http://www.modernmedicine.com/modernmedicine/Alzheimer%27s+Disease/Article/list/40244 Are you looking for Alzheimer’s Disease news and information. Modern Medicine keeps you connected with medical articles and expert analysis. 2009-11-21T22:12:00Z http://www.modernmedicine.com/modernmedicine/Endocrinology/Rate-of-Cognitive-Decline-in-Alzheimers-Disease-Ev/ArticleNewsFeed/Article/detail/636875?contextCategoryId=40244&ref=25 In patients with diabetes mellitus and Alzheimer's disease, the presence of diabetes slows the rate of cognitive decline associated with Alzheimer's disease, according to a prospective, multi-center study in the Oct. 27 issue of Neurology. 2009-10-27T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/442009/636875/ALZHEIMER.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/442009/636875null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Cognitive-Factors-Preceding-Alzheimers-Disease-Exa/ArticleNewsFeed/Article/detail/634416?contextCategoryId=40244&ref=25 The onset of Alzheimer's disease can be seen on tests for several cognitive factors up to three years prior to clinical diagnosis, according to a study in the October issue of the Archives of Neurology. 2009-10-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/422009/634416/WHI088.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/422009/634416null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/CT-Scans-Found-Suitable-for-Use-in-Memory-Clinics/ArticleNewsFeed/Article/detail/631423?contextCategoryId=40244&ref=25 In patients attending a memory clinic, 64-detector row computed tomography yields findings that are almost as reliable as those from an MRI, according to a study published in the October issue of Radiology. 2009-10-05T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/412009/631423/BRAINsmall.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/412009/631423null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Breast-Cancer-Prevention-Drugs-and-Cognition-Studi/ArticleNewsFeed/Article/detail/628323?contextCategoryId=40244&ref=25 The selective estrogen receptor modulators tamoxifen and raloxifene, used for breast cancer prevention in postmenopausal women, have similar effects on cognition, according to a study published online Sept. 21 in the Journal of Clinical Oncology. 2009-09-22T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/392009/628323/46083.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/392009/628323null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Cognitive-Testing-Over-Phone-in-Person-Found-Simil/ArticleNewsFeed/Article/detail/627990?contextCategoryId=40244&ref=25 Conducting neuropsychological tests by telephone may provide similar results as tests administered in person for assessing cognition in older woman, according to research published online Aug. 20 in the International Journal of Geriatric Psychiatry. 2009-09-21T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/392009/627990/WHI088.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/392009/627990null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Dopamine-Important-for-Creating-Persistent-Memorie/ArticleNewsFeed/Article/detail/621052?contextCategoryId=40244&ref=25 The brain's dopamine system in the hippocampus is responsible for creating persistent long-term memory in rats, according to a study in the Aug. 21 issue of Science. 2009-08-24T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/352009/621052/brownrat.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/352009/621052null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Subclinical-Disease-Patterns-Studied-in-Cognitive-/ArticleNewsFeed/Article/detail/618180?contextCategoryId=40244&ref=25 White matter hyperintensity is strongly associated with amnestic mild cognitive impairment, while brain infarcts are more strongly associated with nonamnestic MCI in elderly individuals without dementia, according to a study in the Aug. 11 issue of Neurology. 2009-08-11T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/332009/618180/BRAINsmall.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/332009/618180null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Cause-of-Cognitive-Decline-After-Heart-Bypass-Exam/ArticleNewsFeed/Article/detail/617963?contextCategoryId=40244&ref=25 Use of a pump during coronary artery bypass surgery does not appear to be responsible for long-term loss of cognitive function and memory in patients with coronary artery disease; it instead may be due to the disease itself, according to a study in the August issue of the Annals of Thoracic Surgery. 2009-08-10T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/332009/617963/BRAIN.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/332009/617963null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/IVIg-treatment-associated-with-a-reduced-risk-of-A/ArticleStandard/Article/detail/616634?contextCategoryId=40244&ref=25 In a retrospective analysis published in the journal Neurology, investigators demonstrated that previous treatment with intravenous immunoglobulin (IVIg) was associated with a reduced risk of the development of Alzheimer's disease and related disorders (ADRD) in patients aged at least 65 years. 2009-08-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/formulary/322009/616634null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/ICAD-DHA-May-May-Not-Be-Helpful-in-Alzheimers-Dise/ArticleNewsFeed/Article/detail/610742?contextCategoryId=40244&ref=25 The jury is still out regarding the benefit of the omega-3 fatty acid docosahexaenoic acid in Alzheimer's disease, according to two double-blind multicenter clinical studies presented at the 2009 International Conference on Alzheimer's Disease, held from July 11 to 16 in Vienna, Austria. 2009-07-13T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/292009/610742/elderly_man.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/292009/610742null XML http://www.modernmedicine.com/modernmedicine/CME+Showcase/Screening-for-dementia/CME/Article/detail/608766?contextCategoryId=40244&ref=25 Screening for dementia 2009-07-03T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/cme/geriatrics/272009/608766null REMOTE http://www.modernmedicine.com/modernmedicine/CME+Showcase/Alzheimers-disease-summit-Translating-research-adv/CME/Article/detail/608765?contextCategoryId=40244&ref=25 The Alzheimer's Disease Summit, held on May 3, 2008, translated cutting-edge research into day-to-day practice. This supplement, based on information presented at the summit, presents valuable clinical content to a broad audience of primary care physicians, psychiatrists, geriatricians, and neurologists. 2009-07-03T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/cme/geriatrics/272009/608765null REMOTE http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Target-of-Inhibitors-of-Memory-Loss-Identified/ArticleNewsFeed/Article/detail/597446?contextCategoryId=40244&ref=25 One member of the histone deacetylase family, which represses gene expression, has been identified as a negative regulator of learning and memory and can be targeted by inhibitors leading to enhanced learning and memory, according to a study in the May 7 issue of Nature. 