593198?contextCategoryId=41155&ref=25 Oligodendrocytes generated from human embryonic stem cells that produce myelin offer novel possibilities for basic and clinical research into treatments for multiple sclerosis, but the process is more protracted than in mouse cells, according to a study published online April 10 in Development. 2009-04-13T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/162009/593198/cells_59245.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/162009/593198null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Lower-Cancer-Risk-Seen-in-Multiple-Sclerosis-Patie/ArticleNewsFeed/Article/detail/590668?contextCategoryId=41155&ref=25 Patients with multiple sclerosis have an overall lower cancer risk, which does not appear to be due to heredity, according to the results of a study published in the March 31 issue of Neurology. 2009-03-31T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/142009/590668/18163.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/142009/590668null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/AAN-Breast-Feeding-Benefits-Multiple-Sclerosis-Pat/ArticleNewsFeed/Article/detail/582762?contextCategoryId=41155&ref=25 In new mothers with multiple sclerosis, exclusive breast-feeding may significantly reduce the risk of postpartum relapses, according to research that will be presented April 25-May 2 at the annual meeting of the American Academy of Neurology in Seattle. 2009-02-20T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/082009/582762/whi058.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/082009/582762null XML http://www.modernmedicine.com/modernmedicine/Pathology/Stem-Cell-Transplantation-Shows-Benefit-in-MS/ArticleNewsFeed/Article/detail/578836?contextCategoryId=41155&ref=25 Autologous non-myeloablative hemopoietic stem cell transplantation may prevent neurological progression and improve neurological disability in relapsing-remitting multiple sclerosis, according to research published online Jan. 30 in The Lancet Neurology. 2009-02-02T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/062009/578836/cane_SS36051.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/062009/578836null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Relapses-More-Common-in-Pediatric-Onset-Multiple-S/ArticleNewsFeed/Article/detail/575171?contextCategoryId=41155&ref=25 Patients with pediatric-onset multiple sclerosis are more likely to experience relapses than those with adult-onset disease, suggesting that their disease course may be more inflammatory, according to study findings published in the January issue of the Archives of Neurology. 2009-01-13T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/032009/575171/nerves_18120.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/032009/575171null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Syndrome-Suggestive-of-Later-Multiple-Sclerosis/ArticleNewsFeed/Article/detail/571412?contextCategoryId=41155&ref=25 MRI anomalies are highly suggestive of demyelinating disease, and predictive of subsequent multiple sclerosis-related events, according to research published online Dec. 10 in Neurology. 2008-12-12T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/502008/571412/BRAIN.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/502008/571412null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Drug-Helps-Only-Half-of-Multiple-Sclerosis-Patient/ArticleNewsFeed/Article/detail/565613?contextCategoryId=41155&ref=25 Only half of multiple sclerosis patients treated with interferon beta have a full response to the drug, according to research published online Nov. 10 in the Archives of Neurology. 2008-11-12T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/462008/565613/cup_MIC017ML.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/462008/565613null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Alemtuzumab-effective-in-treating-early-MS-but-ass/ArticleStandard/Article/detail/562932?contextCategoryId=41155&ref=25 A phase 2 study published in the New England Journal of Medicine reported that alemtuzumab was more effective than interferon beta-1a in treating early, relapsing-remitting multiple sclerosis (MS), but the agent was also associated with higher rates of autoimmunity, including cases of immune thrombocytopenic purpura (ITP). 