http://www.modernmedicine.com/modernmedicine/Parkinson%27s+Disease/Article/list/40238 Get the latest news about Parkinson’s Disease from Modern Medicine. We are a medical resource for healthcare professionals and provide patient education. 2009-11-21T21:50:38Z http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Study-Finds-Features-Linked-to-Mortality-Risk-in-P/ArticleNewsFeed/Article/detail/641339?contextCategoryId=40238&ref=25 A variety of motor and non-motor factors may be associated with a higher risk of mortality in patients with early Parkinson's disease, according to research published in the November issue of the Archives of Neurology. 2009-11-12T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/462009/641339/parkinsons.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/462009/641339null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/ASTRO-Radiosurgery-May-Be-Beneficial-Tremor-Treatm/ArticleNewsFeed/Article/detail/638897?contextCategoryId=40238&ref=25 In patients with tremors caused by Parkinson's disease and essential tremor, stereotactic radiosurgery may be an effective and noninvasive alternative to other treatments, according to research presented at the 51st Annual Meeting of the American Society for Radiation Oncology, held from Nov. 1 to 5 in Chicago. 2009-11-03T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/452009/638897/parkinsons.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/452009/638897null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Gene-Mutations-Associated-With-Parkinsons-Disease/ArticleNewsFeed/Article/detail/635799?contextCategoryId=40238&ref=25 Mutations in the glucocerebrosidase gene are associated with Parkinson's disease, and mutations are associated with earlier disease onset and atypical clinical symptoms, according to a study in the Oct. 22 New England Journal of Medicine. 2009-10-21T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/432009/635799/Mic030ml.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/432009/635799null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Gene-Therapy-Found-Effective-in-Monkeys-With-Parki/ArticleNewsFeed/Article/detail/634834?contextCategoryId=40238&ref=25 Injecting three genes critical for producing dopamine into the brains of a monkey model of Parkinson's disease corrects the motor problems without inducing the abnormal involuntary movements seen with other treatments, according to a study in the Oct. 14 issue of Science Translational Medicine. 2009-10-16T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/422009/634834/genetics_59175.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/422009/634834null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Urate-Concentrations-Linked-to-Parkinsons-Progress/ArticleNewsFeed/Article/detail/634217?contextCategoryId=40238&ref=25 An increased concentration of the antioxidant urate in the serum or cerebral spinal fluid of a person with Parkinson's disease may slow the progression of clinical disability, according to a study published online Oct. 12 in the Archives of Neurology. 2009-10-14T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/422009/634217/parkinsons.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/422009/634217null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Low-Contrast-Visibility-May-Be-Issue-for-Parkinson/ArticleNewsFeed/Article/detail/631866?contextCategoryId=40238&ref=25 Drivers with Parkinson's disease may be more prone to poor vehicle control and crashes while driving in low-contrast visibility conditions due to issues with perception, cognition and motor dysfunction, according to a study in the Oct. 6 issue of Neurology. 2009-10-06T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/412009/631866/elderly_driver.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/412009/631866null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Efficacy-of-Treatments-for-Overactive-Bladder-Exam/ArticleNewsFeed/Article/detail/630510?contextCategoryId=40238&ref=25 Sacral nerve stimulation and botulinum toxin are effective treatments for overactive bladder, according to two studies in the October issue of the Journal of Urology. 2009-09-30T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/402009/630510/urinespecimen_40025.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/402009/630510null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Drug-May-Slow-Progression-of-Parkinsons-Disease/ArticleNewsFeed/Article/detail/628849?contextCategoryId=40238&ref=25 Early treatment with rasagiline may slow the progression of Parkinson's disease in patients with very mild disease, according to a study in the Sept. 24 issue of the New England Journal of Medicine. 2009-09-23T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/392009/628849/54184.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/392009/628849null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Earlier-Parkinsons-Treatment-Based-on-Disability-E/ArticleNewsFeed/Article/detail/627021?contextCategoryId=40238&ref=25 Patients with early Parkinson's disease are more likely to need treatment earlier with greater impairment, disability, and education level, according to a study in the September issue of Archives of Neurology. 2009-09-16T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/382009/627021/elderly_59328.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/382009/627021null XML http://contemporarypediatrics.modernmedicine.com/contpeds/Adolescent+Medicine+Top+Story/An-integrated-model-for-palliative-care/ArticleStandard/Article/detail/615278?contextCategoryId=40238&ref=25 The words "hospice" and "palliative care" have long made parents cringe -- and they might scare off some pediatricians, too. 2009-07-30T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/contpeds/312009/615278null HTML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Study-Looks-at-Predictors-of-Early-Treatment-in-Pa/ArticleNewsFeed/Article/detail/611378?contextCategoryId=40238&ref=25 Individuals with early Parkinson's disease who are better educated or have greater disability may require earlier symptomatic treatment, according to research published online July 13 in the Archives of Neurology. 2009-07-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/292009/611378/BRAIN.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/292009/611378null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Parkinsons-Drugs-Show-Promise-Against-Tuberculosis/ArticleNewsFeed/Article/detail/608992?contextCategoryId=40238&ref=25 Two existing drugs used for Parkinson's disease may be useful in treating drug-resistant cases of tuberculosis, according to research published July 3 in PLoS Computational Biology. 2009-07-06T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/282009/608992/Tuberculosis.