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    Endocrinology & Diabetes E-news - 182010

    Endocrinology & Diabetes E-news - 18/2010

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    Liraglutide Found Superior to Sitagliptin for Glycemic Control
    POSTED: April 23, 2010
    In type 2 diabetes patients who have inadequate glycemic control on metformin therapy, liraglutide injections are well tolerated and are more effective than oral sitagliptin in reducing HbA1C, according to a study in the April 24 issue of The Lancet.

    AACE: Hydrogel Increases Feelings of Satiety After Meals
    POSTED: April 23, 2010
    Attiva -- a superabsorbent hydrogel -- may significantly increase feelings of satiety after meals and reduce hunger between meals in obese patients, according to research presented at the annual meeting of the American Association of Clinical Endocrinologists, held from April 21 to 25 in Boston.

    In Diabetes Patients, Modifiable Factors Up Risk of Cesarean
    POSTED: April 23, 2010
    Nulliparous women with type 1 diabetes mellitus have a high rate of cesarean delivery, and their potentially modifiable risk factors for cesarean delivery include pre-pregnancy body weight, gestational weight gain, and accuracy of the prediction of fetal macrosomia, according to a study published in the May issue of Obstetrics & Gynecology.

    Stress Hormones May Promote Ovarian Cancer Metastasis
    POSTED: April 23, 2010
    In patients with ovarian cancer, focal adhesion kinase modulation by stress hormones -- especially norepinephrine and epinephrine -- may contribute to tumor progression, according to research published online April 12 in the Journal of Clinical Investigation.

    In Utero Methadone Exposure Linked to Vision Problems
    POSTED: April 22, 2010
    Infants born to women who misused drugs and were prescribed methadone during pregnancy are at risk for a range of vision problems, and those with neonatal abstinence syndrome severe enough to receive pharmaceutical treatment may especially be at risk for developing nystagmus, according to a report published online April 21 in the British Journal of Ophthalmology.

    FDA Adds Boxed Warning to Propylthiouracil Label
    POSTED: April 22, 2010
    The U.S. Food and Drug Administration has added a boxed warning to the label of propylthiouracil due to the risk of serious liver injury -- which in some cases may be fatal -- in adult and pediatric patients.

    Added Sugars Linked to Measures of Dyslipidemia
    POSTED: April 20, 2010
    Greater consumption of added sugars in foods is associated with cardiovascular risk factors including lower high-density lipoprotein cholesterol and higher triglyceride levels, according to research published in the April 21 issue of the Journal of the American Medical Association.

    Long-Term Effects of Sucrose in Infants Unclear
    POSTED: April 20, 2010
    Little is known about the potential long-term developmental effects of early dietary exposure to sugar, and physicians should be conservative in their use of sucrose to ameliorate pain in preterm and critically ill infants, according to research published online April 19 in Pediatrics.

    Early Antivirals Decrease H1N1 Mortality in Pregnant Women
    POSTED: April 20, 2010
    Pregnant women with influenza A(H1N1) have a high risk of mortality, although early antiviral treatment is associated with fewer intensive care unit admissions and lower mortality, according to research published in the April 21 issue of the Journal of the American Medical Association.

    Nanoparticles May Have Role Against Autoimmune Diseases
    POSTED: April 19, 2010
    Nanoparticles coated with peptide-major histocompatibility complexes can successfully reverse diabetes in a mouse model of the disease, with research suggesting that this approach could be used against other autoimmune diseases, according to a study published online April 8 in Immunity.

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