2008-11-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/formulary/452008/562932null XML http://www.modernmedicine.com/modernmedicine/CME+Showcase/Hot-Topics-In-Neuropathic-Pain-Progress-and-Possib/CME/Article/detail/638994?contextCategoryId=41155&ref=25 In the United States, 2% to 3% of the population is affected by neuropathic pain, with postherpetic neuralgia and diabetic peripheral neuropathic pain being the most common. Symptoms include allodynia, paresthesia, and hyperalgesia, as well as partial or complete loss of sensation and muscle weakness. The impact of neuropathic pain on a patient's quality of life is overwhelmingly negative. 2008-11-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/cme/modernmedicine/452009/638994null REMOTE http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Comorbidity-Related-to-Disability-in-Multiple-Scle/ArticleNewsFeed/Article/detail/562318?contextCategoryId=41155&ref=25 Both diagnostic delay and disability at diagnosis are influenced by comorbidity among multiple sclerosis patients, and these relationships need to undergo further study, according to a study published online Oct. 29 in Neurology. 2008-10-30T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/442008/562318/18163.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/442008/562318null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Phase-II-Trial-Finds-Drug-Helpful-in-Multiple-Scle/ArticleNewsFeed/Article/detail/561110?contextCategoryId=41155&ref=25 A phase II trial found that oral fumarate can reduce signs of disease activity in relapsing-remitting multiple sclerosis, according to research published in the Oct. 25 issue of The Lancet. 2008-10-24T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/432008/561110/cane_SS36051.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/432008/561110null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Immunosuppression-Has-Benefits-in-Early-Multiple-S/ArticleNewsFeed/Article/detail/560646?contextCategoryId=41155&ref=25 Aggressive immunosuppressive treatment with alemtuzumab greatly reduces the rate of relapse and disability in patients with early multiple sclerosis compared with interferon beta-1a, though with substantial adverse effects, according to a report in the Oct. 23 issue of the New England Journal of Medicine. 2008-10-22T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/432008/560646/walker_18129.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/432008/560646null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Hepatitis-B-Vaccine-Linked-to-Inflammatory-Demyeli/ArticleNewsFeed/Article/detail/557769?contextCategoryId=41155&ref=25 Although hepatitis B vaccination usually does not increase the risk of pediatric central nervous system inflammatory demyelination, the Engerix B vaccine may be associated with an increased risk, particularly for confirmed cases of multiple sclerosis, according to a report published online Oct. 8 in Neurology. 2008-10-09T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/412008/557769/vaccine.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/412008/557769null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/WCTRMS-Vitamin-D-Status-Linked-to-Multiple-Scleros/ArticleNewsFeed/Article/detail/552098?contextCategoryId=41155&ref=25 In children with a first demyelinating event, those with lower vitamin D levels are more likely to progress to multiple sclerosis, and the incidence of first demyelinating events is significantly greater at higher latitudes, where the sun's rays are weaker and vitamin D insufficiency is more common, according to research presented at the World Congress on Treatment and Research in Multiple Sclerosis held Sept. 17 to 20 in Montreal, Canada. 2008-09-22T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/392008/552098/sun.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/392008/552098null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/WCTRMS-Resveratrol-May-Be-Beneficial-in-Multiple-S/ArticleNewsFeed/Article/detail/551677?contextCategoryId=41155&ref=25 Resveratrol -- a natural polyphenol compound in red wine -- may help prevent the axonal degeneration characteristic of multiple sclerosis, according to research presented at the World Congress on Treatment and Research in Multiple Sclerosis held Sept. 17 to 20 in Montreal, Canada. 2008-09-19T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/382008/551677/dng015.