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/282009/608992null XML http://www.modernmedicine.com/modernmedicine/CME+Showcase/Case-studies-in-the-advancement-of-Parkinsons-dise/CME/Article/detail/608769?contextCategoryId=40238&ref=25 Upon completion of the activity, participants will be able toe stimate barriers to early and accurate diagnosis of Parkinson's disease; appraise pharmacologic treatment options for the treatment of Parkinson's disease according to individualized care; and explain efficacy, safety, and tolerability of emerging treatment options available for Parkinson's disease. 2009-07-03T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/cme/geriatrics/272009/608769null REMOTE http://www.modernmedicine.com/modernmedicine/CME+Showcase/Managing-Parkinsons-disease-with-continuous-dopami/CME/Article/detail/608770?contextCategoryId=40238&ref=25 At the conclusion of this activity, participants should be able to discuss the role of continuous dopaminergic stimulation in preventing or reducing the motor complications associated with levodopa (L-dopa) therapy and to describe treatment strategies to improve functional outcomes in patients experiencing motor fluctuations with L-dopa therapy. 2009-07-03T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/cme/geriatrics/272009/608770null REMOTE http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/MDS-Placebo-Effect-Significant-in-Parkinsons-Patie/ArticleNewsFeed/Article/detail/603425?contextCategoryId=40238&ref=25 In Parkinson's disease patients, placebos can mimic the effect of active medication if there is a strong expectation of therapeutic benefit, according to research presented this week at the Movement Disorder Society's 13th International Congress of Parkinson's Disease and Movement Disorders, held from June 7 to 11 in Paris. 2009-06-12T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/242009/603425/femaledoc.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/242009/603425null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Pesticide-Exposure-Associated-With-Parkinsons-Dise/ArticleNewsFeed/Article/detail/603017?contextCategoryId=40238&ref=25 Pesticide exposure, in particular organochlorine insecticide exposure, is associated with the development of Parkinson's disease among agricultural workers in France, according to a study published online April 13 in the Annals of Neurology. 2009-06-11T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/242009/603017/farm_couple.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/242009/603017null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/New-Mouse-Model-of-Parkinsons-Disease-Developed/ArticleNewsFeed/Article/detail/602954?contextCategoryId=40238&ref=25 Using a new technology for inserting large DNA sections into a genome, scientists have successfully created a mouse model of Parkinson's disease that has the same impairments of movement and degenerative brain changes as the human disease, according to a study published online June 7 in Nature Neuroscience. 2009-06-11T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/242009/602954/mouse.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/242009/602954null XML http://www.modernmedicine.com/modernmedicine/Pathology/MDS-No-Evidence-Seen-for-Parkinsonian-Personality/ArticleNewsFeed/Article/detail/602554?contextCategoryId=40238&ref=25 Several personality traits -- including novelty seeking -- are not associated with an increased risk of Parkinson's disease. However, Parkinson's patients treated with dopamine agonist therapy may experience enhanced creativity, according to two studies presented this week at the Movement Disorder Society's 13th International Congress of Parkinson's Disease and Movement Disorders, held from June 7 to 11 in Paris. 2009-06-09T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/242009/602554/parkinsons.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/242009/602554null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Transporter-of-Toxic-Molecules-Damages-Neurons/ArticleNewsFeed/Article/detail/597770?contextCategoryId=40238&ref=25 A protein that transports toxic molecules in the brain plays an important role in the neurodegeneration that occurs due to Parkinson's disease and methamphetamine abuse, according to a study published online April 29 in the Proceedings of the National Academy of Sciences. 2009-05-11T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/202009/597770/parkinsons.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/202009/597770null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Substantia-Nigra-Shows-Role-in-Reinforcement-Learn/ArticleNewsFeed/Article/detail/589574?contextCategoryId=40238&ref=25 Neurons in the substantia nigra appear to play a key role in human reinforcement learning, according to research published online March 13 in Science. 2009-03-26T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/132009/589574/BRAIN.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/132009/589574null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Rodent-Studies-Focus-on-Parkinsons-Treatments/ArticleNewsFeed/Article/detail/588757?contextCategoryId=40238&ref=25 Dorsal column stimulation in animal models of Parkinson's disease points to a less-invasive method of improving function, and the use of optogenetics suggests a major target for deep brain stimulation in the disease, according to two studies published March 20 and online March 19 in Science. 2009-03-23T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/132009/588757/parkinsons.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/132009/588757null XML http://www.modernmedicine.com/modernmedicine/Obstetrics%2FGynecology+%26+Women%27s+Health/How-hormone-exposure-affects-risk-of-Parkinsons/ArticleStandard/Article/detail/586069?contextCategoryId=40238&ref=25 In postmenopausal women, reproductive factors and hormone therapy may affect the risk of Parkinsons's disease, says recent research. 2009-03-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/obgyn/112009/586069null HTML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/AAN-Hormone-Exposure-Affects-Parkinsons-Risk/ArticleNewsFeed/Article/detail/583505?contextCategoryId=40238&ref=25 In postmenopausal women, reproductive factors and hormone therapy use may affect the risk of Parkinson's disease, according to research that will be presented April 25-May 2 at the annual meeting of the American Academy of Neurology in Seattle. 2009-02-25T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092009/583505/parkinsons.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092009/583505null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/AAN-Melanoma-Family-History-Linked-to-Parkinsons-D/ArticleNewsFeed/Article/detail/581998?contextCategoryId=40238&ref=25 A family history of melanoma is associated with an increased risk of developing Parkinson's disease, according to research that will be presented April 25-May 2 at the American Academy of Neurology's 61st Annual Meeting in Seattle. 2009-02-17T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/082009/581998/parkinsons.