2009-05-08T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/192009/597446/elderly_puzzle.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/192009/597446null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Update-on-neuropsychiatric-symptoms-of-dementia-an/ArticleStandard/Article/detail/597269?contextCategoryId=40244&ref=25 Antipsychotic medications have a modest effect on the neuropsychiatric symptoms of dementia, but product labels warn of the excess risk of death and morbidity associated with their use in older patients. As such, these agents should not be the first choice for the treatment of behavioral and psychotic symptoms of dementia. Nevertheless, a trial of these agents may be indicated in instances in which the severity of symptoms is extreme, or symptoms do not respond to nonpharmacologic methods or other medications. 2009-05-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/geriatrics/192009/597269null XML http://www.modernmedicine.com/modernmedicine/CME+Showcase/Elderly-female-patient-presents-with-onset-of-resi/CME/Article/detail/641027?contextCategoryId=40244&ref=25 Elderly female patient presents with onset of resistant hypertension 2009-04-17T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/cme/geriatrics/462009/641027null REMOTE http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Hypoglycemic-Events-Increase-Dementia-Risk-with-Di/ArticleNewsFeed/Article/detail/593399?contextCategoryId=40244&ref=25 Incidents of hypoglycemia in older patients with type 2 diabetes increase the risk of their eventually developing dementia, according to a study reported in the April 15 issue of the Journal of the American Medical Association. 2009-04-14T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/162009/593399/elderly_man.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/162009/593399null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+News/News-flash-some-pediatricians-are-underpaid/ArticleStandard/Article/detail/591296?contextCategoryId=40244&ref=25 How much, if anything, does a pediatrician make when on call? 2009-04-02T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/contpeds/142009/591296null HTML http://geriatrics.modernmedicine.com/geriatrics/Modern+Medicine+Now/Update-on-neuropsychiatric-symptoms-of-dementia-ev/ArticleStandard/Article/detail/592048?contextCategoryId=40244&ref=25 With black box warnings on antipsychotics and doubts persisting about the efficacy and safety of other medications used off label, nonpharmacologic interventions in neuropsychiatric symptoms of dementia increase in importance. Behavioral management, cognitive stimulation therapy, and caregiver and health care staff education show the most promise. 2009-04-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/geriatrics/152009/592048null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Key-points-in-differential-diagnosis-of-dementia/ArticleStandard/Article/detail/585382?contextCategoryId=40244&ref=25 Degenerative dementia subtypes have more overlapping signs and symptoms than defining ones, but being able to distinguish among them is important because each has unique prognostic and treatment considerations. Key elements of the history, physical exam, and diagnostic tests can help reveal an accurate diagnosis. 2009-03-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/geriatrics/102009/585382null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/AAN-Brain-Exercise-May-Prevent-Cognitive-Impairmen/ArticleNewsFeed/Article/detail/582351?contextCategoryId=40244&ref=25 In middle and older age, reading and other mentally stimulating activities may help prevent mild cognitive impairment, according to research that will be presented April 25-May 2 at the American Academy of Neurology's 61st Annual Meeting in Seattle. 2009-02-18T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/082009/582351/seniors_40097.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/082009/582351null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Non-pharmacologic-treatment-of-insomnia-in-persons/ArticleStandard/Article/detail/580284?contextCategoryId=40244&ref=25 Insomnia affects up to 35% of community-dwelling adults with dementia. Although non-pharmacologic treatments can be safe and effective alternatives to the sedative-hypnotic medications commonly prescribed, practical approaches such as light therapy, exercise, and sleep-hygiene modification are often underused in clinical practice to treat insomnia in patients with dementia. 2009-02-15T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/geriatrics/062009/580284null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Anticholinergic-Agents-Linked-to-Cognitive-Impairm/ArticleNewsFeed/Article/detail/578636?contextCategoryId=40244&ref=25 Cumulative long-term use of anticholinergic medications can lead to cognitive impairment, including poor memory and executive function, according to study findings published in the December issue of the Journal of the American Geriatrics Society. 2009-01-30T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/052009/578636/seniors_40121.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/052009/578636null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Some-Alcohol-May-Preserve-Cognition-in-Older-Women/ArticleNewsFeed/Article/detail/573289?contextCategoryId=40244&ref=25 Older women who drink low or moderate amounts of alcohol may have better cognitive performance and a slower rate of cognitive decline compared to those who don't drink, according to research published in the December issue of the Journal of the American Geriatrics Society. 2008-12-29T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/012008/573289/nlf016.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/012008/573289null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Imaging-Reveals-Age-Related-Memory-Differences/ArticleNewsFeed/Article/detail/572514?contextCategoryId=40244&ref=25 Activity in the amygdala linked to subsequent memory of negative images was preserved in older adults, but older individuals had less subsequent-memory activity for negative pictures in visual cortices, according to research published in the January issue of Psychological Science. 2008-12-19T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/512008/572514/BRAIN.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/512008/572514null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/RSNA-Brain-Abnormalities-Seen-in-Psychiatric-Disor/ArticleNewsFeed/Article/detail/569436?contextCategoryId=40244&ref=25 Patients with stress-related psychiatric disorders may have dysfunctional circuitry in the area of the brain responsible for suppressing memory, according to research presented at the annual meeting of the Radiological Society of North America held Nov. 30 to Dec. 5 in Chicago. 2008-12-03T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/492008/569436/BRAIN.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/492008/569436null XML http://www.modernmedicine.com/modernmedicine/CME+Showcase/The-Conundrum-of-Sleep-and-Neurodegenerative-Disea/CME/Article/detail/640951?contextCategoryId=40244&ref=25 Primary and comorbid insomnia are more common than most physicians think, as 1 in 10 Americans has chronic insomnia. 