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    Survival Same Despite Dialysis Mode After Allograft Loss

    After renal transplant failure, hemodialysis and peritoneal dialysis have similar survival rate

    MONDAY, Jan. 17 (HealthDay News) -- Among patients returning to dialysis after allograft loss (DAGL), no difference was found in survival rates between those treated with peritoneal dialysis and those treated with hemodialysis, according to research published online Jan. 13 in the Clinical Journal of the American Society of Nephrology.

    Jeffrey Perl, M.D., of the University of Toronto, and colleagues conducted a registry-based study of 2,110 adult patients who began dialysis after failure of their first kidney transplant between 1991 and 2005. Of these, 1,721 patients were treated with hemodialysis and 389 were treated with peritoneal dialysis. The researchers took data from the Canadian Organ Replacement Register, a national registry of dialysis and organ transplant recipients.

    The researchers found that hemodialysis- and peritoneal-dialysis-treated patients had no difference in overall survival (hazard ratio, 1.05; 95 percent confidence interval, 0.85 to 1.31). Similar results were seen for survival in the first two years and survival after two years, with no difference in mortality between patients receiving hemodialysis and peritoneal dialysis, when adjusted for covariates. More contemporary cohorts of patients returning to DAGL showed improved survival.

    "Our findings provide a basis for the feasibility and safety regarding the use of peritoneal dialysis in this patient population," the authors write.

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