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/082009/581998null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Parkinsonism-Induced-by-Deep-Brain-Stimulation/ArticleNewsFeed/Article/detail/580873?contextCategoryId=40238&ref=25 Bilateral deep vein stimulation of the globus pallidus internus for craniocervical dystonia induced reversible parkinsonism in a patient who did not have pre-existing bradykinesia, according to a case report published in the February issue of the Journal of Neurosurgery. 2009-02-11T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/072009/580873/BRAIN.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/072009/580873null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Deep-Brain-Stimulation-Benefits-Parkinsons-Patient/ArticleNewsFeed/Article/detail/574047?contextCategoryId=40238&ref=25 In patients with advanced Parkinson's disease, those who receive deep brain stimulation treatment may experience greater improvement in movement skills and quality of life than those who receive conventional therapy, according to a report published in the Jan. 7 issue of the Journal of the American Medical Association. 2009-01-06T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/022009/574047/parkinsons.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/022009/574047null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Abnormal-Sleep-Predicts-Later-Neurodegeneration/ArticleNewsFeed/Article/detail/573370?contextCategoryId=40238&ref=25 Idiopathic REM sleep behavior disorder is a substantial risk factor for the development of neurodegenerative diseases, particularly Parkinson's disease and Lewy body dementia, according to study findings published online Dec. 24 in Neurology. 2008-12-30T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/012008/573370/BRAINsmall.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/012008/573370null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Depression-in-Parkinsons-Responds-to-Treatment/ArticleNewsFeed/Article/detail/572427?contextCategoryId=40238&ref=25 Depression in patients with Parkinson's disease responds to nortriptyline but not paroxetine CR, according to the results of a placebo-controlled trial showing Parkinson's-associated depression can be treated with antidepressant therapy, published online Dec. 17 in the journal Neurology. 2008-12-18T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/512008/572427/parkinsons.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/512008/572427null XML http://www.modernmedicine.com/modernmedicine/CME+Showcase/The-Conundrum-of-Sleep-and-Neurodegenerative-Disea/CME/Article/detail/640951?contextCategoryId=40238&ref=25 Primary and comorbid insomnia are more common than most physicians think, as 1 in 10 Americans has chronic insomnia. 2008-12-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/cme/geriatrics/462009/640951null REMOTE http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Gout-May-Protect-Against-Parkinsons-Disease/ArticleNewsFeed/Article/detail/565889?contextCategoryId=40238&ref=25 Gout is associated with a decreased risk of Parkinson's disease and may have a protective role against the disease, according to research published Nov. 15 in Arthritis Care & Research. 2008-11-13T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/462008/565889/parkinsons.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/462008/565889null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Mediterranean-Diet-Lowers-Risk-of-Death-and-Cancer/ArticleNewsFeed/Article/detail/549497?contextCategoryId=40238&ref=25 Adherence to a Mediterranean diet rich in fruits, vegetables, legumes, cereals and fish, and involving a moderate intake of red wine with meals is associated with a lower risk of death, cancer and Parkinson's and Alzheimer's disease, according to research published online Sept. 11 in BMJ. 2008-09-12T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/372008/549497/fruitveg.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/372008/549497null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/New-Parkinsons-Disease-Patients-Report-More-Pain/ArticleNewsFeed/Article/detail/548647?contextCategoryId=40238&ref=25 During or after the clinical onset of Parkinson's disease, pain should be considered a non-motor feature of the disease, researchers report in the September issue of the Archives of Neurology. 2008-09-09T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/372008/548647/parkinsons.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/372008/548647null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Stem-Cells-Isolated-from-Patients-with-Genetic-Dis/ArticleNewsFeed/Article/detail/535214?contextCategoryId=40238&ref=25 Stem cells can be produced from cells from patients with a variety of genetic disorders, allowing investigation into disease pathogenesis and drug development, according to research published online Aug. 7 in Cell. 2008-08-11T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/332008/535214/genetics_MIC030ML.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/332008/535214null XML http://www.modernmedicine.com/modernmedicine/Pathology/New-Stimulation-Technique-Studied-in-Parkinsons-Di/ArticleNewsFeed/Article/detail/534832?contextCategoryId=40238&ref=25 Parkinsonian symptoms may markedly improve in patients in whom an inhalation anesthetic and microelectrode recordings are used during deep brain stimulation procedures, according to the results of a preliminary study published in the August issue of the Journal of Neurosurgery. 2008-08-08T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/322008/534832/parkinsons.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/322008/534832null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Therapy-Shows-Transient-Benefits-in-Parkinsons-Dis/ArticleNewsFeed/Article/detail/528939?contextCategoryId=40238&ref=25 Treatment with extradural motor cortex stimulation in four patients with Parkinson's disease led to some improvements in the first six months that were largely lost by the end of the year, researchers report in the July issue of the Journal of Neurosurgery. 2008-07-10T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/282008/528939/parkinsons.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/282008/528939null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/MDS-Dopamine-Agonists-Tied-to-Impulse-Control-Diso/ArticleNewsFeed/Article/detail/526310?contextCategoryId=40238&ref=25 People with Parkinson's disease who are treated with dopamine agonists have a higher risk of impulse control disorders, and transdermal delivery of a levodopa ester leads to steady plasma levodopa concentrations, according to two studies presented at the Movement Disorder Society's 12th International Congress of Parkinson's Disease and Movement Disorders, held June 22 to 26 in Chicago. 2008-06-26T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/262008/526310/parkinsons.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/262008/526310null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/MDS-New-Drug-Promising-in-Early-Parkinsons-Disease/ArticleNewsFeed/Article/detail/526159?contextCategoryId=40238&ref=25 Pardoprunox can reduce symptoms in patients with early-stage Parkinson's disease, according to the results of a phase II trial presented at the Movement Disorder Society's 12th International Congress of Parkinson's Disease and Movement Disorders, held June 22 to 26 in Chicago. 