2008-12-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/cme/geriatrics/462009/640951null REMOTE http://www.modernmedicine.com/modernmedicine/Treatment+Areas/Razadyne-generic-wins-FDA-approval/ArticleStandard/Article/detail/562967?contextCategoryId=40244&ref=25 Barr Pharmaceuticals has received final FDA approval for galantamine, its generic version of Ortho McNeil Janssen's Razadyne ER, for the treatment of mild to moderate dementia of the Alzheimer's type. 2008-11-10T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/drugtopics/452008/562967null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Vitamin-B-Improves-Brain-Function-in-Alzheimers/ArticleNewsFeed/Article/detail/564069?contextCategoryId=40244&ref=25 High doses of a form of vitamin B improve cognition and reverse some of the pathological changes associated with Alzheimer's disease in a mouse model of the disease, according to a report in the Nov. 5 issue of the Journal of Neuroscience. 2008-11-06T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/452008/564069/ALZHEIMER.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/452008/564069null XML http://www.modernmedicine.com/modernmedicine/clinical+insights/Study-confirms-benefit-of-2-drug-therapy-for-Alzhe/ArticleStandard/Article/detail/552572?contextCategoryId=40244&ref=25 Extended treatment with Alzheimer's disease drugs can significantly slow the rate at which the disorder advances, and combination therapy with 2 different classes of drugs is even better at helping patients maintain their ability to perform daily activities. Results from the first long-term study of the real-world use of Alzheimer?s drugs were published by researchers from Massachusetts General Hospital in the July/September issue of Alzheimer Disease and Associated Disorders. 2008-09-24T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/geriatrics/392008/552572null HTML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/ASTRO-Whole-Brain-Radiation-Linked-to-Cognitive-De/ArticleNewsFeed/Article/detail/552394?contextCategoryId=40244&ref=25 The risk of neurocognitive decline is twice as high among cancer patients with brain metastases who undergo stereotactic radiosurgery and whole brain radiation than in those who undergo stereotactic radiosurgery alone. Also, the risk of severe psychological distress is significantly increased in long-term survivors of adult-onset cancer, according to research presented at the American Society for Therapeutic Radiology and Oncology's 50th Annual Meeting held Sept. 21 to 25 in Boston. 2008-09-23T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/392008/552394/BRAIN.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/392008/552394null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Exercise-Improves-Cognition-in-At-Risk-Older-Adult/ArticleNewsFeed/Article/detail/547302?contextCategoryId=40244&ref=25 In older adults with subjective memory impairment, a six-month program of physical activity may lead to modest improvements in cognition, suggesting that exercise may help prevent Alzheimer's disease, according to research published in the Sept. 3 issue of the Journal of the American Medical Association. 2008-09-02T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/362008/547302/elderlyexercise_59329.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/362008/547302null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Gene-Affects-Many-Behavioral-and-Cognitive-Domains/ArticleNewsFeed/Article/detail/546512?contextCategoryId=40244&ref=25 The COMT (catechol-O-methyltransferase) gene may play an important role in a trade-off between cognitive and affective function with increased COMT activity inhibiting cognition, but functioning as a protective factor in stressful situations, according to an article published in the Aug. 27 issue of the Journal of Neuroscience. 2008-08-29T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/352008/546512/dna20.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/352008/546512null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Structure-of-Mutant-Tau-Protein-Altered-in-Alzheim/ArticleNewsFeed/Article/detail/543993?contextCategoryId=40244&ref=25 A mutant form of the tau protein, which forms intracellular aggregates in the brains of patients with Alzheimer's disease, may aggregate due to sequence-specific structural changes in the protein that cause it to adopt a more extended conformation, according to study findings published online Aug. 22 in PLoS Computational Biology. 2008-08-22T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/342008/543993/alzheimers.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/342008/543993null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Independence-Declines-Modestly-at-Advanced-Ages/ArticleNewsFeed/Article/detail/543572?contextCategoryId=40244&ref=25 Among the oldest elderly, the numbers of those who remain independent declines only modestly in their 90s by one measure, according to research published online Aug. 18 in the Proceedings of the National Academy of Sciences Early Edition. 2008-08-20T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/342008/543572/33271.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/342008/543572null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Scan-Could-Prove-Useful-in-Diagnosing-Alzheimers/ArticleNewsFeed/Article/detail/542372?contextCategoryId=40244&ref=25 The use of carbon 11-labeled Pittsburgh Compound B positron emission tomography ([11C]PiB PET) may be useful in assessing β-amyloid deposition in the brain, according to research published online Aug. 11 in the Archives of Neurology. 2008-08-14T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/332008/542372/BRAIN.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/332008/542372null XML http://www.modernmedicine.com/modernmedicine/Pathology/Physical-Frailty-Linked-to-Alzheimers-Brain-Pathol/ArticleNewsFeed/Article/detail/542181?contextCategoryId=40244&ref=25 Physical frailty in the elderly is associated with Alzheimer's disease pathology in the brain independent of dementia and other potential variables, researchers report in the Aug. 12 issue of Neurology. 2008-08-13T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/332008/542181/elderly_59328.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/332008/542181null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Cognitive-Problems-Linked-to-Longer-More-Severe-Di/ArticleNewsFeed/Article/detail/535379?contextCategoryId=40244&ref=25 Mild cognitive impairment is associated with earlier onset, longer duration and greater severity of diabetes mellitus, according to research published in the August issue of the Archives of Neurology. 2008-08-12T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/332008/535379/WHI088.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/332008/535379null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/International-Conference-on-Alzheimers-Disease-Jul/ArticleNewsFeed/Article/detail/533768?contextCategoryId=40244&ref=25 2008-08-04T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/322008/533768null XML http://www.modernmedicine.com/modernmedicine/General+Ophthalmology+Feature/Increase-of-receptor-for-advanced-glycation-end-pr/ArticleStandard/Article/detail/533937?contextCategoryId=40244&ref=25 Immunohistochemical studies have shown that the receptor for advanced glycation end products (RAGE) is elevated in the optic nerves of patients with Alzheimer's disease. Future studies are expected to provide more information about the role of RAGE in Alzheimer's disease and other neurodegenerative diseases and could lead to new therapeutic options if RAGE is determined to be a causative agent. 