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/382008/551677null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Modified-Mice-Less-Susceptible-to-Multiple-Scleros/ArticleNewsFeed/Article/detail/527605?contextCategoryId=41155&ref=25 Mice lacking a certain protein are less susceptible to developing a form of multiple sclerosis due to reduced migration of lymphocytes into the central nervous system, according to the results of a study published in the July 8 issue of the Proceedings of the National Academy of Sciences. 2008-07-02T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/272008/527605/mouse.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/272008/527605null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Multiple-Sclerosis-Drug-Reduces-Active-Lesions/ArticleNewsFeed/Article/detail/525348?contextCategoryId=41155&ref=25 In patients with relapsing-remitting multiple sclerosis, treatment with a higher dosage of laquinimod reduces the formation of active lesions and is well tolerated, according to the results of a study published in the June 21 issue of The Lancet. 2008-06-20T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/252008/525348/pills_59034.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/252008/525348null XML http://www.modernmedicine.com/modernmedicine/Treatment+Areas/Oral-treatment-reduces-multiple-sclerosis-flare-up/ArticleStandard/Article/detail/522790?contextCategoryId=41155&ref=25 The AAN annual meeting in Chicago, researchers reported advances in treatments for a variety of neurological diseases 2008-06-16T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/drugtopics/242008/522790null XML http://www.modernmedicine.com/modernmedicine/Internal+Medicine/Hereditary-Rickets-and-Multiple-Sclerosis-Linked/ArticleNewsFeed/Article/detail/523657?contextCategoryId=41155&ref=25 Hereditary rickets due to altered vitamin D metabolism is associated with multiple sclerosis, according to study findings published in the June issue of the Archives of Neurology. 2008-06-12T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/242008/523657/genetics_MIC028ML.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/242008/523657null XML http://www.modernmedicine.com/modernmedicine/Clinical+Meetings/Glatiramer-interferon-beta-1b-comparable-in-early-/ArticleStandard/Article/detail/520964?contextCategoryId=41155&ref=25 An investigational 500-mcg dose of interferon beta-1b demonstrated no advantage compared with the approved 250-mcg dose of interferon beta-1b or with glatiramer 20 mg in reducing relapse risk in patients with early relapsing-remitting multiple sclerosis (RRMS), said Paul O'Connor, MD, MS Program Director, St. Michael's Hospital, the University of Toronto, at the 60th Annual Meeting of the American Academy of Neurology, Chicago. 2008-06-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/formulary/232008/520964null XML http://www.modernmedicine.com/modernmedicine/Clinical+Meetings/Glatiramer-effective-in-delaying-clinical-MS/ArticleStandard/Article/detail/520962?contextCategoryId=41155&ref=25 Glatiramer represents a new option for delaying conversion of clinically isolated syndrome (CIS) to clinically definite multiple sclerosis (CDMS), according to the results of a new study known as PRECISE, presented at the 60th Annual Meeting of the American Academy of Neurology, Chicago. 2008-06-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/formulary/232008/520962null XML http://www.modernmedicine.com/modernmedicine/Neurology/Cognitive-Impairment-Common-in-Young-MS-Patients/ArticleNewsFeed/Article/detail/516656?contextCategoryId=41155&ref=25 Children and juveniles with multiple sclerosis (MS) may have an increased risk of cognitive impairment and low IQ scores, and low IQ scores may be especially associated with a younger age at onset, according to the results of a study published in the May 13 issue of Neurology. 2008-05-13T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/202008/516656/neckexam_40213.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/202008/516656null XML http://www.modernmedicine.com/modernmedicine/Neurology/Prozac-Shows-Promise-As-Multiple-Sclerosis-Treatme/ArticleNewsFeed/Article/detail/513866?contextCategoryId=41155&ref=25 A proof-of-concept trial of fluoxetine (Prozac) to treat relapsing multiple sclerosis has shown that it tends to reduce the formation of new lesions, according to a report published online May 1 in the Journal of Neurology, Neurosurgery and Psychiatry. 2008-05-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/182008/513866/prozac.