2008-06-25T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/262008/526159/parkinsons.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/262008/526159null XML http://www.modernmedicine.com/modernmedicine/Parkinson%27s+Disease/Stimulation-May-Help-Gait-in-Parkinsons-Patients/ArticleNewsFeed/Article/detail/522011?contextCategoryId=40238&ref=25 Functional electrical stimulation can improve some gait-related measurements and reduce falls in patients with Parkinson's disease, with some lasting benefits after discontinuation of use, according to research published in Neuromodulation in April. 2008-06-05T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/232008/522011/33073.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/232008/522011null XML http://www.modernmedicine.com/modernmedicine/Internal+Medicine/Drug-Reduced-Symptoms-in-Parkinsons-Patients/ArticleNewsFeed/Article/detail/521504?contextCategoryId=40238&ref=25 Treatment with istradefylline resulted in a reduction in daily awake time in the "off" state in patients with Parkinson's disease, without a significant increase in "on" time with troublesome dyskinesia, according to research published in the June 3 issue of Neurology. 2008-06-04T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/232008/521504/BRAIN.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/232008/521504null XML http://www.modernmedicine.com/modernmedicine/GERIATRICS/Management-of-motor-and-non-motor-complications-in/ArticleStandard/Article/detail/518679?contextCategoryId=40238&ref=25 The prevalence of neurodegenerative diseases such as Parkinson's disease increases with age, and in an aging population, an understanding of the management of late complications of Parkinson's disease is becoming ever more important. 2008-05-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/geriatrics/212008/518679null XML http://www.modernmedicine.com/modernmedicine/Neurology/Electrode-Adjustment-May-Help-Parkinsons-Patients/ArticleNewsFeed/Article/detail/516658?contextCategoryId=40238&ref=25 Reimplantation of electrodes in patients with Parkinson's disease who responded poorly to subthalamic nucleus stimulation can result in improved motor scores, according to research published in the May issue of the Archives of Neurology. 2008-05-13T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/202008/516658/BRAIN.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/202008/516658null XML http://www.modernmedicine.com/modernmedicine/Focus+On/Istradefylline-An-adenosine-receptor-antagonist-fo/ArticleStandard/Article/detail/514839?contextCategoryId=40238&ref=25 Istradefylline, a highly selective adenosine A2A receptor antagonist, is a new agent being investigated for the adjunctive treatment of the motor signs and symptoms of idiopathic Parkinson disease. 2008-05-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/formulary/192008/514839null XML http://www.modernmedicine.com/modernmedicine/Neurology/AANS-Novel-Agent-Effective-in-Parkinsons-Disease/ArticleNewsFeed/Article/detail/512800?contextCategoryId=40238&ref=25 In patients with moderate to advanced Parkinson's disease, the use of Spheramine is safe and effective, according to preliminary research presented this week at the annual meeting of the American Association of Neurological Surgeons in Chicago. 2008-04-28T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/182008/512800/parkinsons.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/182008/512800null XML http://www.modernmedicine.com/modernmedicine/Internal+Medicine/Mutations-Linked-to-Higher-Parkinsons-Disease-Risk/ArticleNewsFeed/Article/detail/510044?contextCategoryId=40238&ref=25 Relatives of early-onset Parkinson's disease patients who carry a mutation in the Parkin gene have a significantly higher risk of developing the disease before 65 years of age, according to study findings published in the April issue of the Archives of Neurology. 2008-04-14T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/162008/510044/genetics_MIC028ML.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/162008/510044null XML http://www.modernmedicine.com/modernmedicine/Treatment+Areas/Neupro-patches-recalled-due-to-crystallization/ArticleStandard/Article/detail/509942?contextCategoryId=40238&ref=25 Schwarz Pharma recalls rotigotine transdermal system after crystals form in patch. 2008-04-14T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/drugtopics/162008/509942null HTML http://www.modernmedicine.com/modernmedicine/Parkinson%27s+Disease/Parkinsons-Tissue-Transplant-Shows-Signs-of-Diseas/ArticleNewsFeed/Article/detail/509134?contextCategoryId=40238&ref=25 The embryonic stem cell graft received by a woman with Parkinson's disease 14 years ago shows characteristic signs of the disease, suggesting that the graft is as susceptible as the host neurons to the disease process, according to a report published online April 6 in Nature Medicine. 2008-04-09T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/152008/509134/parkinsons.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/152008/509134null XML http://www.modernmedicine.com/modernmedicine/Parkinson%27s+Disease/Therapeutic-Cloning-Improves-Parkinsons-in-Mice/ArticleNewsFeed/Article/detail/504801?contextCategoryId=40238&ref=25 Individually matched neurons derived from embryonic stem cells made by therapeutic cloning can improve the symptoms of Parkinson's disease in mice, according to a report published online March 23 in Nature Medicine. 2008-03-24T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/132008/504801/parkinsons.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/132008/504801null XML http://www.modernmedicine.com/modernmedicine/Parkinson%27s+Disease/Impaired-Smell-May-Be-Risk-Factor-for-Parkinsons-D/ArticleNewsFeed/Article/detail/505041?contextCategoryId=40238&ref=25 Impaired olfaction could be a useful screening tool for Parkinson's disease in men, as it can predate the disease by at least four years, according to a report published in the February issue of the Annals of Neurology. 2008-03-24T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/132008/505041/smell_18115.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/132008/505041null XML http://www.modernmedicine.com/modernmedicine/Psychiatry+%26+Behavioral+Health/Parkinsonian-Syndrome-Seen-in-Methcathinone-Users/ArticleNewsFeed/Article/detail/500625?contextCategoryId=40238&ref=25 Chronic use of injected methcathinone, an analogue of methamphetamine, can lead to a Parkinsonian syndrome caused by elevated blood manganese levels, according to an article published in the March 6 issue of the New England Journal of Medicine. 2008-03-05T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/102008/500625/blood_MIC029ML.