2008-08-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/ophthalmologytimes/322008/533937null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/ICAD-Genetic-Lifestyle-Factors-Linked-to-Alzheimer/ArticleNewsFeed/Article/detail/532840?contextCategoryId=40244&ref=25 Novel risk factors for Alzheimer's disease may include a maternal history of the disease and living alone at midlife, according to research presented this week at the Alzheimer's Association's International Conference on Alzheimer's Disease in Chicago. 2008-07-30T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/312008/532840/3generations.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/312008/532840null XML http://www.modernmedicine.com/modernmedicine/Pathology/ICAD-New-Drugs-May-Benefit-Alzheimers-Patients/ArticleNewsFeed/Article/detail/532843?contextCategoryId=40244&ref=25 Three novel agents show promise in the treatment of Alzheimer's disease, according to research presented this week at the Alzheimer's Association's International Conference on Alzheimer's Disease in Chicago. 2008-07-30T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/312008/532843/alzheimers.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/312008/532843null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/ICAD-Dont-Treat-Alzheimers-Patients-Like-Children/ArticleNewsFeed/Article/detail/532609?contextCategoryId=40244&ref=25 During conversations with Alzheimer's patients, respectful adult communication results in more cooperation and higher quality of care, according to research presented at the International Conference on Alzheimer's Disease, held July 26-31 in Chicago. 2008-07-29T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/312008/532609/elderly_59322.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/312008/532609null XML http://www.modernmedicine.com/modernmedicine/Pathology/ICAD-Biomarkers-Linked-to-Early-Alzheimers-Disease/ArticleNewsFeed/Article/detail/532607?contextCategoryId=40244&ref=25 Biomarkers in blood and spinal fluid may help identify early Alzheimer's disease, according to research presented this week at the 2008 Alzheimer's Association International Conference on Alzheimer's Disease in Chicago. 2008-07-29T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/312008/532607/blood_18089.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/312008/532607null XML http://www.modernmedicine.com/modernmedicine/Pathology/ICAD-Alzheimers-Studies-Show-Mixed-Results/ArticleNewsFeed/Article/detail/532606?contextCategoryId=40244&ref=25 Despite a phase 3 study showing that the anti-amyloid drug tarenflurbil is ineffective against Alzheimer's disease, studies of other agents show possible benefit, according to research presented this week at the 2008 Alzheimer's Association International Conference on Alzheimer's Disease in Chicago and published in The Lancet Neurology. 2008-07-29T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/312008/532606/alzheimers2.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/312008/532606null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Statin-Use-May-Decrease-Cognitive-Impairment/ArticleNewsFeed/Article/detail/532461?contextCategoryId=40244&ref=25 Statin use is associated with a significant decline in dementia and other cognitive impairment, according to the July 29 issue of Neurology. 2008-07-29T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/312008/532461/ekg_MIC069ML.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/312008/532461null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Dementia-Rate-May-Be-Underestimated-in-Some-Areas/ArticleNewsFeed/Article/detail/532063?contextCategoryId=40244&ref=25 Usage of the DSM-IV may markedly underestimate the prevalence of dementia in less developed areas of the world, according to research published online July 28 in The Lancet. 2008-07-28T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/312008/532063/seniors_40121.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/312008/532063null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/ICAD-New-Technology-Can-Detect-Early-Alzheimers/ArticleNewsFeed/Article/detail/532064?contextCategoryId=40244&ref=25 New magnetic resonance imaging (MRI) technology shows promise in the early detection of Alzheimer's disease, according to research presented at the International Conference on Alzheimer's Disease, held July 26-31 in Chicago. 2008-07-28T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/312008/532064/BRAIN.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/312008/532064null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Cognitive-Function-Poorer-with-Coronary-Heart-Dise/ArticleNewsFeed/Article/detail/531623?contextCategoryId=40244&ref=25 Coronary heart disease is associated with poor cognitive performance in middle age, with greater declines in cognitive function among men with increased time since first coronary event, according to an article published online July 22 in the European Heart Journal. 2008-07-24T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/302008/531623/fac071.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/302008/531623null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Memory-and-Central-Auditory-Function-Related/ArticleNewsFeed/Article/detail/531379?contextCategoryId=40244&ref=25 A stepwise decline in central auditory function was noted when comparing patients with mild memory impairment and no dementia to Alzheimer's patients with memory loss, according to an article published in the July issue of the Archives of Otolaryngology -- Head & Neck Surgery. 2008-07-23T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/302008/531379/ear_SS36021.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/302008/531379null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Dimebon-Improves-Cognition-in-Alzheimers-Patients/ArticleNewsFeed/Article/detail/530773?contextCategoryId=40244&ref=25 Dimebon improved the clinical course of patients with mild-to-moderate Alzheimer's disease and was both safe and well tolerated, according to the results of a study published in the July 19 issue of The Lancet. 2008-07-18T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/292008/530773/seniorspuzzle_40115.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/292008/530773null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Revised-Mental-Exam-Cut-Score-May-Benefit-Well-Edu/ArticleNewsFeed/Article/detail/529951?contextCategoryId=40244&ref=25 A cut score of 27 on the Mini-Mental State Examination (MMSE) may be more useful in identifying dementia in older patients with a college education than the traditional cut score of 24, according to research published in the July issue of the Archives of Neurology. 2008-07-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/292008/529951/elderly_puzzle.