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/182008/513866null XML http://www.modernmedicine.com/modernmedicine/Treatment+Areas/New-data-on-progressive-multifocal-leukoencephalop/ArticleStandard/Article/detail/511322?contextCategoryId=41155&ref=25 New data show no new cases of PML in Tysabri patients 2008-04-21T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/drugtopics/172008/511322null HTML http://www.modernmedicine.com/modernmedicine/Neurology/AAN-Oral-FTY720-Effective-in-Multiple-Sclerosis/ArticleNewsFeed/Article/detail/510413?contextCategoryId=41155&ref=25 In patients with relapsing multiple sclerosis, three years of treatment with oral FTY720 significantly reduces relapse rates and inflammatory activity, according to research presented this week at the annual meeting of the American Academy of Neurology in Chicago. 2008-04-16T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/162008/510413/man_walking_33011.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/162008/510413null XML http://www.modernmedicine.com/modernmedicine/Hypertension/ASI-Caffeine-Protects-Against-Multiple-Sclerosis-i/ArticleNewsFeed/Article/detail/508512?contextCategoryId=41155&ref=25 A dose of caffeine equivalent to that contained in six to eight cups of coffee appears to protect mice from developing an animal model of multiple sclerosis, according to research presented April 7 as part of the scientific program of the American Society of Immunologists at the Experimental Biology 2008 meeting in San Diego. 2008-04-08T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/152008/508512/mouse.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/152008/508512null XML http://www.modernmedicine.com/modernmedicine/Ophthalmology/Heating-and-Eye-Movements-Model-Nerve-Conduction-i/ArticleNewsFeed/Article/detail/505329?contextCategoryId=41155&ref=25 In multiple sclerosis (MS) patients with a particular defect in eye movement, whole-body heating further impairs ocular motor function that is restored after cooling, providing a model for changes in the fidelity of axonal conduction, according to a study published in the March 25 issue of Neurology. 2008-03-25T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/132008/505329/eye_SS36006.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/132008/505329null XML http://www.modernmedicine.com/modernmedicine/General+Ophthalmology/Brain-MRI-useful-for-predicting-risk-of-MS-in-opti/ArticleStandard/Article/detail/505812?contextCategoryId=41155&ref=25 Long-term outcomes of a study of optic neuritis have shown that even one brain lesion ≥3 mm at the time of the first episode can be predictive of development of multiple sclerosis, making a brain MRI an essential part of patient management. 2008-03-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/132008/505812null XML http://www.modernmedicine.com/modernmedicine/Managed+Care/FDA-Warns-of-Liver-Toxicity-with-Multiple-Sclerosi/ArticleNewsFeed/Article/detail/498835?contextCategoryId=41155&ref=25 The U.S. Food and Drug Administration together with Biogen Idec and Elan, the manufacturers of Tysabri (natalizumab), have issued warnings to health-care professionals of the risk of significant liver injury associated with Tysabri, a monoclonal antibody used in the treatment of multiple sclerosis. 2008-02-28T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092008/498835/40265.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092008/498835null XML http://www.modernmedicine.com/modernmedicine/Neurology/New-Therapeutic-Targets-for-Multiple-Sclerosis-Ide/ArticleNewsFeed/Article/detail/492408?contextCategoryId=41155&ref=25 Researchers have identified proteins uniquely expressed in brain lesions of individuals with multiple sclerosis that could represent potential therapeutic targets for the disease, according to a report published online Feb. 17 in Nature. 2008-02-18T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/082008/492408/mouse.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/082008/492408null XML http://www.modernmedicine.com/modernmedicine/Neurology/Multiple-sclerosis/CustomizableHandout/Article/detail/554785?contextCategoryId=41155&ref=25 Multiple sclerosis is an autoimmune disease that affects the central nervous system (the brain and spinal cord). 2007-08-06T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/customizablehandout/modernmedicine/402008/554785null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Interleukin-7-Receptor-Gene-Linked-to-Multiple-Scl/ArticleNewsFeed/Article/detail/533158?contextCategoryId=41155&ref=25 An international team of researchers has discovered that variants of the interleukin-7 receptor α (IL7Rα) gene increase the risk of multiple sclerosis. The findings were published online July 29 in two studies in Nature Genetics and confirmed in a third, which was released early by the New England Journal of Medicine. 