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/102008/500625null XML http://www.modernmedicine.com/modernmedicine/Geriatrics/Mouse-Study-Shines-Light-on-MAO-B-Role-in-Parkinso/ArticleNewsFeed/Article/detail/493058?contextCategoryId=40238&ref=25 High levels of monoamine oxidase B (MAO-B) caused Parkinson's disease-like symptoms in a novel transgenic mouse model genetically engineered to overexpress the enzyme, according to research published online Feb. 20 in PLoS One. 2008-02-20T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/082008/493058/mouse.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/082008/493058null XML http://www.modernmedicine.com/modernmedicine/Cardiology/Calcium-Channel-Blockers-May-Decrease-Parkinsons-R/ArticleNewsFeed/Article/detail/489978?contextCategoryId=40238&ref=25 Long-term use of calcium channel blockers to control blood pressure may have an added effect of slightly decreasing the risk of developing Parkinson's disease, according to research published online Feb. 6 in Neurology. 2008-02-07T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/062008/489978/elderlycouple.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/062008/489978null XML http://www.modernmedicine.com/modernmedicine/Neurology/L-DOPA-Side-Effects-May-Be-Controllable/ArticleNewsFeed/Article/detail/490070?contextCategoryId=40238&ref=25 While long-term treatment of Parkinson's disease with L-DOPA may lead to abnormal behaviors and movements, the use of 5-HT1B receptor agonists may provide an alternative approach in managing these adverse effects, according to research published online Feb. 6 in the Proceedings of the National Academy of Sciences Early Edition. 2008-02-07T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/062008/490070/BRAIN.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/062008/490070null XML http://www.modernmedicine.com/modernmedicine/Neurology/Axon-Guidance-Gene-Variants-Predict-ALS/ArticleNewsFeed/Article/detail/486428?contextCategoryId=40238&ref=25 Gene variants involved in axon guidance in amyotrophic lateral sclerosis (ALS) predict susceptibility, survival free of disease and age of disease onset, according to a report published online Jan. 16 in PLoS ONE. 2008-01-23T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/042008/486428/dna20.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/042008/486428null XML http://www.modernmedicine.com/modernmedicine/Cardiology/Pergolide-Increases-Valve-Disease-Risk-in-Parkinso/ArticleNewsFeed/Article/detail/479859?contextCategoryId=40238&ref=25 Treating patients with Parkinson's disease with pergolide, a dopamine receptor agonist, increases the risk of moderate to severe heart valve disease in a dose-dependent manner, researchers report in the December issue of the Archives of Neurology. 2007-12-17T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/512007/479859/heart4.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/512007/479859null XML http://www.modernmedicine.com/modernmedicine/Psychiatry+%26+Behavioral+Health/Relatives-of-Parkinsons-Patients-Prone-to-Depressi/ArticleNewsFeed/Article/detail/477781?contextCategoryId=40238&ref=25 Relatives of patients with Parkinson's disease are more prone to depression and anxiety than those with no family members affected by the disease, according to a study published in the December issue of the Archives of General Psychiatry. 2007-12-06T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/492007/477781/somberwoman.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/492007/477781null XML http://www.modernmedicine.com/modernmedicine/Neurology/PET-Scans-Show-Brain-Changes-After-Gene-Therapy/ArticleNewsFeed/Article/detail/476403?contextCategoryId=40238&ref=25 Following gene therapy delivered into the subthalamic nucleus, patients with Parkinson's disease showed improvements in regional and network-related metabolic activity as observed by positron emission tomography, according to research published online Nov. 27 in the Proceedings of the National Academy of Sciences Early Edition. 2007-11-29T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/482007/476403/BRAIN.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/482007/476403null XML http://www.modernmedicine.com/modernmedicine/Geriatrics/Two-Studies-Provide-New-Insights-Into-Parkinsons/ArticleNewsFeed/Article/detail/473509?contextCategoryId=40238&ref=25 Two studies published in the Archives of Neurology in November provide new tools and insight into managing Parkinson's disease. 2007-11-16T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/462007/473509/seniorshands_40114.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/462007/473509null XML http://www.modernmedicine.com/modernmedicine/Parkinson%27s+Disease/NSAIDs-May-Be-Neuroprotective/ArticleNewsFeed/Article/detail/470601?contextCategoryId=40238&ref=25 The neuroprotective function of non-steroidal anti-inflammatory drugs (NSAIDs) may give them a protective role against Parkinson's disease, according to research published in the Nov. 6 issue of Neurology. 2007-11-06T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/452007/470601/pills_MIC067ML.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/452007/470601null XML http://www.modernmedicine.com/modernmedicine/Focus+On/Rotigotine-The-first-transdermal-nonergot-derived-/ArticleStandard/Article/detail/476083?contextCategoryId=40238&ref=25 Parkinson disease (PD) is a chronic, progressive neurodegenerative disorder affecting approximately 1% of people aged >60 years. Levodopa has long been the cornerstone of PD treatment, but many patients receiving long-term levodopa therapy experience dyskinesia and motor fluctuations. Dopamine agonists act directly on dopamine receptors and are associated with a lower incidence of dyskinesias. There are 2 subclasses of dopamine agonists: ergot-derived and nonergot-derived. The use of ergot-derived dopamine agonists has declined in recent years due to the agents' association with valvular heart disease. Nonergot-derived dopamine agonists such as ropinirole and pramipexole are used more widely in the treatment of PD. Rotigotine is a nonergot-derived dopamine agonist that was approved by FDA on May 9, 2007, for the treatment of early-stage idiopathic PD. Rotigotine is the first approved nonergot-derived dopamine agonist that is delivered continuously through a transdermal silicone-based patch that is replaced.. 2007-11-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/formulary/482007/476083null XML http://www.modernmedicine.com/modernmedicine/Internal+Medicine/Gout-Offers-Some-Protection-Against-Parkinsons-Dis/ArticleNewsFeed/Article/detail/467497?contextCategoryId=40238&ref=25 Older men who have gout are less likely to develop Parkinson's disease, but this protection does not appear to extend to women, researchers report in the Oct. 23 issue of Neurology. 2007-10-23T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/432007/467497/gout.