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/292008/529951null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Fitness-May-Reduce-Brain-Atrophy-in-Alzheimers-Dis/ArticleNewsFeed/Article/detail/529840?contextCategoryId=40244&ref=25 In patients with early Alzheimer's disease, increased cardiorespiratory fitness is associated with reduced brain atrophy, but the reasons are unclear, according to a study published in the July 15 issue of Neurology. 2008-07-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/292008/529840/man_walking_33011.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/292008/529840null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Dietary-Cocktail-Improves-Memory-in-Animal-Study/ArticleNewsFeed/Article/detail/529499?contextCategoryId=40244&ref=25 A dietary cocktail containing an omega-3 fatty acid significantly improves memory and learning in gerbils, suggesting that a similar cocktail may benefit patients with Alzheimer's disease and other forms of dementia, according to a report published online July 7 in the FASEB Journal: The Journal of the Federation of American Societies of Experimental Biology. 2008-07-14T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/292008/529499/BRAINsmall.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/292008/529499null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Abnormal-Scan-Predicts-Poor-Prognosis-in-Mild-Brai/ArticleNewsFeed/Article/detail/529258?contextCategoryId=40244&ref=25 Children with normal computed tomography (CT) findings perform better in multiple cognitive domains one year after mild traumatic brain injury than children with CT evidence of intracranial pathology, according to an article published in the June issue of the Journal of Neurosurgery: Pediatrics. 2008-07-11T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/282008/529258/scan_18039.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/282008/529258null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Apolipoprotein-E-Genotype-Cortisol-Linked-to-Cogni/ArticleNewsFeed/Article/detail/529057?contextCategoryId=40244&ref=25 APOE-ε4 genotype may play a role in an individual's susceptibility to the consequences of hypothalamic-pituitary-adrenal axis dysregulation on cognitive function, researchers report in a study published online July 1 in the American Journal of Psychiatry. 2008-07-10T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/282008/529057/BRAIN.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/282008/529057null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Hypertension-Treatment-Beneficial-in-Very-Elderly/ArticleNewsFeed/Article/detail/528320?contextCategoryId=40244&ref=25 Treatment of very elderly patients for high blood pressure may slightly lower the risk of dementia but is clearly beneficial in reducing strokes and mortality, according to research published online July 8 in The Lancet Neurology. 2008-07-08T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/282008/528320/33107.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/282008/528320null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Questionnaire-Evaluates-Everyday-Cognition-in-Elde/ArticleNewsFeed/Article/detail/527603?contextCategoryId=40244&ref=25 A caregiver-rated questionnaire to evaluate everyday cognitive function in the elderly is effective and can differentiate between cognitively normal and impaired individuals, according to a report in the July issue of Neuropsychology. 2008-07-02T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/272008/527603/seniors_40098.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/272008/527603null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Cholesterol-Level-Linked-to-Poor-Memory-in-Middle-/ArticleNewsFeed/Article/detail/527498?contextCategoryId=40244&ref=25 Middle-aged individuals with low high-density lipoprotein cholesterol (HDL-C) levels are at higher risk of poor memory and memory decline than individuals with high levels of HDL-C, according to the results of a study published online June 30 in Arteriosclerosis, Thrombosis, and Vascular Biology. 2008-07-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/272008/527498/271201a.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/272008/527498null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Error-in-iCALHM1i-Gene-Linked-to-Alzheimers-Diseas/ArticleNewsFeed/Article/detail/526523?contextCategoryId=40244&ref=25 A single-nucleotide polymorphism in the gene CALHM1, found on chromosome 10, may increase the risk of late-onset Alzheimer's disease, researchers report in the June 27 issue of Cell. 2008-06-27T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/262008/526523/GENETICS.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/262008/526523null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Automated-Imaging-Method-Identifies-Alzheimers-Pat/ArticleNewsFeed/Article/detail/525803?contextCategoryId=40244&ref=25 An automated method to measure hippocampal volume can accurately distinguish between patients with Alzheimer's disease, mild cognitive impairment or healthy elderly patients, according to research published in the July issue of Radiology. 2008-06-24T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/262008/525803/alzheimers.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/262008/525803null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Apnea-Linked-to-Lower-Mammillary-Body-Volume/ArticleNewsFeed/Article/detail/525063?contextCategoryId=40244&ref=25 Patients with obstructive sleep apnea showed lower mammillary body volumes compared to control subjects, which may be a factor in the memory deficits known to accompany the condition, according to research published in the June 27 Neuroscience Letters. 2008-06-19T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/252008/525063/BRAIN.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/252008/525063null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Drugs-Modulate-Protein-Important-in-Alzheimers/ArticleNewsFeed/Article/detail/524889?contextCategoryId=40244&ref=25 Some non-steroidal anti-inflammatory drugs can bind to the amyloid-β protein, affecting the production of a pathogenic peptide and inhibiting its aggregation, which may be useful in reducing the deposition of amyloid-β in patients with Alzheimer's disease, researchers report in the June 12 issue of Nature. 2008-06-18T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/252008/524889/33271.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/252008/524889null XML http://www.modernmedicine.com/modernmedicine/Managed+Care/FDA-Issues-Safety-Warning-for-Older-Antipsychotic-/ArticleNewsFeed/Article/detail/524489?contextCategoryId=40244&ref=25 Labels for older or so-called "conventional" antipsychotic drugs will have to carry boxed warnings of increased risk of death among elderly dementia patients who take the drugs off-label for behavioral problems, similar to warnings already required for newer or "atypical" antipsychotic drugs, the U.S. Food and Drug Administration announced June 16. 2008-06-17T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/272009/524489/pillbottle_59037.