2007-07-30T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/312008/533158/genetics_MIC028ML.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/312008/533158null XML http://www.modernmedicine.com/modernmedicine/Clinical+Meetings/From-the-American-Academy-of-Neurology-59th-Annual/ArticleStandard/Article/detail/442863?contextCategoryId=41155&ref=25 Rituximab, which is currently FDA-approved for the treatment of certain B-cell lymphomas and moderate-to-severe rheumatoid arthritis, demonstrated benefit in the treatment of relapsing-remitting multiple sclerosis (RRMS) in 2 early-phase experimental trials. 2007-07-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/formulary/292007/442863null XML http://www.modernmedicine.com/modernmedicine/Clinical+Meetings/From-the-American-Academy-of-Neurology-59th-Annual/ArticleStandard/Article/detail/442861?contextCategoryId=41155&ref=25 Immediate initiation of interferon beta-1b in patients with a first event suggestive of multiple sclerosis (MS) significantly reduces the risk of permanent neurologic impairment compared with delayed initiation, according to findings from the BENEFIT study presented during the AAN's 59th annual meeting. 2007-07-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/formulary/292007/442861null XML http://www.modernmedicine.com/modernmedicine/Multiple+Sclerosis/AAN-Early-MS-Treatment-with-Interferon-Beta-1b-Del/ArticleStandard/Article/detail/540645?contextCategoryId=41155&ref=25 BOSTON -- The risk of multiple sclerosis progression can be significantly reduced by starting patients on interferon beta-1b (Betaseron) before a diagnosis of MS is even confirmed, investigators reported here. 2007-05-02T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/332008/540645null XML http://www.modernmedicine.com/modernmedicine/Primary+Care+Medicine/CSF-Oligoclonal-Banding/CustomizableHandout/Article/detail/552994?contextCategoryId=41155&ref=25 CSF oligoclonal banding is a test to look for inflammation-related substances in the cerebrospinal fluid (CSF), the clear fluid that flows in the space surrounding the spinal cord and brain. 2007-04-30T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/customizablehandout/modernmedicine/392008/552994null XML http://www.modernmedicine.com/modernmedicine/Neurology/Interferon-beta-Slows-Multiple-Sclerosis-Progressi/ArticleNewsFeed/Article/detail/423494?contextCategoryId=41155&ref=25 In patients with relapsing-remitting multiple sclerosis, treatment with interferon-β significantly slows disease progression, according to a report published in the April issue of the Annals of Neurology. 2007-04-30T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/182007/423494/18129.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/182007/423494null XML http://www.modernmedicine.com/modernmedicine/Primary+Care+Medicine/Multiple-Sclerosis---Resources/CustomizableHandout/Article/detail/546250?contextCategoryId=41155&ref=25 Resources - multiple sclerosis 2006-11-09T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/customizablehandout/modernmedicine/352008/546250null XML http://www.modernmedicine.com/modernmedicine/Neuro-Ophthalmology/With-new-onset-nystagmus-in-adult-consider-MS/ArticleStandard/Article/detail/186749?contextCategoryId=41155&ref=25 Iowa City—Multiple sclerosis (MS) is associated with the development of various forms of nystagmus. The association is so strong that new-onset nystagmus in an adult should be considered MS until proven otherwise. 2005-10-15T04:00:00Z XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Multiple-Sclerosis/ArticleStandard/Article/detail/537064?contextCategoryId=41155&ref=25 Multiple sclerosis, the most common cause of disability among young adults, can take years to diagnose because symptoms may wax and wane over time, and patients may not initially seek evaluation. 2005-07-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/332008/537064null XML http://www.modernmedicine.com/modernmedicine/Column/Nystagmus-can-be-the-presenting-sign-of-multiple-s/ArticleStandard/Article/detail/157091?contextCategoryId=41155&ref=25 Multiple sclerosis (MS) can present to the ophthalmologist with visual loss (e.g., opticneuritis), diplopia (e.g., internuclear ophthalmoplegia [INO] or sixth-nerve palsy), or nystagmus. 