Michael G Burke, MD
FDA’s youth antismoking campaign boasts good results
Exposure to the US Food and Drug Administration (FDA) youth-specific national antismoking media campaign—The Real Cost—was associated with preventing young persons from beginning to smoke.
Crizanlizumab helps prevent pain crises in sickle cell disease
In patients with sickle cell disease, therapy with crizanlizumab, an antibody against the adhesion molecule P-selectin, resulted in a significantly lower rate of sickle cell-related pain crises than placebo, a trial in 198 patients aged from 16 to 65 years showed.
Age-restricted supplements sold to male teens
Sales associates at health food stores, which primarily sell dietary supplements, often recommend creatine products and, sometimes, testosterone boosters to young teenaged boys, according to a study involving 244 stores in 49 states.
LCPUFAs in pregnancy lower child’s asthma risk
Women in the third trimester of pregnancy who take supplements of n-3 long-chain polyunsaturated fatty acids (LCPUFAs) reduce their children’s risk of persistent wheeze or asthma as well as of lower respiratory tract infections, a study in Denmark demonstrated.
Meningococcal vaccine might raise risk of Bell’s palsy
In a study of almost 48,900 vaccinated individuals, investigators observed a temporal association between development of Bell’s palsy and administration of quadrivalent meningococcal conjugate vaccine (MCV4) that protects against serogroups A,C, Y, and W (MenACWY) when the vaccine was given at the same time as other vaccines.
Two-step egg introduction helps prevent egg allergy
Stepwise introduction of egg (starting with a low dose, which is then increased), along with aggressive treatment of atopic dermatitis (AD), is a safe and effective way to prevent hen’s egg allergy in high-risk infants, a study in Japan showed.
Top 10 studies you may have missed- 2017
It’s that time again! Here are Dr Michael Burke’s favorite 10 articles he reviewed in Journal Club for Contemporary Pediatrics during the past 12 months that are most likely to change your practice, improve patient care, or illuminate future trends in pediatrics.
How to evaluate young febrile infants
A large retrospective study of how infants with fever without a cause are evaluated found that physicians are selective in deciding which of these babies will have blood, urine, or cerebral spinal fluid cultures.
How best to reduce injection pain—lidocaine cream
A comparison of 4 levels of pain management of routine vaccine injections found that of the remedies tried, only liposomal lidocaine applied at the injection site provided consistent relief.
Limiting duration of antibiotics in OM limits their effectiveness
Treating children with acute otitis media with amoxicillin-clavulanate for 5 days is less effective than following standard 10-day treatment, according to a study in 520 such children who were aged 6 to 23 months.

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