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/272009/524489null XML http://www.modernmedicine.com/modernmedicine/Geriatrics/Middle-Aged-Smokers-at-Risk-of-Memory-Loss/ArticleNewsFeed/Article/detail/523304?contextCategoryId=40244&ref=25 Middle-aged smokers are at greater risk of poor memory, but studying the impact of smoking on cognition is hampered by the greater rate of loss to follow-up by death and non-participation in tests compared to non-smokers, according to study findings published in the June 9 issue of the Archives of Internal Medicine. 2008-06-11T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/242008/523304/smoking_40220.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/242008/523304null XML http://www.modernmedicine.com/modernmedicine/Neurology/Aging-Issues-Linked-to-Interpersonal-Relationships/ArticleNewsFeed/Article/detail/520170?contextCategoryId=40244&ref=25 Factors related to declines in later life, namely the role of social integration in memory function and the risk of entering long-term institutional care following the death of a spouse, are assessed in two new studies published online May 29 in the American Journal of Public Health. 2008-05-30T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/222008/520170/WHI087.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/222008/520170null XML http://www.modernmedicine.com/modernmedicine/Neurology/Class-of-Drugs-Protective-Against-Alzheimers/ArticleNewsFeed/Article/detail/519992?contextCategoryId=40244&ref=25 All types of non-steroidal anti-inflammatory drugs (NSAIDs), including aspirin, have a similarly protective effect against Alzheimer's dementia, and there is not particular benefit to using the selective Aβ42-lowering subset of NSAIDs, according to research published in the June 10 issue of Neurology. 2008-05-29T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/222008/519992/drugs_MIC065ML.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/222008/519992null XML http://www.modernmedicine.com/modernmedicine/Neurology/Non-Steroidals-Protective-Against-Alzheimers-Disea/ArticleNewsFeed/Article/detail/514978?contextCategoryId=40244&ref=25 Long-term use of non-steroidal anti-inflammatory drugs (NSAIDs) appears to protect against the development of Alzheimer's disease, according to an article published in the May 6 issue of Neurology. 2008-05-06T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/192008/514978/alzheimers.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/192008/514978null XML http://www.modernmedicine.com/modernmedicine/Neurology/Tarenflurbil-Shows-Some-Promise-in-Mild-Alzheimers/ArticleNewsFeed/Article/detail/513985?contextCategoryId=40244&ref=25 In patients with mild Alzheimer's disease, the selective Aβ42-lowering agent tarenflurbil may slow declines in activities of daily living and global function, according to the results of a phase II trial published online April 30 in The Lancet Neurology. 2008-05-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/182008/513985/WHI088.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/182008/513985null XML http://www.modernmedicine.com/modernmedicine/Neurology/Tethered-Inhibitor-More-Effective-for-Alzheimers/ArticleNewsFeed/Article/detail/512528?contextCategoryId=40244&ref=25 An inhibitor of an Alzheimer's disease target that is tethered to the cell membrane is more effective than the free inhibitor, and the approach could be used to design more effective inhibitors, according to a study in the April 25 issue of Science. 2008-04-25T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/172008/512528/alzheimsmall.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/172008/512528null XML http://www.modernmedicine.com/modernmedicine/Neurology/Triglycerides-May-Explain-Cognition-Problems-in-Ob/ArticleNewsFeed/Article/detail/512530?contextCategoryId=40244&ref=25 Experiments with mice suggest that triglycerides play a major role in obesity-related cognitive disturbance and that lowering triglycerides can improve such impairment, according to research published in the May issue of Endocrinology. 2008-04-25T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/172008/512530/mouse.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/172008/512530null XML http://www.modernmedicine.com/modernmedicine/Neurology/Protein-State-Affects-Behavior-of-Alzheimers-Prote/ArticleNewsFeed/Article/detail/512213?contextCategoryId=40244&ref=25 In neurodegenerative diseases such as Alzheimer's disease that involve abnormalities in the tau protein (tauopathies), a tau-regulating protein has opposite effects on tauopathy in mice depending on whether the tau is normal or mutant, according to a study published online April 22 in The Journal of Clinical Investigation. 2008-04-24T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/172008/512213/alzheimsmall.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/172008/512213null XML http://www.modernmedicine.com/modernmedicine/Neurology/AAN-Medications-Linked-to-Cognitive-Decline/ArticleNewsFeed/Article/detail/510961?contextCategoryId=40244&ref=25 Older adults who start taking medications with anticholinergic activity may have an increased risk of cognitive impairment, according to research presented this week at the annual meeting of the American Academy of Neurology in Chicago. 2008-04-18T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/162008/510961/WHI088.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/162008/510961null XML http://www.modernmedicine.com/modernmedicine/Neurology/AAN-Vitamin-E-May-Improve-Survival-in-Alzheimers/ArticleNewsFeed/Article/detail/510415?contextCategoryId=40244&ref=25 In patients with Alzheimer's disease, treatment regimens that include high doses of vitamin E are associated with significantly improved survival, according to research presented this week at the annual meeting of the American Academy of Neurology in Chicago. 2008-04-16T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/162008/510415/vitamin_e.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/162008/510415null XML http://www.modernmedicine.com/modernmedicine/Neurology/AAN-Cholesterol-Lifestyle-Linked-to-Alzheimers-Dis/ArticleNewsFeed/Article/detail/510519?contextCategoryId=40244&ref=25 Patients with elevated cholesterol levels in midlife are at increased risk of developing Alzheimer's disease, and patients with a history of consuming more than two alcoholic beverages per day or smoking more than one pack of cigarettes per day are at increased risk of developing earlier Alzheimer's disease, according to two studies presented this week at the annual meeting of the American Academy of Neurology in Chicago. 2008-04-16T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/162008/510519/alzheimers.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/162008/510519null XML http://www.modernmedicine.com/modernmedicine/Neurology/AAN-Causes-of-Young-Onset-Dementia-Identified/ArticleNewsFeed/Article/detail/510336?contextCategoryId=40244&ref=25 Dementia onset is not uncommon among patients under age 45, and its most frequent causes are neurodegenerative and autoimmune/inflammatory conditions. Only rarely is Alzheimer's disease responsible for young-onset dementia, according to research presented this week at the annual meeting of the American Academy of Neurology in Chicago. 