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/432007/467497null XML http://www.modernmedicine.com/modernmedicine/Endocrinology/Parkinsons-Not-Linked-to-Diabetes-Hypertension/ArticleNewsFeed/Article/detail/466962?contextCategoryId=40238&ref=25 Researchers investigating the possibility that vascular factors may influence the risk of Parkinson's disease found no significant association between hypertension or diabetes and Parkinson's. The study findings are published in the Oct. 23 issue of Neurology. 2007-10-22T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/432007/466962/BRAIN.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/432007/466962null XML http://www.modernmedicine.com/modernmedicine/Neurology/Parkinsons-Disease-Relatives-at-Risk-for-Dementia/ArticleNewsFeed/Article/detail/464950?contextCategoryId=40238&ref=25 Relatives of patients with Parkinson's disease are at increased risk of cognitive impairment or dementia, and the two diseases may share familial susceptibility, according to the results of a study published in the October issue of the Archives of Neurology. 2007-10-12T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/412007/464950/caregiver.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/412007/464950null XML http://www.modernmedicine.com/modernmedicine/Internal+Medicine/Gene-Mutation-Linked-to-Early-Onset-of-Parkinson-D/ArticleNewsFeed/Article/detail/457969?contextCategoryId=40238&ref=25 Mutations in the glucocerebrosidase (GBA) gene are associated with Parkinson disease, especially in Jewish patients, and those with early onset of the disease regardless of ethnicity, according to a report in the Sept. 18 issue of Neurology. 2007-09-17T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/382007/457969/genetics_59175.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/382007/457969null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/201807573/ArticleStandard/Article/detail/541472?contextCategoryId=40238&ref=25 2007-09-15T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/332008/541472null XML http://www.modernmedicine.com/modernmedicine/FDA+Approvals/Exelon-patch-New-formulation-recently-approved-by-/ArticleStandard/Article/detail/457000?contextCategoryId=40238&ref=25 A new formulation for rivastigmine; a transdermal formulation of cholinesterase inhibitor approved for the treatment of mild-to-moderate dementia of the AD type and mild-to-moderate dementia associated with PD. 2007-09-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/formulary/372007/457000null XML http://www.modernmedicine.com/modernmedicine/Neurology/Pre-Menopausal-Oophorectomy-Linked-to-Brain-Disord/ArticleNewsFeed/Article/detail/453664?contextCategoryId=40238&ref=25 Women who undergo oophorectomy before menopause may be at higher risk of developing cognitive impairment, dementia or Parkinson disease, suggesting that estrogen plays a neuroprotective role, according to two studies published online Aug. 29 in Neurology. 2007-08-30T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/352007/453664/BRAIN.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/352007/453664null XML http://www.modernmedicine.com/modernmedicine/Neurology/Statin-Use-Associated-with-Reduced-Dementia-Risk/ArticleNewsFeed/Article/detail/444865?contextCategoryId=40238&ref=25 Simvastatin use is associated with a reduction in dementia and Parkinson disease incidence in patients taking the drug, according to a report published July 19 in BMC Medicine. 2007-07-27T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/302007/444865/59005.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/302007/444865null XML http://www.modernmedicine.com/modernmedicine/Parkinson%27s+Disease/Tobacco-Use-Associated-with-Reduced-Parkinsons-Ris/ArticleNewsFeed/Article/detail/441566?contextCategoryId=40238&ref=25 A history of tobacco use is indeed associated with a significantly reduced risk of Parkinson disease, according to the first pooled analysis of data. The results, published in the July issue of the Archives of Neurology, suggest that there is a risk reduction in ex-smokers as well as in pipe and cigar smokers. 2007-07-13T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/282007/441566/SS42038.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/282007/441566null XML http://www.modernmedicine.com/modernmedicine/Parkinson%27s+Disease/Start-of-Parkinsons-Therapy-Linked-to-Hallucinatio/ArticleNewsFeed/Article/detail/440728?contextCategoryId=40238&ref=25 Patients with early Parkinson disease may have an increased risk of developing hallucinations, sleepiness and edema when they start dopaminergic treatment, researchers report in the July 10 issue of Neurology. 2007-07-10T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/282007/440728/33097.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/282007/440728null XML http://www.modernmedicine.com/modernmedicine/CME+Showcase/Parkinsons-Disease-CME/CME/Article/detail/641070?contextCategoryId=40238&ref=25 Parkinson's Disease (American College of Physicians PIER) 2007-07-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/cme/geriatrics/462009/641070null REMOTE http://www.modernmedicine.com/modernmedicine/FDA+Approvals/Neupro-Rotigotine-transdermal-system-recently-appr/ArticleStandard/Article/detail/442852?contextCategoryId=40238&ref=25 Rotigotine transdermal system is now approved by FDA as a nonergoline dopamine agonist for the treatment of for the treatment of signs and symptoms of early-stage idiopathic Parkinson disease. 2007-07-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/formulary/292007/442852null XML http://www.modernmedicine.com/modernmedicine/Parkinson%27s+Disease/Stem-Cells-Curb-Parkinsonian-Symptoms-in-Monkeys/ArticleNewsFeed/Article/detail/437684?contextCategoryId=40238&ref=25 Injection of human neural stem cells helps produce the neurotransmitter dopamine and reduce symptoms in a primate model of Parkinson disease, according to a report published online June 22 in the Proceedings of the National Academy of Sciences Early Edition. 2007-06-26T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/262007/437684/shot_59016.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/262007/437684null XML http://www.modernmedicine.com/modernmedicine/Internal+Medicine/Gene-Therapy-for-Parkinsons-Completes-Phase-I-Tria/ArticleNewsFeed/Article/detail/436958?contextCategoryId=40238&ref=25 Gene therapy for Parkinson disease using an adeno-associated virus-borne glutamic acid decarboxylase gene was safe and well tolerated in a phase I trial, and shows promise as a treatment for neurodegenerative disease, according to study findings published in the June 23 issue of The Lancet. 2007-06-22T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/252007/436958/genetics_59175.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/252007/436958null XML http://www.modernmedicine.com/modernmedicine/Primary+Care+Medicine/Parkinson-Disease-Linked-to-Pesticide-Exposure/ArticleNewsFeed/Article/detail/431147?contextCategoryId=40238&ref=25 Exposure to pesticides and traumatic head injury may increase the risk of Parkinson disease and other degenerative parkinsonian syndromes, according to a report published online May 30 in the journal Occupational and Environmental Medicine. 