2005-05-01T04:00:00Z XML http://www.modernmedicine.com/modernmedicine/Neurologic+Disorders/New-treatments-portend-a-hopeful-course-for-MS/ArticleStandard/Article/detail/160901?contextCategoryId=41155&ref=25 An array of treatment options enables many patients with multiple sclerosis to live with good functionality and quality of life. 2005-05-01T04:00:00Z XML http://www.modernmedicine.com/modernmedicine/Neurologic+Disorders/Save-time-with-the-5-minute-neurologic-exam/ArticleStandard/Article/detail/156074?contextCategoryId=41155&ref=25 In apparently healthy patients, you can usually perform a screening neurologic examination in less than 5 minutes. Don't risk missing a potentially important diagnosis for such a small expense of time. 2005-04-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/The+15-Minute+Visit/THE-15-MINUTE-VISIT-When-the-complaint-is-fatigue/ArticleStandard/Article/detail/156067?contextCategoryId=41155&ref=25 A guide to patient encounters in the real world of office practice 2005-04-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Gynecology/When-your-obgyn-patient-happens-to-be-disabled/ArticleStandard/Article/detail/145656?contextCategoryId=41155&ref=25 Roughly 30 million US women, young and old, are living with disabilities, and they need equal access to mammography, contraception, and ob/gyn exams. Special training in treating them would be ideal, but there are still practical ways to break down barriers and provide better care. 2005-02-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Pharmacy+Benefit/New-MS-infusion-drug-requires-careful-benefit-mana/ArticleStandard/Article/detail/133413?contextCategoryId=41155&ref=25 One particular disease state, multiple sclerosis (MS), deserves specific attention at this time because there are several therapeutic treatment options available today. 2004-11-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Neuro-Ophthalmology/Typical-optic-neuritis-may-signal-multiple-scleros/ArticleStandard/Article/detail/88645?contextCategoryId=41155&ref=25 Anaheim, CA-Typical optic neuritis may be the first indication of multiple sclerosis (MS). Recognizing this and the implications for treatment as well as determining the degree of risk of developing MS are critical for ophthalmologists, who are often the first to evaluate these patients. 2004-03-01T05:00:00Z XML http://www.modernmedicine.com/modernmedicine/Neurologic+Disorders/Helping-your-patients-through-Bells-palsy/ArticleStandard/Article/detail/108270?contextCategoryId=41155&ref=25 While not definitive, recent evidence suggests that early treatment with antiviral medications and corticosteroids may improve chances for full recovery from this sudden onset of facial paralysis. 2004-01-15T05:00:00Z HTML http://www.modernmedicine.com/modernmedicine/Feature+Articles/Considerations-for-the-treatment-of-multiple-scler/ArticleStandard/Article/detail/77805?contextCategoryId=41155&ref=25 The direct and indirect healthcare costs associated with multiple sclerosis are high. In the managed care setting, before treatment is initiated, these costs must be reconciled with other factors such as the epidemiological and clinical features of MS and current recommendations for pharmacologic management. Managed care organizations (MCOs) have the opportunity to improve the outcomes of MS through a system of care. MCOs can also manage the costs of the 2 first-line therapies (glatiramer and agents from the interferon class) used to treat MS by using stepped care and preferred formulary designations. In addition, improved outcomes can be achieved by establishing a disease management approach to treat MS. 2003-11-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/formulary/492003/77805/form1103_cover_thumbnail.jpg http://www.modernmedicine.com/modernmedicine/data/articlestandard/formulary/492003/77805/form1103_cover_main.jpg PDF http://www.modernmedicine.com/modernmedicine/Psychiatric+disorders/Meeting-the-challenge-of-suicide-prevention/ArticleStandard/Article/detail/111906?contextCategoryId=41155&ref=25 Recently recognized as a public health issue, suicide remains a major clinical challenge for primary care physicians, who are in a position to implement preventive measures. 2003-08-15T04:00:00Z HTML http://www.modernmedicine.com/modernmedicine/FDA+Approvals/Rebif-Interferon-beta-1a/ArticleStandard/Article/detail/16693?contextCategoryId=41155&ref=25 New biologic: Second interferon beta-1a product for relapsing multiple sclerosis 2002-04-01T05:00:00Z HTML