2008-04-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/162008/510336/BRAIN.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/162008/510336null XML http://www.modernmedicine.com/modernmedicine/Neurology/Impaired-Insulin-Secretion-Increases-Alzheimers-Ri/ArticleNewsFeed/Article/detail/509415?contextCategoryId=40244&ref=25 An impaired insulin response at 50 years of age is associated with an increased risk of developing Alzheimer's disease, according to research published online April 9 in Neurology. 2008-04-10T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/152008/509415/alzheimers.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/152008/509415null XML http://www.modernmedicine.com/modernmedicine/Neurology/Depressive-Symptoms-Not-Linked-to-Alzheimers-Risk/ArticleNewsFeed/Article/detail/508514?contextCategoryId=40244&ref=25 Elderly individuals with depressive symptoms or with no increase in depressive symptoms do not have an increased risk of developing Alzheimer's disease, although those with a history of depression are at increased risk, researchers report in two studies published in the Archives of General Psychiatry and Neurology in April. 2008-04-08T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/152008/508514/seniors_40121.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/152008/508514null XML http://www.modernmedicine.com/modernmedicine/Neurology/Caffeine-May-Protect-Blood-Brain-Barrier-in-Alzhei/ArticleNewsFeed/Article/detail/508269?contextCategoryId=40244&ref=25 Chronic caffeine ingestion appears to protect against disruptions in the blood brain barrier caused by a cholesterol-enriched diet in rabbits, suggesting that caffeine might be useful in Alzheimer's disease and other disorders characterized by breakdown of the blood brain barrier, according to research published April 3 in the Journal of Neuroinflammation. 2008-04-07T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/152008/508269/48022small.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/152008/508269null XML http://www.modernmedicine.com/modernmedicine/Neurology/Cellular-Pathway-Implicated-in-Alzheimers-Disease/ArticleNewsFeed/Article/detail/504606?contextCategoryId=40244&ref=25 A cellular signaling pathway is involved in increased production of amyloid-beta (Aβ) in mice and could be targeted in Alzheimer's disease, researchers report in the March 13 issue of Neuron. 2008-03-21T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/122008/504606/alzheimers.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/122008/504606null XML http://www.modernmedicine.com/modernmedicine/GERIATRICS/Research-Briefs-Geriatrics/ArticleStandard/Article/detail/499690?contextCategoryId=40244&ref=25 Vitamin D supplementation plus Ca may reduce risk of falls in elderly women in sunny climes; No link found between statin use and Alzheimer's disease; Low testosterone levels linked to increased risk of bone fractures in older men for up to 13 years; Estimates given for survival after onset of dementia; Statins reduce mortality risk in elderly CHD patients 2008-03-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/geriatrics/102008/499690null XML http://www.modernmedicine.com/modernmedicine/Neurology/Two-Parents-with-Alzheimers-Raises-Risk-for-Offspr/ArticleNewsFeed/Article/detail/502105?contextCategoryId=40244&ref=25 The children of parents who both have Alzheimer's disease are at increased risk of developing the disease themselves, relative to the general population, but the exact genetic mechanism for this is not yet understood, according to study findings published in the March issue of the Archives of Neurology. 2008-03-11T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/112008/502105/alzheimers2.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/112008/502105null XML http://www.modernmedicine.com/modernmedicine/Neurology/Donepezil-Reduces-Sleep-Apnea-in-Alzheimers/ArticleNewsFeed/Article/detail/500199?contextCategoryId=40244&ref=25 In patients with mild-to-moderate Alzheimer's disease, treatment with donepezil may reduce symptoms of obstructive sleep apnea, according to the results of a small study published in the March issue of the journal Chest 2008-03-04T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/102008/500199/oldsleeper.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/102008/500199null XML http://www.modernmedicine.com/modernmedicine/Alzheimer%27s+Disease/Letter-Of-Estrogen-Alzheimers-and-Male-and-Female-/ArticleStandard/Article/detail/541861?contextCategoryId=40244&ref=25 I have read both that the male brain has no estrogen receptors and that testosterone is converted to estrogen in the brain. Where does the truth lie? And what role, if any, does estrogen play in preventing Alzheimer disease in both men and women? 2008-03-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/332008/541861null XML http://www.modernmedicine.com/modernmedicine/Neurology/More-Data-Needed-on-Ginkgo-Bilobas-Effect-on-Memor/ArticleNewsFeed/Article/detail/498935?contextCategoryId=40244&ref=25 In a recent randomized controlled trial, ginkgo biloba did not appear to protect against age-related cognitive decline in elderly individuals. However, a secondary analysis that took into account patients' adherence with the medication did suggest a neuroprotective effect, according to an article published online Feb. 27 in Neurology. 2008-02-28T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092008/498935/gingko.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092008/498935null XML http://www.modernmedicine.com/modernmedicine/Endocrinology/Brain-Insulin-Affects-Memory-Function-in-Women/ArticleNewsFeed/Article/detail/494576?contextCategoryId=40244&ref=25 New research suggests that insulin has differential effects in the brains of men and women, and that in women in particular, insulin affects memory function, according to study findings released online Jan. 29 in advance of publication in the Journal of Clinical Endocrinology and Metabolism. 2008-02-26T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092008/494576/nasalspray_40028.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092008/494576null XML http://www.modernmedicine.com/modernmedicine/Endocrinology/Brain-Insulin-Affects-Memory-Function-in-Women/ArticleNewsFeed/Article/detail/494577?contextCategoryId=40244&ref=25 New research suggests that insulin has differential effects in the brains of men and women, and that in women in particular, insulin affects memory function, according to study findings released online Jan. 29 in advance of publication in the Journal of Clinical Endocrinology and Metabolism. 2008-02-26T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092008/494577/nasalspray_40028.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092008/494577null XML http://www.modernmedicine.com/modernmedicine/Cardiology/Listening-to-Music-Can-Improve-Recovery-After-Stro/ArticleNewsFeed/Article/detail/494377?contextCategoryId=40244&ref=25 Patients who listened to music regularly during the early stages of recovery after a stroke had better improvements in verbal memory and focused attention than patients who listened to audio books or those in a control group, according to the results of a study published online Feb. 20 in the journal Brain. 