2007-06-01T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/222007/431147/cropduster.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/222007/431147null XML http://www.modernmedicine.com/modernmedicine/Neurology/Coenzyme-Q10-Does-Not-Help-Parkinson-Disease-Patie/ArticleNewsFeed/Article/detail/426700?contextCategoryId=40238&ref=25 Treating Parkinson disease patients with daily doses of coenzyme Q10 appears to have no impact on their symptoms, according to the results of a randomized trial published May 14 in the Archives of Neurology. 2007-05-14T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/202007/426700/33101.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/202007/426700null XML http://www.modernmedicine.com/modernmedicine/Neurology/Parkinsons-disease/CustomizableHandout/Article/detail/554803?contextCategoryId=40238&ref=25 Parkinson's disease is a disorder of the brain that leads to shaking (tremors) and difficulty with walking, movement, and coordination. 2007-05-10T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/customizablehandout/modernmedicine/402008/554803null XML http://www.modernmedicine.com/modernmedicine/Neurology/FDA-OKs-Dopamine-Agonist-Patch-for-Parkinson-Disea/ArticleNewsFeed/Article/detail/426124?contextCategoryId=40238&ref=25 The U.S. Food and Drug Administration has approved the first transdermal patch to treat the symptoms of Parkinson disease. The Neupro Patch, manufactured by Schwarz Bioscience of Research Triangle Park, N.C., contains the dopamine agonist rotigotine, previously not approved in the United States. 2007-05-10T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/192007/426124/BRAIN.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/192007/426124null XML http://www.modernmedicine.com/modernmedicine/Neurology/Secondary-parkinsonism/CustomizableHandout/Article/detail/554807?contextCategoryId=40238&ref=25 Secondary parkinsonism is similar to Parkinson's disease, but is caused by certain medicines, an different nervous system disorder, or another illness. 2007-05-09T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/customizablehandout/modernmedicine/402008/554807null XML http://www.modernmedicine.com/modernmedicine/Psychiatry+%26+Behavioral+Health/AAN-Depression-May-Be-Early-Sign-of-Parkinson-Dise/ArticleNewsFeed/Article/detail/422983?contextCategoryId=40238&ref=25 Current antidepressant use is associated with nearly double the risk of developing Parkinson disease, suggesting that depression may be an early symptom of the disease, according to research presented this week at the annual meeting of the American Academy of Neurology in Boston. 2007-04-27T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/172007/422983/seniors_40121.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/172007/422983null XML http://www.modernmedicine.com/modernmedicine/Parkinson%27s+Disease/AAN-Dopamine-Medications-Affect-Reward-Behavior/ArticleNewsFeed/Article/detail/422577?contextCategoryId=40238&ref=25 Medications that increase or decrease dopamine levels, such as levodopa or haloperidol, may strongly influence reward-seeking behavior, according to research presented this week at the annual meeting of the American Academy of Neurology in Boston. 2007-04-26T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/172007/422577/gambling.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/172007/422577null XML http://www.modernmedicine.com/modernmedicine/Sports+Medicine/AAN-Exercise-Linked-to-Lower-Parkinson-Disease-Ris/ArticleNewsFeed/Article/detail/421739?contextCategoryId=40238&ref=25 Older people who engage in regular moderate or vigorous physical activity may have a lower risk of developing Parkinson disease, according to research presented this week at the annual meeting of the American Academy of Neurology in Boston. 2007-04-23T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/172007/421739/treadmill_18277.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/172007/421739null XML http://www.modernmedicine.com/modernmedicine/Hypertension/Smoking-Caffeine-Linked-to-Lower-Parkinson-Disease/ArticleNewsFeed/Article/detail/419322?contextCategoryId=40238&ref=25 Smoking and caffeine, but not non-steroidal anti-inflammatory drugs, appear to protect against Parkinson disease, according to a report published in the April issue of the Archives of Neurology. 2007-04-09T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/152007/419322/Ss39055.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/152007/419322null XML http://www.modernmedicine.com/modernmedicine/Managed+Care/Pergolide-Products-Recalled-Due-to-Heart-Valve-Dam/ArticleNewsFeed/Article/detail/415709?contextCategoryId=40238&ref=25 The U.S. Food and Drug Administration and manufacturers have voluntarily recalled pergolide drug products used to treat Parkinson disease because they can cause serious damage to patients' heart valves. 2007-03-30T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/132007/415709/BRAINsmall.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/132007/415709null XML http://www.modernmedicine.com/modernmedicine/Managed+Care/Pergolide-Products-Recalled-Due-to-Heart-Valve-Dam/ArticleNewsFeed/Article/detail/498567?contextCategoryId=40238&ref=25 The U.S. Food and Drug Administration and manufacturers have voluntarily recalled pergolide drug products used to treat Parkinson disease because they can cause serious damage to patients' heart valves. 2007-03-30T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092008/498567/BRAINsmall.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092008/498567null XML http://www.modernmedicine.com/modernmedicine/Endocrinology/Type-2-Diabetes-Associated-with-Parkinson-Disease-/ArticleNewsFeed/Article/detail/414966?contextCategoryId=40238&ref=25 Type 2 diabetes is associated with an increased risk for Parkinson disease in old age, according to a report in the April issue of Diabetes Care. 2007-03-28T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/132007/414966/33101.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/132007/414966null XML http://www.modernmedicine.com/modernmedicine/Internal+Medicine/Risedronate-Cuts-Fracture-Risk-in-Men-with-Parkins/ArticleNewsFeed/Article/detail/498487?contextCategoryId=40238&ref=25 The bone resorption inhibitor, risedronate, can increase bone mineral density and reduce the risk of hip fracture in elderly men with Parkinson disease, according to a report in the March 20 issue of Neurology. 2007-03-20T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092008/498487/bone_SS36097.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092008/498487null XML http://www.modernmedicine.com/modernmedicine/Internal+Medicine/Risedronate-Cuts-Fracture-Risk-in-Men-with-Parkins/ArticleNewsFeed/Article/detail/413091?contextCategoryId=40238&ref=25 The bone resorption inhibitor, risedronate, can increase bone mineral density and reduce the risk of hip fracture in elderly men with Parkinson disease, according to a report in the March 20 issue of Neurology. 2007-03-20T04:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/122007/413091/bone_SS36097.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/122007/413091null XML http://www.modernmedicine.com/modernmedicine/Dermatology/Dermatology-pioneer-Aaron-Lerner-Yale-chairman-die/ArticleStandard/Article/detail/408910?contextCategoryId=40238&ref=25 New Haven, Conn. — Aaron Lerner, M.D., a native Minnesotan and Yale University School of Medicine professor whose research led to treatments for skin diseases, died Feb. 3 of complications from Parkinson’s disease in New Haven, Conn., the Minneapolis Star Tribune reports. He was 86. 2007-03-05T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/102007/408910null HTML http://www.modernmedicine.com/modernmedicine/Neurology/Parkinson-Linked-Gambling-Higher-with-Past-Alcohol/ArticleNewsFeed/Article/detail/498257?contextCategoryId=40238&ref=25 Parkinson disease patients are at higher risk of developing pathological gambling after treatment with dopamine agonists if they developed Parkinson disease at a relatively young age, have a history of alcohol abuse or have more novelty-seeking traits, according to a study in the February issue of the Archives of Neurology. 2007-02-12T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092008/498257/gambling.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092008/498257null XML http://www.modernmedicine.com/modernmedicine/Parkinson%27s+Disease/Blood-Test-May-Help-Identify-Early-Parkinson-Disea/ArticleNewsFeed/Article/detail/497877?contextCategoryId=40238&ref=25 A blood-based gene expression profile may help in the early detection of Parkinson disease, according to a report published online Jan. 10 in the Proceedings of the National Academy of Sciences Early Edition. 2007-01-11T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092008/497877/blood_MIC023ML.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092008/497877null XML http://www.modernmedicine.com/modernmedicine/Neurology/Zonisamide-Safe-Effective-in-Parkinson-Disease/ArticleNewsFeed/Article/detail/497763?contextCategoryId=40238&ref=25 The anti-epileptic drug zonisamide is a safe, effective and well-tolerated adjunctive treatment in doses up to 100 mg per day for patients with Parkinson disease, researchers report in the January issue of Neurology. 2007-01-03T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092008/497763/pillbottle_59037.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092008/497763null XML http://www.modernmedicine.com/modernmedicine/Clinical+Pharmacology/Studies-Link-Valve-Problems-to-Ergot-Dopamine-Agon/ArticleNewsFeed/Article/detail/497816?contextCategoryId=40238&ref=25 The risk of cardiac-valve regurgitation is higher in patients with Parkinson disease taking ergot-derived dopamine agonists compared with those taking non-ergot-derived agonists, according to the results of two studies published in the Jan. 4 issue of the New England Journal of Medicine. 2007-01-03T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092008/497816/hch008.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092008/497816null XML http://www.modernmedicine.com/modernmedicine/Gastroenterology/CASE-amp-COMMENT-Severe-prostration-with-fever-and/ArticleStandard/Article/detail/397166?contextCategoryId=40238&ref=25 2007-01-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/patcare/022007/397166null XML http://www.modernmedicine.com/modernmedicine/Newsbrief/Largest-biobank-proposed/ArticleStandard/Article/detail/396319?contextCategoryId=40238&ref=25 Iowa City, Iowa — The National Genecular Institute (NGI) has announced it is creating the largest known global tissue and genetic storage facility here. 2007-01-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/dermatologytimes/022007/396319null XML http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/Low-LDL-Levels-Linked-to-Parkinsons-Risk/ArticleStandard/Article/detail/538579?contextCategoryId=40238&ref=25 CHAPEL HILL, N.C. -- Low levels of LDL cholesterol appear to confer a greater risk of Parkinson's disease, suggesting that it's possible to have too little of a bad thing, researchers here reported. 2006-12-20T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/modernmedicine/332008/538579null XML http://www.modernmedicine.com/modernmedicine/Medical+Economics+magazine/Healthcare-Hot-again-in-07/ArticleStandard/Article/detail/390155?contextCategoryId=40238&ref=25 Perspective 2006-12-15T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/memag/492006/390155null XML http://www.modernmedicine.com/modernmedicine/Internal+Medicine/Psychosis-related-disturbances/ArticleStandard/Article/detail/393879?contextCategoryId=40238&ref=25 Approximately 50% to 80% of persons diagnosed with Alzheimer's disease (AD) have some type of behavioral or psychiatric condition (eg, agitation, psychosis, and/or disinhibition). Agitation is defined in the context of restlessness, irritability, and resistiveness. Psychosis is recognized as a disturbance in the perception of objective reality. Disinhibition means a chronic loss of social restraint. In the case of AD, disinhibition can present as aggression, hyperactivity, and socially intrusive behavior. Such conditions can be burdensome for physicians and caregivers to manage. Consequences may include caregiver burnout or illness, patient abuse, and even institutionalization for the patient. Management of behavioral disturbances is no longer primarily handled by psychiatrists, but is now entering the realm of family practice and primary care. This article provides evaluation methods and treatment options for the aforementioned behavioral disturbances. 2006-12-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/geriatrics/512006/393879null XML http://www.modernmedicine.com/modernmedicine/Internal+Medicine/CASE-amp-COMMENT-New-onset-ptosis/ArticleStandard/Article/detail/391524?contextCategoryId=40238&ref=25 S 2006-12-01T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlestandard/patcare/502006/391524null XML http://www.modernmedicine.com/modernmedicine/Parkinson%27s+Disease/Driving-Errors-More-Frequent-in-Parkinson-Patients/ArticleNewsFeed/Article/detail/497382?contextCategoryId=40238&ref=25 Patients with Parkinson disease make more safety errors while driving and are more than twice as likely to make errors while distracted, researchers report in the Nov. 28 issue of Neurology. 2006-11-28T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092008/497382/elderly_driver.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092008/497382null XML http://www.modernmedicine.com/modernmedicine/Neurology/iLRRK2i-Overactivation-Linked-to-Parkinson-Disease/ArticleNewsFeed/Article/detail/497355?contextCategoryId=40238&ref=25 Mutations in the LRRK2 gene reduce neurite length and branching, and may contribute to the development of Parkinson disease, according to in vitro and animal research published in the Nov. 22 issue of Neuron. 2006-11-22T05:00:00Z http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092008/497355/BRAINsmall.jpg http://www.modernmedicine.com/modernmedicine/data/articlenewsfeed/modernmedicine/092008/497355null XML