2008-02-25T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092008/494377/music.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092008/494377null XML http://www.modernmedicine.com/modernmedicine/Geriatrics/Alzheimers-disease/CustomizableHandout/Article/detail/554808?contextCategoryId=40244&ref=25 Alzheimer's disease (AD), one form of dementia, is a progressive, degenerative brain disease. It affects memory, thinking, and behavior. 2008-02-13T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/customizablehandout/modernmedicine/402008/554808null XML http://www.modernmedicine.com/modernmedicine/Neurology/Antioxidants-Dont-Prevent-Dementia-or-Alzheimers/ArticleNewsFeed/Article/detail/489983?contextCategoryId=40244&ref=25 In older adults, the use of supplemental vitamins E and C, alone or in combination, does not protect against dementia or Alzheimer's disease, according to study findings published in the February issue of the Journal of the American Geriatrics Society. 2008-02-07T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/062008/489983/alzheimers2.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/062008/489983null XML http://www.modernmedicine.com/modernmedicine/Neurology/Possible-Alzheimers-Disease-Therapy-Falters-in-Lab/ArticleNewsFeed/Article/detail/488056?contextCategoryId=40244&ref=25 New findings on the behavior of amyloid inhibitors -- considered possible therapeutic candidates for diseases such as Alzheimer's and Huntington's -- cast doubt on their usefulness. The research was published online Jan. 27 in the journal Nature Chemical Biology. 2008-01-30T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/052008/488056/microscope_mic034ml.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/052008/488056null XML http://www.modernmedicine.com/modernmedicine/Geriatrics/No-Link-Found-Between-Statin-Use-and-Alzheimers-Di/ArticleNewsFeed/Article/detail/485340?contextCategoryId=40244&ref=25 There appears to be no relationship between the use of statins and Alzheimer's disease or neuropathologies associated with Alzheimer's, according to a report published online Jan. 16 in Neurology. 2008-01-17T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/032008/485340/WHI088.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/032008/485340null XML http://www.modernmedicine.com/modernmedicine/Geriatrics/Reduced-Alzheimers-Risk-with-NSAIDs-Depends-on-Gen/ArticleNewsFeed/Article/detail/481418?contextCategoryId=40244&ref=25 Elderly individuals who take non-steroidal anti-inflammatory drugs (NSAIDs) have a lower risk of developing dementia and Alzheimer's disease, although the reduction for Alzheimer's is found only in individuals with a particular genetic background, researchers report in the Jan. 1 issue of Neurology. 2007-12-31T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/012007/481418/pills_MIC067ML.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/012007/481418null XML http://www.modernmedicine.com/modernmedicine/Neurology/Sugary-Beverages-May-Promote-Alzheimers-Disease/ArticleNewsFeed/Article/detail/478851?contextCategoryId=40244&ref=25 Sugar-sweetened beverages can worsen memory and promote the development of plaques in a mouse model of Alzheimer's disease, researchers report in the Dec. 14 issue of the Journal of Biological Chemistry. 2007-12-12T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/502007/478851/coke.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/502007/478851null XML http://www.modernmedicine.com/modernmedicine/Neurology/Progesterone-Estrogen-Show-Promise-in-Alzheimers-S/ArticleNewsFeed/Article/detail/476407?contextCategoryId=40244&ref=25 Estrogen and progesterone, taken together or separately, may cut the risk of Alzheimer's disease in postmenopausal women, according to the results of a study in mice published in the Nov. 28 issue of the Journal of Neuroscience. 2007-11-29T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/482007/476407/mouse.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/482007/476407null XML http://www.modernmedicine.com/modernmedicine/Neurology/Search-for-Alzheimers-Genetic-Link-Finds-Candidate/ArticleNewsFeed/Article/detail/473758?contextCategoryId=40244&ref=25 A genomewide association analysis found that the APOE linkage disequilibrium region was the strongest genetic risk factor for Alzheimer's disease, although others warrant further investigation. The research was published online Nov. 12 in the Archives of Neurology. 2007-11-19T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/472007/473758/BRAIN.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/472007/473758null XML http://www.modernmedicine.com/modernmedicine/Neurology/Race-and-Ethnicity-Impact-Survival-in-Alzheimers-D/ArticleNewsFeed/Article/detail/473197?contextCategoryId=40244&ref=25 African American and Latino patients appear to survive longer than white patients following a diagnosis of Alzheimer's disease, according to research published online Nov. 14 in Neurology. 2007-11-15T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/462007/473197/elderly_59335.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/462007/473197null XML http://www.modernmedicine.com/modernmedicine/Alzheimer%27s+Disease/Recognizing-apathy-in-Alzheimers-disease/ArticleStandard/Article/detail/469695?contextCategoryId=40244&ref=25 Apathy has been increasingly recognized as a neuropsychiatric symptom in many neurologic disorders. Since apathy per se almost never occurs as an isolated syndrome, it must be viewed in the context of an individual's entire behavioral and cognitive status. 2007-11-15T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/geriatrics/442007/469695null XML http://www.modernmedicine.com/modernmedicine/GERIATRICS/NEWS-amp-VIEWS/ArticleStandard/Article/detail/469684?contextCategoryId=40244&ref=25 Elevated BMI may not impair cognitive function; No evidence that assisted dying imposed on the older old; Mediterranean diet may slow advancement of AD 2007-11-15T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/geriatrics/442007/469684null XML http://www.modernmedicine.com/modernmedicine/Alzheimer%27s+Disease/Dementia-workup-and-treatment-Do-the-drugs-really-/ArticleStandard/Article/detail/471142?contextCategoryId=40244&ref=25 Early diagnosis is the first best possible step in the long-term management of Alzheimer's disease. It allows for early initiation of cholinesterase inhibitor treatment, which will likely stabilize and may possibly reduce the rate of symptomatic cognitive and functional decline. 2007-11-15T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/patcare/452007/471142null XML http://www.modernmedicine.com/modernmedicine/Clinical+Pharmacology/Long-Term-Beta-Carotene-May-Be-Neuroprotective-in-/ArticleNewsFeed/Article/detail/472836?contextCategoryId=40244&ref=25 Beta carotene appears to modestly improve cognitive measures in men who take it for more than 15 years, according to study findings published in the Nov. 12 issue of the Archives of Internal Medicine. 2007-11-14T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/462007/472836/carrots.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/462007/472836null XML